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Q81ZS7

- SYQ_NITEU

UniProt

Q81ZS7 - SYQ_NITEU

Protein

Glutamine--tRNA ligase

Gene

glnS1

more
Organism
Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
Status
Reviewed - Annotation score: 3 out of 5- Protein inferred from homologyi
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    • History
      Entry version 68 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Binding sitei273 – 2731ATPUniRule annotation

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-HAMAP
    2. glutamine-tRNA ligase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glutaminyl-tRNA aminoacylation Source: InterPro
    2. glutamyl-tRNA aminoacylation Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Aminoacyl-tRNA synthetase, Ligase

    Keywords - Biological processi

    Protein biosynthesis

    Keywords - Ligandi

    ATP-binding, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciNEUR228410:GJNO-2401-MONOMER.
    NEUR228410:GJNO-2408-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
    Alternative name(s):
    Glutaminyl-tRNA synthetaseUniRule annotation
    Short name:
    GlnRSUniRule annotation
    Gene namesi
    Name:glnS1UniRule annotation
    Ordered Locus Names:NE2356
    AND
    Name:glnS2UniRule annotation
    Ordered Locus Names:NE2363
    OrganismiNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
    Taxonomic identifieri228410 [NCBI]
    Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas
    ProteomesiUP000001416: Chromosome

    Subcellular locationi

    Cytoplasm UniRule annotation

    GO - Cellular componenti

    1. cytoplasm Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Cytoplasm

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Chaini1 – 556556Glutamine--tRNA ligasePRO_0000195840Add
    BLAST

    Proteomic databases

    PRIDEiQ81ZS7.

    Interactioni

    Subunit structurei

    Monomer.UniRule annotation

    Protein-protein interaction databases

    STRINGi228410.NE2363.

    Structurei

    3D structure databases

    ProteinModelPortaliQ81ZS7.
    SMRiQ81ZS7. Positions 9-553.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi34 – 4411"HIGH" regionAdd
    BLAST
    Motifi270 – 2745"KMSKS" region

    Sequence similaritiesi

    Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG0008.
    HOGENOMiHOG000259232.
    KOiK01886.
    OMAiKSDSWID.
    OrthoDBiEOG6DRPF7.
    PhylomeDBiQ81ZS7.

    Family and domain databases

    Gene3Di1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    HAMAPiMF_00126. Gln_tRNA_synth.
    InterProiIPR004514. Gln-tRNA-synth.
    IPR022861. Gln_tRNA_ligase_bac.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view]
    PANTHERiPTHR10119. PTHR10119. 1 hit.
    PfamiPF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    [Graphical view]
    PRINTSiPR00987. TRNASYNTHGLU.
    SUPFAMiSSF50715. SSF50715. 1 hit.
    TIGRFAMsiTIGR00440. glnS. 1 hit.
    PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q81ZS7-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNTPSSPAHF IRNIIEEDNR TGKWNGRVET RFPPEPNGYL HIGHAKSICL    50
    NFGLALEYGG VCHLRFDDTN PEKEAQEYVD AIIESVRWLG FDWKEHLYYA 100
    SDYFDQLYEF AEYLITQGKA YVDSLSADEI RRLRGTLTEA GTNSPYRDRS 150
    AEENLDLFRR MRAGEFPDGV HVLRARIDMA SPNINLRDPV IYRIRHIHHQ 200
    RTGDKWCIYP MYDYTHCISD ALERITHSLC TLEFEDHRPL YDWVLDQLAE 250
    KIPCHPQQIE FARLNLTYSV MSKRKLIDLV ENKLVDGWND PRMNTLAGLR 300
    RRGYTPESIR LFAERIGISK ADSWIDMTIL EDCLREDLNE RALRRIAVLD 350
    PVSLIIDNFP DGHEETCYAP NHPQKPELGT RELRLTKQLY IDREDFMEIP 400
    NKGFFRLAPG AEVRLRYAFI IKCTHVVKDD QGKILEIHCV YDPDTKSGTA 450
    GAETRKVRGN IHWLSATYAK AVEIRLYDRL FIDSHPDTEG KDFKISLNPN 500
    SKEVITGYVE PSLCEAQPEQ RFQFERHGYF VADLADTGPG KPIFNRTVSL 550
    RNTWKK 556
    Length:556
    Mass (Da):64,605
    Last modified:June 1, 2003 - v1
    Checksum:i2AAA9D841E04BF8C
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL954747 Genomic DNA. Translation: CAD86268.1.
    AL954747 Genomic DNA. Translation: CAD86275.1.
    RefSeqiNP_842353.1. NC_004757.1.
    NP_842358.1. NC_004757.1.
    WP_011112836.1. NC_004757.1.

    Genome annotation databases

    EnsemblBacteriaiCAD86268; CAD86268; NE2356.
    CAD86275; CAD86275; NE2363.
    GeneIDi1083323.
    1083330.
    KEGGineu:NE2356.
    neu:NE2363.
    PATRICi22716122. VBINitEur56163_2638.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AL954747 Genomic DNA. Translation: CAD86268.1 .
    AL954747 Genomic DNA. Translation: CAD86275.1 .
    RefSeqi NP_842353.1. NC_004757.1.
    NP_842358.1. NC_004757.1.
    WP_011112836.1. NC_004757.1.

    3D structure databases

    ProteinModelPortali Q81ZS7.
    SMRi Q81ZS7. Positions 9-553.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 228410.NE2363.

    Proteomic databases

    PRIDEi Q81ZS7.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai CAD86268 ; CAD86268 ; NE2356 .
    CAD86275 ; CAD86275 ; NE2363 .
    GeneIDi 1083323.
    1083330.
    KEGGi neu:NE2356.
    neu:NE2363.
    PATRICi 22716122. VBINitEur56163_2638.

    Phylogenomic databases

    eggNOGi COG0008.
    HOGENOMi HOG000259232.
    KOi K01886.
    OMAi KSDSWID.
    OrthoDBi EOG6DRPF7.
    PhylomeDBi Q81ZS7.

    Enzyme and pathway databases

    BioCyci NEUR228410:GJNO-2401-MONOMER.
    NEUR228410:GJNO-2408-MONOMER.

    Family and domain databases

    Gene3Di 1.10.1160.10. 1 hit.
    2.40.240.10. 2 hits.
    3.40.50.620. 2 hits.
    HAMAPi MF_00126. Gln_tRNA_synth.
    InterProi IPR004514. Gln-tRNA-synth.
    IPR022861. Gln_tRNA_ligase_bac.
    IPR000924. Glu/Gln-tRNA-synth.
    IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
    IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
    IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
    IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
    IPR011035. Ribosomal_L25/Gln-tRNA_synth.
    IPR014729. Rossmann-like_a/b/a_fold.
    [Graphical view ]
    PANTHERi PTHR10119. PTHR10119. 1 hit.
    Pfami PF00749. tRNA-synt_1c. 1 hit.
    PF03950. tRNA-synt_1c_C. 1 hit.
    [Graphical view ]
    PRINTSi PR00987. TRNASYNTHGLU.
    SUPFAMi SSF50715. SSF50715. 1 hit.
    TIGRFAMsi TIGR00440. glnS. 1 hit.
    PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea."
      Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.
      J. Bacteriol. 185:2759-2773(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: ATCC 19718 / NBRC 14298.

    Entry informationi

    Entry nameiSYQ_NITEU
    AccessioniPrimary (citable) accession number: Q81ZS7
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: April 26, 2004
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 68 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. Aminoacyl-tRNA synthetases
      List of aminoacyl-tRNA synthetase entries
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3