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Protein
Submitted name:

Putative serine/threonine protein kinase

Gene

pkn18

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-5066-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative serine/threonine protein kinaseImported
Gene namesi
Name:pkn18Imported
Ordered Locus Names:SAV_5005Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000000428: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_5005.

Structurei

3D structure databases

ProteinModelPortaliQ81ZX1.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037187.
OMAiWRAEDET.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81ZX1-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSEAERAGAS RQDKSGRLLA GRYRLGDVLG RGGMGTVWRA EDETLGRTVA
60 70 80 90 100
VKELRFPTSI DEDEKRRLIT RTLREAKAIA RIRNNSAVTV FDVVDEDNRP
110 120 130 140 150
WIVMELVEGK SLAEAIREDG LLEPKRAAEV GLAILDVLRA AHREGILHRD
160 170 180 190 200
VKPSNVLIAE DGRVVLTDFG IAQVEGDPSI TSTGMLVGAP SYISPERARG
210 220 230 240 250
HKPGPAADLW SLGGLLYASV EGVPPYDKGS AIATLTAVMT EPLEEPKNAG
260 270 280 290 300
PLRSVIYGLL AKDPEQRLDD AGARAMLNEV LHAPQPKEPE PVDATRVVAL
310 320 330 340 350
PPVPEEGTGK GSSGGSGAKR GEEAADRFRG ALRSVRKAAG AATASAAARA
360 370 380 390 400
KSGGTDVSGG TGAAGAGTSS AGSSASASAP APGKPGAAAV GKPNPSSAGK
410 420 430 440 450
PGSSAAATPA GTGSGVGQGT AVGGGGRESA VVGSNSGPVK PSSGWPVVPE
460 470 480 490 500
PDRPPRSVPR APLTDVVPRR TLVIVAVVVV LAVLGVVLAL TLGGDDGSSK
510 520 530 540 550
DNKGSSDTKA AASSGTSSGT TAGSSGTPKA GGSGSGSGGT HTDSGSKDNT
560 570 580 590 600
GTGSDEQETD DSSSAGTASG SGGSDDSGSG SGDSSVKTYK SSQGFSIGLP
610 620 630 640 650
KGWKYQSTGA AGARFTGPDG QKLLVGWTTT PKDDPVADWK NQEQYMVRSQ
660 670 680 690 700
YKRIRIEQVD YRGWNTADWE FTYTEGGTKY RSIDRGFVVN AHQGYALMYT
710 720
AKASEWDSDL RKDTWQTLAK TFQPKS
Length:726
Mass (Da):74,603
Last modified:June 1, 2003 - v1
Checksum:i595CF0A9680E541F
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72717.1.
RefSeqiNP_826182.1. NC_003155.4.
WP_010986410.1. NC_003155.4.

Genome annotation databases

EnsemblBacteriaiBAC72717; BAC72717; SAV_5005.
GeneIDi1211176.
KEGGisma:SAV_5005.
PATRICi23723924. VBIStrAve112782_5333.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72717.1.
RefSeqiNP_826182.1. NC_003155.4.
WP_010986410.1. NC_003155.4.

3D structure databases

ProteinModelPortaliQ81ZX1.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_5005.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC72717; BAC72717; SAV_5005.
GeneIDi1211176.
KEGGisma:SAV_5005.
PATRICi23723924. VBIStrAve112782_5333.

Phylogenomic databases

HOGENOMiHOG000037187.
OMAiWRAEDET.
OrthoDBiEOG6B35XT.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-5066-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
    Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
    Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680Imported.
  2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
    Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
    Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiQ81ZX1_STRAW
AccessioniPrimary (citable) accession number: Q81ZX1
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 4, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.