SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q821Z7

- GLMS_CHLCV

UniProt

Q821Z7 - GLMS_CHLCV

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
glmS, CCA_00788
Organism
Chlamydophila caviae (strain GPIC)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei604 – 6041For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciCCAV227941:GH8L-820-MONOMER.

Protein family/group databases

MEROPSiC44.971.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Ordered Locus Names:CCA_00788
OrganismiChlamydophila caviae (strain GPIC)
Taxonomic identifieri227941 [NCBI]
Taxonomic lineageiBacteriaChlamydiaeChlamydialesChlamydiaceaeChlamydia/Chlamydophila groupChlamydophila
ProteomesiUP000002193: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 609608Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation
PRO_0000135317Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi227941.CCA00788.

Structurei

3D structure databases

ProteinModelPortaliQ821Z7.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 219218Glutamine amidotransferase type-2
Add
BLAST
Domaini280 – 426147SIS 1
Add
BLAST
Domaini458 – 599142SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
KOiK00820.
OMAiFYTHAGP.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q821Z7-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIFGYIGA KLAVPVVLDG LAKLEYRGYD SAGLAAVIPE RLFVRKTVGR    50
VDELRSSLEK ENVPSSLAIG HTRWATHGVP TVKNAHPHVD ENSACAIVHN 100
GIIDNFKELR SLLISEGISF SSDTDSEVIA QLFAFRYQAT GDLVHSFSWT 150
LSQLQGSFSC GLIHKDHPNV LLCAAQESPL IIGLGEKESF IASDARAFLK 200
HTKSIQALAS GELAVVGLGS EVETYNFALK RIHKEVRQVV YTDADSDKQG 250
YSYYMLKEIY EQPEVLERLI HKYLDQQGCI SEKFLNGFSI EDFDEISIVA 300
CGSSYHAGFL AKYIIESLVS IPVHVEVASE FRYRQAYIGK KTLAILISQS 350
GETADTLAAL KEFRRRQVAC VLGICNVEES ALATGVDHCL FLEAGIEIGV 400
ASTKAFTAQL LLLILLGLKL ATLKQTLSLE EHRACGKGLF ELPELCNRLL 450
ANENLHSWAN DYCDEDRFIF LGRRLMYPIC MEAALKLKEI AYVEANCYPA 500
GEMKHGPIAL ISQGSPVITF CGDPVVYEKM VGCIMEVKAR QAHVIAVASE 550
SQEDIAAVSD AQIYVPNSHP LVSPILYTIV GQIMAYTMAL KKGYEIDRPR 600
NLAKSVTVE 609
Length:609
Mass (Da):67,025
Last modified:January 23, 2007 - v3
Checksum:i875C07615FF49A88
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015925 Genomic DNA. Translation: AAP05529.1.
RefSeqiNP_829651.1. NC_003361.3.

Genome annotation databases

EnsemblBacteriaiAAP05529; AAP05529; CCA_00788.
GeneIDi1218473.
KEGGicca:CCA00788.
PATRICi20270709. VBIChlCav107360_0835.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE015925 Genomic DNA. Translation: AAP05529.1 .
RefSeqi NP_829651.1. NC_003361.3.

3D structure databases

ProteinModelPortali Q821Z7.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 227941.CCA00788.

Protein family/group databases

MEROPSi C44.971.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP05529 ; AAP05529 ; CCA_00788 .
GeneIDi 1218473.
KEGGi cca:CCA00788.
PATRICi 20270709. VBIChlCav107360_0835.

Phylogenomic databases

eggNOGi COG0449.
KOi K00820.
OMAi FYTHAGP.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci CCAV227941:GH8L-820-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae."
    Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G.
    , Rank R.G., Bavoil P.M., Fraser C.M.
    Nucleic Acids Res. 31:2134-2147(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: GPIC.

Entry informationi

Entry nameiGLMS_CHLCV
AccessioniPrimary (citable) accession number: Q821Z7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: July 25, 2003
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 74 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi