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Q822K5

- PKND_CHLCV

UniProt

Q822K5 - PKND_CHLCV

Protein

Serine/threonine-protein kinase PknD

Gene

pknD

Organism
Chlamydophila caviae (strain GPIC)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 77 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Together with the serine/threonine kinase Pkn1, may play a role in the specific interactions with host proteins during intracellular growth.UniRule annotation

    Catalytic activityi

    ATP + a protein = ADP + a phosphoprotein.UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei33 – 331ATPUniRule annotation
    Active sitei138 – 1381Proton acceptorUniRule annotation

    Regions

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Nucleotide bindingi10 – 189ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. protein serine/threonine kinase activity Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Kinase, Serine/threonine-protein kinase, Transferase

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciCCAV227941:GH8L-703-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Serine/threonine-protein kinase PknDUniRule annotation (EC:2.7.11.1UniRule annotation)
    Gene namesi
    Name:pknDUniRule annotation
    Ordered Locus Names:CCA_00677
    OrganismiChlamydophila caviae (strain GPIC)
    Taxonomic identifieri227941 [NCBI]
    Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila
    ProteomesiUP000002193: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 930930Serine/threonine-protein kinase PknDPRO_0000171190Add
    BLAST

    Post-translational modificationi

    Autophosphorylated on serine and threonine residues.UniRule annotation

    Keywords - PTMi

    Phosphoprotein

    Interactioni

    Protein-protein interaction databases

    STRINGi227941.CCA00677.

    Structurei

    3D structure databases

    ProteinModelPortaliQ822K5.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Domains and Repeats

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Domaini4 – 291288Protein kinaseUniRule annotationAdd
    BLAST

    Sequence similaritiesi

    Belongs to the protein kinase superfamily. Ser/Thr protein kinase family.UniRule annotation
    Contains 1 protein kinase domain.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0515.
    KOiK08884.
    OMAiYQMLTLS.
    OrthoDBiEOG6W45P7.

    Family and domain databases

    Gene3Di1.25.40.10. 1 hit.
    HAMAPiMF_01957. PknD_kinase.
    InterProiIPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR023507. Ser/Thr_kinase_PknD.
    IPR011990. TPR-like_helical.
    [Graphical view]
    PfamiPF00069. Pkinase. 1 hit.
    [Graphical view]
    SUPFAMiSSF56112. SSF56112. 1 hit.
    PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q822K5-1 [UniParc]FASTAAdd to Basket

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    MQRYDIIRMI GKGGMGEVYL AYDPVCSRKV ALKRIREDLS DNELLKKRFL    50
    REAKIAADLV HPGVVPVFTI CSDSDPVYYT MPYIEGYTLK SLLKSVWQCD 100
    SLPKDLAEQT SVATFLSIFH KICSTVEYVH SRGILHRDLK PDNILLGLFS 150
    EVVILDWGAA LSKEMEEDFL SDIDVRIPGS LFSNMTIPGK IVGTPDYMAP 200
    ERLRGTPASE STDIYALGVI LYQMLTLSFP YRKKKGQKIS LRHQISFPEE 250
    IAPHREIPPF LSQVVMRALA ADPRERYRSV SALKADIEQH LQGSPEWTPK 300
    IVLHTQDREC WKFHEPILLS KYFPMLEVSP ALWYSLAISK IESFSEVRLE 350
    YTLLRKGLEE GFGILLPPSE GVDHGDFYHG YGFWLHIKEN ILSVSLVKNG 400
    LEIQKTSRHI DGNKEKFFIA FEKQNHRLSL IIDNIVWTIH MDYLPARGGR 450
    IGVIIQDVAD VCGNIVVLES SGSLQVSCLA VPDAFLNEKL YERAITFYRR 500
    IVESFPGRKE GYEAQFRIGI ALLEKASENS DSEGFIQALE EFSTLHNSVA 550
    APLEYLGKAL VYQRLGEYNE EVKSLLLALK RYCQRPEISR VRDHVVYRLH 600
    EALYSNHRIS LVFMLLALHV APESINASEE EHFLQNLHGK IQDTLFCNLD 650
    ISPVDFRSSK MELLLSYWSG FTPFLLGLFQ RSWDLKDYRA LADIFYTAAD 700
    LGNKEFIEEY SGILRENIRT TTFSKEIVEI LPDQLLCFLS GLEALTLQES 750
    IEKVFDGIEN LDPVLILYLF DLFAKDALIH GRGEEILKAI ALVEKYISPQ 800
    QRYRYLLPYE VLSYLWMKDA NKVYDLLSSY DESSWIDDSS HAFVLYGYWL 850
    ALAEDSSLAY LHLSGCREDS VFPRALIGVF CSPLGICEEQ LSYQERRQLL 900
    LQKFIFFHCL GNSEERDKCR TAYDSKERSL 930
    Length:930
    Mass (Da):106,618
    Last modified:June 1, 2003 - v1
    Checksum:i37A2451522D344C1
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015925 Genomic DNA. Translation: AAP05419.1.
    RefSeqiNP_829541.1. NC_003361.3.

    Genome annotation databases

    EnsemblBacteriaiAAP05419; AAP05419; CCA_00677.
    GeneIDi1218362.
    KEGGicca:CCA00677.
    PATRICi20270467. VBIChlCav107360_0720.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE015925 Genomic DNA. Translation: AAP05419.1 .
    RefSeqi NP_829541.1. NC_003361.3.

    3D structure databases

    ProteinModelPortali Q822K5.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 227941.CCA00677.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP05419 ; AAP05419 ; CCA_00677 .
    GeneIDi 1218362.
    KEGGi cca:CCA00677.
    PATRICi 20270467. VBIChlCav107360_0720.

    Phylogenomic databases

    eggNOGi COG0515.
    KOi K08884.
    OMAi YQMLTLS.
    OrthoDBi EOG6W45P7.

    Enzyme and pathway databases

    BioCyci CCAV227941:GH8L-703-MONOMER.

    Family and domain databases

    Gene3Di 1.25.40.10. 1 hit.
    HAMAPi MF_01957. PknD_kinase.
    InterProi IPR011009. Kinase-like_dom.
    IPR000719. Prot_kinase_dom.
    IPR017441. Protein_kinase_ATP_BS.
    IPR008271. Ser/Thr_kinase_AS.
    IPR023507. Ser/Thr_kinase_PknD.
    IPR011990. TPR-like_helical.
    [Graphical view ]
    Pfami PF00069. Pkinase. 1 hit.
    [Graphical view ]
    SUPFAMi SSF56112. SSF56112. 1 hit.
    PROSITEi PS00107. PROTEIN_KINASE_ATP. 1 hit.
    PS50011. PROTEIN_KINASE_DOM. 1 hit.
    PS00108. PROTEIN_KINASE_ST. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
      Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G.
      , Rank R.G., Bavoil P.M., Fraser C.M.
      Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: GPIC.

    Entry informationi

    Entry nameiPKND_CHLCV
    AccessioniPrimary (citable) accession number: Q822K5
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: November 9, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 77 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3