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Q822E7 (G6PI_CHLCV) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 67. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:CCA_00736
OrganismChlamydophila caviae (strain GPIC) [Complete proteome] [HAMAP]
Taxonomic identifier227941 [NCBI]
Taxonomic lineageBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila

Protein attributes

Sequence length527 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolytic process

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 527527Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180622

Sites

Active site3471Proton donor By similarity
Active site3781 By similarity
Active site4931 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q822E7 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 405C5DE6F5083469

FASTA52757,881
        10         20         30         40         50         60 
MNKKGFLDSS STKILQDLAV APIDLTAPGV ISKERIERFS LSVEGFTLSY ATERVDEGIL 

        70         80         90        100        110        120 
SALEDLASER GLIESMQAMQ NGEVVNYIEN FPSESRPALH TATRAWVKES PLQGNAEDIS 

       130        140        150        160        170        180 
LRSKIEAQRL KDFLNRYRDV FTTIVQIGIG GSELGPKALH WALKGCCPSD KKVYFVSNVD 

       190        200        210        220        230        240 
PDNAAEVLQE IDCAKTLVVT VSKSGTTLET AVNEELLADH FLKQGLHFQD HFIAVTCEGS 

       250        260        270        280        290        300 
PMDDTSKYLE VFHIWDSIGG RYSSTSMVGG VVLGFAYGFD VFLQLLEGAA SMDLAALEPR 

       310        320        330        340        350        360 
MSENLPLLSA MLGIWNRNFL RYPTSAVVPY ATGLEYFPAH LQQCGMESNG KSVAQTGEVI 

       370        380        390        400        410        420 
GFATSPILWG EVGTNSQHSF FQCLHQGSDI VPIEFIGFQE NQRGKDIVIA GSSSSQKLFA 

       430        440        450        460        470        480 
NMVAQSIALA KGRENTNPNK NFRGNRPSSL LVSERLTPYT MGALLAFYEH KIVFQGFCWG 

       490        500        510        520 
INSFDQEGVT LGKDLANQVL QVMQGQEKEG ALLEAEALLR LFNNIKK 

« Hide

References

[1]"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. expand/collapse author list , Rank R.G., Bavoil P.M., Fraser C.M.
Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: GPIC.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE015925 Genomic DNA. Translation: AAP05477.1.
RefSeqNP_829599.1. NC_003361.3.

3D structure databases

ProteinModelPortalQ822E7.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING227941.CCA00736.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP05477; AAP05477; CCA_00736.
GeneID1218421.
KEGGcca:CCA00736.
PATRIC20270597. VBIChlCav107360_0782.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
KOK01810.
OMAMIALTHY.
OrthoDBEOG64R61J.

Enzyme and pathway databases

BioCycCCAV227941:GH8L-765-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_CHLCV
AccessionPrimary (citable) accession number: Q822E7
Entry history
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: June 1, 2003
Last modified: June 11, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways