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Q822K5

- PKND_CHLCV

UniProt

Q822K5 - PKND_CHLCV

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Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Chlamydophila caviae (strain GPIC)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

Catalytic activityi

ATP + a protein = ADP + a phosphoprotein.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei33 – 331ATPUniRule annotation
Active sitei138 – 1381Proton acceptorUniRule annotation

Regions

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Nucleotide bindingi10 – 189ATPUniRule annotation

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. protein serine/threonine kinase activity Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinase, Transferase

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciCCAV227941:GH8L-703-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
Gene namesi
Name:pknDUniRule annotation
Ordered Locus Names:CCA_00677
OrganismiChlamydophila caviae (strain GPIC)
Taxonomic identifieri227941 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila
ProteomesiUP000002193: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 930930Serine/threonine-protein kinase PknDPRO_0000171190Add
BLAST

Post-translational modificationi

Autophosphorylated on serine and threonine residues.UniRule annotation

Keywords - PTMi

Phosphoprotein

Interactioni

Protein-protein interaction databases

STRINGi227941.CCA00677.

Structurei

3D structure databases

ProteinModelPortaliQ822K5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini4 – 291288Protein kinaseUniRule annotationAdd
BLAST

Sequence similaritiesi

Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation
Contains 1 protein kinase domain.UniRule annotation

Phylogenomic databases

eggNOGiCOG0515.
KOiK08884.
OMAiYQMLTLS.
OrthoDBiEOG6W45P7.

Family and domain databases

Gene3Di1.25.40.10. 1 hit.
HAMAPiMF_01957. PknD_kinase.
InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
IPR011990. TPR-like_helical_dom.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q822K5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MQRYDIIRMI GKGGMGEVYL AYDPVCSRKV ALKRIREDLS DNELLKKRFL
60 70 80 90 100
REAKIAADLV HPGVVPVFTI CSDSDPVYYT MPYIEGYTLK SLLKSVWQCD
110 120 130 140 150
SLPKDLAEQT SVATFLSIFH KICSTVEYVH SRGILHRDLK PDNILLGLFS
160 170 180 190 200
EVVILDWGAA LSKEMEEDFL SDIDVRIPGS LFSNMTIPGK IVGTPDYMAP
210 220 230 240 250
ERLRGTPASE STDIYALGVI LYQMLTLSFP YRKKKGQKIS LRHQISFPEE
260 270 280 290 300
IAPHREIPPF LSQVVMRALA ADPRERYRSV SALKADIEQH LQGSPEWTPK
310 320 330 340 350
IVLHTQDREC WKFHEPILLS KYFPMLEVSP ALWYSLAISK IESFSEVRLE
360 370 380 390 400
YTLLRKGLEE GFGILLPPSE GVDHGDFYHG YGFWLHIKEN ILSVSLVKNG
410 420 430 440 450
LEIQKTSRHI DGNKEKFFIA FEKQNHRLSL IIDNIVWTIH MDYLPARGGR
460 470 480 490 500
IGVIIQDVAD VCGNIVVLES SGSLQVSCLA VPDAFLNEKL YERAITFYRR
510 520 530 540 550
IVESFPGRKE GYEAQFRIGI ALLEKASENS DSEGFIQALE EFSTLHNSVA
560 570 580 590 600
APLEYLGKAL VYQRLGEYNE EVKSLLLALK RYCQRPEISR VRDHVVYRLH
610 620 630 640 650
EALYSNHRIS LVFMLLALHV APESINASEE EHFLQNLHGK IQDTLFCNLD
660 670 680 690 700
ISPVDFRSSK MELLLSYWSG FTPFLLGLFQ RSWDLKDYRA LADIFYTAAD
710 720 730 740 750
LGNKEFIEEY SGILRENIRT TTFSKEIVEI LPDQLLCFLS GLEALTLQES
760 770 780 790 800
IEKVFDGIEN LDPVLILYLF DLFAKDALIH GRGEEILKAI ALVEKYISPQ
810 820 830 840 850
QRYRYLLPYE VLSYLWMKDA NKVYDLLSSY DESSWIDDSS HAFVLYGYWL
860 870 880 890 900
ALAEDSSLAY LHLSGCREDS VFPRALIGVF CSPLGICEEQ LSYQERRQLL
910 920 930
LQKFIFFHCL GNSEERDKCR TAYDSKERSL
Length:930
Mass (Da):106,618
Last modified:June 1, 2003 - v1
Checksum:i37A2451522D344C1
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015925 Genomic DNA. Translation: AAP05419.1.
RefSeqiNP_829541.1. NC_003361.3.

Genome annotation databases

EnsemblBacteriaiAAP05419; AAP05419; CCA_00677.
GeneIDi1218362.
KEGGicca:CCA00677.
PATRICi20270467. VBIChlCav107360_0720.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015925 Genomic DNA. Translation: AAP05419.1 .
RefSeqi NP_829541.1. NC_003361.3.

3D structure databases

ProteinModelPortali Q822K5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 227941.CCA00677.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP05419 ; AAP05419 ; CCA_00677 .
GeneIDi 1218362.
KEGGi cca:CCA00677.
PATRICi 20270467. VBIChlCav107360_0720.

Phylogenomic databases

eggNOGi COG0515.
KOi K08884.
OMAi YQMLTLS.
OrthoDBi EOG6W45P7.

Enzyme and pathway databases

BioCyci CCAV227941:GH8L-703-MONOMER.

Family and domain databases

Gene3Di 1.25.40.10. 1 hit.
HAMAPi MF_01957. PknD_kinase.
InterProi IPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
IPR023507. Ser/Thr_kinase_PknD.
IPR011990. TPR-like_helical_dom.
[Graphical view ]
Pfami PF00069. Pkinase. 1 hit.
[Graphical view ]
SUPFAMi SSF56112. SSF56112. 1 hit.
PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
    Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G.
    , Rank R.G., Bavoil P.M., Fraser C.M.
    Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GPIC.

Entry informationi

Entry nameiPKND_CHLCV
AccessioniPrimary (citable) accession number: Q822K5
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 9, 2004
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 78 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3