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Protein
Submitted name:

Putative serine/threonine protein kinase

Gene

pkn23

Organism
Streptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. ATP binding Source: InterPro
  2. protein serine/threonine kinase activity Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Kinase, Serine/threonine-protein kinaseImported, Transferase

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-5164-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Putative serine/threonine protein kinaseImported
Gene namesi
Name:pkn23Imported
Ordered Locus Names:SAV_5100Imported
OrganismiStreptomyces avermitilis (strain ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680)Imported
Taxonomic identifieri227882 [NCBI]
Taxonomic lineageiBacteriaActinobacteriaActinobacteridaeActinomycetalesStreptomycineaeStreptomycetaceaeStreptomyces
ProteomesiUP000000428 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi227882.SAV_5100.

Structurei

3D structure databases

ProteinModelPortaliQ81ZW6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000115552.
KOiK08884.
OMAiMHPMLTD.
OrthoDBiEOG6B35XT.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81ZW6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRPVGSKYLL EEPLGRGATG TVWRARQRET AGAEAAVAGQ PGETVAIKVL
60 70 80 90 100
KEELASDADV VMRFLRERSV LLRLTHPNIV RVRDLVVEGD LLALVMDLVD
110 120 130 140 150
GPDLHRYLRE NGPFTPVAAA LLTAQVADAL AASHADGVVH RDLKPANVLL
160 170 180 190 200
KQDGGQMHPM LTDFGIARLA DSPGLTRTHE FVGTPAYVAP ESAEGRPQTS
210 220 230 240 250
AVDIYGAGIL LYELITGRPP FAGGSALEVL HQHLSAEPRR PSTVPDPLWT
260 270 280 290 300
VIERCLSKNP DRRPSAENLA RALRVVAGGV GVHASAAQIA AAEGVGALLA
310 320 330 340 350
PDPTPATVPG VPGAADPTQV LPQGAGAYDP NAATSFLPHT SGDADPTSVL
360 370 380 390 400
PHRGAADPTA VMPPVPQHQP GGPNGQSGPE EPHPWQNQLR AARDRNEQTQ
410 420 430 440 450
VQSYLDPSED PLRRRPQRQV ARPQQQPQQQ PGPGYGYPQQ QPQQYAPQGQ
460 470 480 490 500
PQRQPRRQPQ PQQYAPAPQQ QPQRQPQRHQ PQPRQPAPRP EPEPRQPRQR
510 520 530 540 550
GANPMKIPGL GCLKGCLFTV IILFVAGWLV WELSPLQEWI GTGRGYWSEL
560 570
SHWFNKVSGW IGDLGGGSDK TSN
Length:573
Mass (Da):61,880
Last modified:June 1, 2003 - v1
Checksum:i9588CBA81436A32E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72812.1.
RefSeqiNP_826277.1. NC_003155.4.
WP_010986505.1. NC_003155.4.

Genome annotation databases

EnsemblBacteriaiBAC72812; BAC72812; SAV_5100.
KEGGisma:SAV_5100.
PATRICi23724128. VBIStrAve112782_5432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BA000030 Genomic DNA. Translation: BAC72812.1.
RefSeqiNP_826277.1. NC_003155.4.
WP_010986505.1. NC_003155.4.

3D structure databases

ProteinModelPortaliQ81ZW6.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi227882.SAV_5100.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiBAC72812; BAC72812; SAV_5100.
KEGGisma:SAV_5100.
PATRICi23724128. VBIStrAve112782_5432.

Phylogenomic databases

HOGENOMiHOG000115552.
KOiK08884.
OMAiMHPMLTD.
OrthoDBiEOG6B35XT.

Enzyme and pathway databases

BioCyciSAVE227882:GJU1-5164-MONOMER.

Family and domain databases

InterProiIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR002290. Ser/Thr_dual-sp_kinase.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamiPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTiSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMiSSF56112. SSF56112. 2 hits.
PROSITEiPS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
    Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
    Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2000) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680Imported.
  2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
    Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
    Nat. Biotechnol. 21:526-531(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Entry informationi

Entry nameiQ81ZW6_STRAW
AccessioniPrimary (citable) accession number: Q81ZW6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 1, 2015
This is version 82 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.