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Protein

Glutamine--tRNA ligase

Gene

glnS1

more
Organism
Nitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei273 – 2731ATPUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciNEUR228410:GJNO-2401-MONOMER.
NEUR228410:GJNO-2408-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--tRNA ligaseUniRule annotation (EC:6.1.1.18UniRule annotation)
Alternative name(s):
Glutaminyl-tRNA synthetaseUniRule annotation
Short name:
GlnRSUniRule annotation
Gene namesi
Name:glnS1UniRule annotation
Ordered Locus Names:NE2356
AND
Name:glnS2UniRule annotation
Ordered Locus Names:NE2363
OrganismiNitrosomonas europaea (strain ATCC 19718 / NBRC 14298)
Taxonomic identifieri228410 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaBetaproteobacteriaNitrosomonadalesNitrosomonadaceaeNitrosomonas
ProteomesiUP000001416 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 556556Glutamine--tRNA ligasePRO_0000195840Add
BLAST

Proteomic databases

PRIDEiQ81ZS7.

Interactioni

Subunit structurei

Monomer.UniRule annotation

Protein-protein interaction databases

STRINGi228410.NE2363.

Structurei

3D structure databases

ProteinModelPortaliQ81ZS7.
SMRiQ81ZS7. Positions 9-553.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi34 – 4411"HIGH" regionAdd
BLAST
Motifi270 – 2745"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiEOG6DRPF7.
PhylomeDBiQ81ZS7.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81ZS7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTPSSPAHF IRNIIEEDNR TGKWNGRVET RFPPEPNGYL HIGHAKSICL
60 70 80 90 100
NFGLALEYGG VCHLRFDDTN PEKEAQEYVD AIIESVRWLG FDWKEHLYYA
110 120 130 140 150
SDYFDQLYEF AEYLITQGKA YVDSLSADEI RRLRGTLTEA GTNSPYRDRS
160 170 180 190 200
AEENLDLFRR MRAGEFPDGV HVLRARIDMA SPNINLRDPV IYRIRHIHHQ
210 220 230 240 250
RTGDKWCIYP MYDYTHCISD ALERITHSLC TLEFEDHRPL YDWVLDQLAE
260 270 280 290 300
KIPCHPQQIE FARLNLTYSV MSKRKLIDLV ENKLVDGWND PRMNTLAGLR
310 320 330 340 350
RRGYTPESIR LFAERIGISK ADSWIDMTIL EDCLREDLNE RALRRIAVLD
360 370 380 390 400
PVSLIIDNFP DGHEETCYAP NHPQKPELGT RELRLTKQLY IDREDFMEIP
410 420 430 440 450
NKGFFRLAPG AEVRLRYAFI IKCTHVVKDD QGKILEIHCV YDPDTKSGTA
460 470 480 490 500
GAETRKVRGN IHWLSATYAK AVEIRLYDRL FIDSHPDTEG KDFKISLNPN
510 520 530 540 550
SKEVITGYVE PSLCEAQPEQ RFQFERHGYF VADLADTGPG KPIFNRTVSL

RNTWKK
Length:556
Mass (Da):64,605
Last modified:June 1, 2003 - v1
Checksum:i2AAA9D841E04BF8C
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954747 Genomic DNA. Translation: CAD86268.1.
AL954747 Genomic DNA. Translation: CAD86275.1.
RefSeqiNP_842353.1. NC_004757.1.
NP_842358.1. NC_004757.1.
WP_011112836.1. NC_004757.1.

Genome annotation databases

EnsemblBacteriaiCAD86268; CAD86268; NE2356.
CAD86275; CAD86275; NE2363.
KEGGineu:NE2356.
neu:NE2363.
PATRICi22716122. VBINitEur56163_2638.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AL954747 Genomic DNA. Translation: CAD86268.1.
AL954747 Genomic DNA. Translation: CAD86275.1.
RefSeqiNP_842353.1. NC_004757.1.
NP_842358.1. NC_004757.1.
WP_011112836.1. NC_004757.1.

3D structure databases

ProteinModelPortaliQ81ZS7.
SMRiQ81ZS7. Positions 9-553.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi228410.NE2363.

Proteomic databases

PRIDEiQ81ZS7.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAD86268; CAD86268; NE2356.
CAD86275; CAD86275; NE2363.
KEGGineu:NE2356.
neu:NE2363.
PATRICi22716122. VBINitEur56163_2638.

Phylogenomic databases

eggNOGiCOG0008.
HOGENOMiHOG000259232.
KOiK01886.
OMAiVTHSICT.
OrthoDBiEOG6DRPF7.
PhylomeDBiQ81ZS7.

Enzyme and pathway databases

BioCyciNEUR228410:GJNO-2401-MONOMER.
NEUR228410:GJNO-2408-MONOMER.

Family and domain databases

Gene3Di1.10.1160.10. 1 hit.
2.40.240.10. 2 hits.
3.40.50.620. 2 hits.
HAMAPiMF_00126. Gln_tRNA_synth.
InterProiIPR004514. Gln-tRNA-synth.
IPR022861. Gln_tRNA_ligase_bac.
IPR000924. Glu/Gln-tRNA-synth.
IPR020061. Glu/Gln-tRNA-synth_Ib_a-bdl.
IPR020058. Glu/Gln-tRNA-synth_Ib_cat-dom.
IPR020059. Glu/Gln-tRNA-synth_Ib_codon-bd.
IPR020056. Rbsml_L25/Gln-tRNA_synth_b-brl.
IPR011035. Ribosomal_L25/Gln-tRNA_synth.
IPR014729. Rossmann-like_a/b/a_fold.
[Graphical view]
PANTHERiPTHR10119. PTHR10119. 1 hit.
PfamiPF00749. tRNA-synt_1c. 1 hit.
PF03950. tRNA-synt_1c_C. 1 hit.
[Graphical view]
PRINTSiPR00987. TRNASYNTHGLU.
SUPFAMiSSF50715. SSF50715. 1 hit.
TIGRFAMsiTIGR00440. glnS. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Complete genome sequence of the ammonia-oxidizing bacterium and obligate chemolithoautotroph Nitrosomonas europaea."
    Chain P., Lamerdin J.E., Larimer F.W., Regala W., Lao V., Land M.L., Hauser L., Hooper A.B., Klotz M.G., Norton J., Sayavedra-Soto L.A., Arciero D.M., Hommes N.G., Whittaker M.M., Arp D.J.
    J. Bacteriol. 185:2759-2773(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 19718 / NBRC 14298.

Entry informationi

Entry nameiSYQ_NITEU
AccessioniPrimary (citable) accession number: Q81ZS7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: April 26, 2004
Last sequence update: June 1, 2003
Last modified: April 1, 2015
This is version 73 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.