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Protein
Submitted name:

Putative serine/threonine protein kinase

Gene

pkn22

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseUniRule annotationImported, Transferase

Keywords - Ligandi

ATP-bindingUniRule annotation, Nucleotide-binding

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-5071-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative serine/threonine protein kinaseImported
Gene namesi
Name:pkn22Imported
Ordered Locus Names:SAV_5010Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaStreptomycetalesStreptomycetaceaeStreptomyces
ProteomesiUP000000428 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_5010.

Structurei

3D structure databases

ProteinModelPortaliQ81ZW7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000037187.
OMAiEPRVPDH.
OrthoDBiEOG600DXM.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81ZW7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNNGGVSYG ADEPTSFGLQ PPRPGVPHPG NPYAQPQPQP QPQPQPQPQP
60 70 80 90 100
QPQPQPQPQP QSHAHAHAHP TQQMPPQAMP ETPPGEPGTG RLIAGRYRLL
110 120 130 140 150
AKLGHGGMGT VWRAKDETVD REVAVKEPRV PDHLPERERA NVFERMRREA
160 170 180 190 200
RAAARLDHPA VVNVHDVAVV DGRPWIVMEL VQGRSLGAAL QEGTLGARET
210 220 230 240 250
AKIGLEVLGA LEAAHAAGIL HRDVKPDNVL LGRHDRVVLT DFGIAQIEGE
260 270 280 290 300
TNLTDTGGFV GSPEYIAPER VLGQRPGPAS DLWSLGVVLY AAAEGVSPFR
310 320 330 340 350
RSNTPATLQS VLNATPAAPA AAKGTLAQVI NGLLNKDPAR RPNAAEVRRL
360 370 380 390 400
LEDAARPPQQ TQVVQIAGPG GKGFRVGRKA LFGLGAAVVA AAVAAYLVIA
410 420 430 440 450
DPFAGPLPDT WKQREVPRLD ATLAVPADYQ VSRPEKSDTD KNWVTYSDWS
460 470 480 490 500
GSIWIGLHLA KKSEDTSNQI KDSAAAEMYA ENGEFKESGA YELSMPEKPK
510 520 530 540 550
TRTAETSYQG KKAAENTVVY TTTDSQNPRP REVRIFYYKN SAGNMYKLTV
560 570
SYPGKGDFTE RGREVAKTAI ANLDVDKL
Length:578
Mass (Da):62,333
Last modified:June 1, 2003 - v1
Checksum:i1C35E8C3B3B3A691
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72722.1.

Genome annotation databases

EnsemblBacteriaiBAC72722; BAC72722; SAV_5010.
KEGGisma:SAV_5010.
PATRICi23723934. VBIStrAve112782_5338.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72722.1.

3D structure databases

ProteinModelPortaliQ81ZW7.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_5010.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC72722; BAC72722; SAV_5010.
KEGGisma:SAV_5010.
PATRICi23723934. VBIStrAve112782_5338.

Phylogenomic databases

HOGENOMiHOG000037187.
OMAiEPRVPDH.
OrthoDBiEOG600DXM.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-5071-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 1 hit.
PROSITEiPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
    Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
    Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680Imported.
  2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
    Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
    Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiQ81ZW7_STRAW
AccessioniPrimary (citable) accession number: Q81ZW7
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 22, 2015
This is version 95 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.