<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

1. ATP binding Source: UniProtKB-KW
2. protein serine/threonine kinase activity Source: UniProtKB-KW

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Molecular functionⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Ligandⁱ

Enzyme and pathway databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>Provides information on the tertiary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

<p>Provides information about the sequence similarity with other proteins.</p><p><a href='../manual/sequence_similarities' target='_top'>More...</a></p>Sequence similaritiesⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the canonical sequence displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MPGNSGGGVP GLLVTGRYRL VESIGQGGMG RVWRATDEML DRQVAVKEMR 
        60         70         80         90        100
IDGLDAEDTR TRRERTLREA RATARISHPN VVRVYDVVDE SDRLWIVMEL 
       110        120        130        140        150
VDGRSLERIV VEDGPLGPGE TARIGRELVA ALRQVHAGGV LHRDIKPGNV 
       160        170        180        190        200
LVENLGHRVV LTDFGIAAIQ DAKALTMVGM LVGSPDYMAP ERVSGRPQGP 
       210        220        230        240        250
PSDVWSLGAT LCAALGGHSP FSRSTTLATL HAVLYEEPEL PTEAGGLRQI 
       260        270        280        290        300
LAALLEKEPS VRPGLEEVAA ALEALVATGT SVAGAGDAGA GAAGAGVEAA 
       310        320        330        340        350
GVEVAGSGSG DGGNGGDRGE GAVGERGAGL GAGSGGEPGA GSGPELRVGP 
       360        370        380        390        400
GAESGAGAGA ESEVGAVPRG VRQPGEEGEP EQGGPDAGSG GRRLESPTRA 
       410        420        430        440        450
LLDTALIRAA RTAPEETRPD ADPRWSEPVQ DAIPGRPTRA VPPEAPPTRE 
       460        470        480        490        500
TPAVGPGHTA VTQPSHSPAP APALPTPLPF PAQPHHPEAP LVPPTASPTA 
       510        520        530        540        550
SPTASPTASP AVGNASTEAP SAGRAEPLAS GVPERAGAGE RPSRGGAAPG 
       560        570        580        590        600
TGSHAALANA VTASRLPGWP GAAPTSSPMS PGELPGPALP SAPRPPRHRR 
       610        620        630        640        650
RMGLAAAGGV VAAGAVAVVV IAATGGSPGH DRDASSATSS APSASSGGPS 
       660        670        680        690        700
RSPTVDGTSR PPSLPPGSRT EAGMYAWVPP KGWKRVVQSG TEVHYTSPDA 
       710        720        730        740        750
QQEILANATP ARGDLLKQWQ VAEEDREKGL NYRRIRLERT TFRGAPAVVW 
       760        770        780        790        800
EYNVTAKGQY WHVRLLGFRS RGTSYELSTW YHPDIEGSAV PAYERVKKSF 

TPL                                             

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p> Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>Contains the literature citations that are the sources of data used to annotate the entry. Each reference is numbered and contains several subsections allowing a precise description of a given citation.</p><p><a href='../manual/publications_section' target='_top'>More...</a></p>Publicationsⁱ

1. "Genome sequence of an industrial microorganism Streptomyces avermitilis: deducing the ability of producing secondary metabolites."
   Omura S., Ikeda H., Ishikawa J., Hanamoto A., Takahashi C., Shinose M., Takahashi Y., Horikawa H., Nakazawa H., Osonoe T., Kikuchi H., Shiba T., Sakaki Y., Hattori M.
   Proc. Natl. Acad. Sci. U.S.A. 98:12215-12220(2001) [PubMed] [Europe PMC] [Abstract]
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
   Strain: ATCC 31267 / DSM 46492 / JCM 5070 / NCIMB 12804 / NRRL 8165 / MA-4680Imported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • Proteomes:UP000000428
   .
   
2. "Complete genome sequence and comparative analysis of the industrial microorganism Streptomyces avermitilis."
   Ikeda H., Ishikawa J., Hanamoto A., Shinose M., Kikuchi H., Shiba T., Sakaki Y., Hattori M., Omura S.
   Nat. Biotechnol. 21:526-531(2003) [PubMed] [Europe PMC] [Abstract]
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

External Data

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ