Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q822K5 (PKND_CHLCV) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 75. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Serine/threonine-protein kinase PknD

EC=2.7.11.1
Gene names
Name:pknD
Ordered Locus Names:CCA_00677
OrganismChlamydophila caviae (strain GPIC) [Complete proteome] [HAMAP]
Taxonomic identifier227941 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length930 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth By similarity. HAMAP-Rule MF_01957

Catalytic activity

ATP + a protein = ADP + a phosphoprotein. HAMAP-Rule MF_01957

Post-translational modification

Autophosphorylated on serine and threonine residues By similarity. HAMAP-Rule MF_01957

Sequence similarities

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.

Contains 1 protein kinase domain.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 930930Serine/threonine-protein kinase PknD HAMAP-Rule MF_01957
PRO_0000171190

Regions

Domain4 – 291288Protein kinase
Nucleotide binding10 – 189ATP By similarity

Sites

Active site1381Proton acceptor By similarity
Binding site331ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q822K5 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 37A2451522D344C1

FASTA930106,618
        10         20         30         40         50         60 
MQRYDIIRMI GKGGMGEVYL AYDPVCSRKV ALKRIREDLS DNELLKKRFL REAKIAADLV 

        70         80         90        100        110        120 
HPGVVPVFTI CSDSDPVYYT MPYIEGYTLK SLLKSVWQCD SLPKDLAEQT SVATFLSIFH 

       130        140        150        160        170        180 
KICSTVEYVH SRGILHRDLK PDNILLGLFS EVVILDWGAA LSKEMEEDFL SDIDVRIPGS 

       190        200        210        220        230        240 
LFSNMTIPGK IVGTPDYMAP ERLRGTPASE STDIYALGVI LYQMLTLSFP YRKKKGQKIS 

       250        260        270        280        290        300 
LRHQISFPEE IAPHREIPPF LSQVVMRALA ADPRERYRSV SALKADIEQH LQGSPEWTPK 

       310        320        330        340        350        360 
IVLHTQDREC WKFHEPILLS KYFPMLEVSP ALWYSLAISK IESFSEVRLE YTLLRKGLEE 

       370        380        390        400        410        420 
GFGILLPPSE GVDHGDFYHG YGFWLHIKEN ILSVSLVKNG LEIQKTSRHI DGNKEKFFIA 

       430        440        450        460        470        480 
FEKQNHRLSL IIDNIVWTIH MDYLPARGGR IGVIIQDVAD VCGNIVVLES SGSLQVSCLA 

       490        500        510        520        530        540 
VPDAFLNEKL YERAITFYRR IVESFPGRKE GYEAQFRIGI ALLEKASENS DSEGFIQALE 

       550        560        570        580        590        600 
EFSTLHNSVA APLEYLGKAL VYQRLGEYNE EVKSLLLALK RYCQRPEISR VRDHVVYRLH 

       610        620        630        640        650        660 
EALYSNHRIS LVFMLLALHV APESINASEE EHFLQNLHGK IQDTLFCNLD ISPVDFRSSK 

       670        680        690        700        710        720 
MELLLSYWSG FTPFLLGLFQ RSWDLKDYRA LADIFYTAAD LGNKEFIEEY SGILRENIRT 

       730        740        750        760        770        780 
TTFSKEIVEI LPDQLLCFLS GLEALTLQES IEKVFDGIEN LDPVLILYLF DLFAKDALIH 

       790        800        810        820        830        840 
GRGEEILKAI ALVEKYISPQ QRYRYLLPYE VLSYLWMKDA NKVYDLLSSY DESSWIDDSS 

       850        860        870        880        890        900 
HAFVLYGYWL ALAEDSSLAY LHLSGCREDS VFPRALIGVF CSPLGICEEQ LSYQERRQLL 

       910        920        930 
LQKFIFFHCL GNSEERDKCR TAYDSKERSL 

« Hide

References

[1]"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. expand/collapse author list , Rank R.G., Bavoil P.M., Fraser C.M.
Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GPIC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015925 Genomic DNA. Translation: AAP05419.1.
RefSeqNP_829541.1. NC_003361.3.

3D structure databases

ProteinModelPortalQ822K5.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227941.CCA00677.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP05419; AAP05419; CCA_00677.
GeneID1218362.
KEGGcca:CCA00677.
PATRIC20270467. VBIChlCav107360_0720.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0515.
KOK08884.
OMAYQMLTLS.
OrthoDBEOG6W45P7.
ProtClustDBPRK13184.

Enzyme and pathway databases

BioCycCCAV227941:GH8L-703-MONOMER.

Family and domain databases

Gene3D1.25.40.10. 1 hit.
HAMAPMF_01957. PknD_kinase.
InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
IPR011990. TPR-like_helical.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePKND_CHLCV
AccessionPrimary (citable) accession number: Q822K5
Entry history
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: June 1, 2003
Last modified: February 19, 2014
This is version 75 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families