Q821Z6 (GLMM_CHLCV) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Phosphoglucosamine mutase
EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	CCA_00789

Organism

Chlamydophila caviae [Complete proteome] [HAMAP]

Taxonomic identifier

83557 [NCBI]

Taxonomic lineage

Bacteria › Chlamydiae › Chlamydiales › Chlamydiaceae › Chlamydia/Chlamydophila group › Chlamydophila

Protein attributes

Sequence length	458 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity. HAMAP MF_01554_B
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554_B
Cofactor	Binds 1 magnesium ion per subunit By similarity. HAMAP MF_01554_B
Post-translational modification	Activated by phosphorylation By similarity. HAMAP MF_01554_B
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: InterPro phosphoglucosamine mutase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 458	458	Phosphoglucosamine mutase HAMAP MF_01554_B		PRO_0000147871
Sites
	Active site	106	1	Phosphoserine intermediate By similarity
	Metal binding	106	1	Magnesium; via phosphate group By similarity
	Metal binding	247	1	Magnesium By similarity
	Metal binding	249	1	Magnesium By similarity
	Metal binding	251	1	Magnesium By similarity
Amino acid modifications
	Modified residue	106	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q821Z6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 23DC95E6F93FFDA0	FASTA	458	49,670
	10 20 30 40 50 60 MTREEKQLFG TDGIRGRANY EPMTVELSVL LGKAVAGVLQ ERKPGKHRVV VGKDTRLSGY 70 80 90 100 110 120 MFENALVAGL TSMGIETLVL GPIPTPGVAF ITRAYRADAG IMISASHNPY WDNGIKIFSS 130 140 150 160 170 180 EGFKISDVIE RRIEQMVACR DFGNFPEDYA VGKNKRVVDA MGRYIEFAKA TFPKGRTLKG 190 200 210 220 230 240 LKIVLDCAHG AAYKVAPSVF EELDAEVICY GCEPTGSNIN DNCGALFPSV IQKAVIEHKA 250 260 270 280 290 300 DVGIALDGDG DRIIMVNEKG HIVDGDMILS ICASDLKKKA LLNGNRVVAT VMTNFGVLKY 310 320 330 340 350 360 LESLGIETLI SSVGDRHVLQ NMLEHEANLG GEQSGHMIFL DYNTTGDGIV SALQVLRIMI 370 380 390 400 410 420 ESESTLSDLT SLIVKSPQAL INVSVKEKIP LDTLPIVQEA LRDVRSSLGD SGRVLLRYSG 430 440 450 TENICRVMVE GLKKHQVDSL AKTIADIVDS ELGAGIIE

References

[1]

"Genome sequence of Chlamydophila caviae (Chlamydia psittaci GPIC): examining the role of niche-specific genes in the evolution of the Chlamydiaceae." Read T.D., Myers G.S.A., Brunham R.C., Nelson W.C., Paulsen I.T., Heidelberg J.F., Holtzapple E.K., Khouri H.M., Federova N.B., Carty H.A., Umayam L.A., Haft D.H., Peterson J.D., Beanan M.J., White O., Salzberg S.L., Hsia R.-C., McClarty G. , Rank R.G., Bavoil P.M., Fraser C.M. Nucleic Acids Res. 31:2134-2147(2003) [PubMed: 12682364] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: GPIC.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE015925 Genomic DNA. Translation: AAP05530.1.
RefSeq	NP_829652.1. NC_003361.3.
3D structure databases
ProteinModelPortal	Q821Z6.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	1218474.
GenomeReviews	Gene locus CCA_00789 in contig AE015925_GR.
KEGG	cca:CCA00789.
PATRIC	20270711. VBIChlCav107360_0836.
TIGR	CCA_00789.
Phylogenomic databases
HOGENOM	HBG644964.
OMA	IGSAKRI.
PhylomeDB	Q821Z6.
ProtClustDB	PRK14314.
Enzyme and pathway databases
BioCyc	CCAV227941:CCA_00789-MONOMER.
Family and domain databases
HAMAP	MF_01554_B. GlmM_B. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. Alpha-D-phosphohexomutase_SF. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
KO	K03431.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
SUPFAM	SSF53738. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
TIGRFAMs	TIGR01455. GlmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_CHLCV

Accession

Primary (citable) accession number: Q821Z6

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	June 1, 2003
Last modified:	January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program