Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q81ZQ9 (Q81ZQ9_TROWT) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 53. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ppa EMBL AAO44251.1
Synonyms:ppa1 HAMAP MF_00209
Ordered Locus Names:TWT154, TWT307
ORF Names:TWT_154 EMBL AAO44251.1, TWT_307 EMBL AAO44404.1
OrganismTropheryma whipplei (strain Twist) (Whipple's bacillus) [Complete proteome] [HAMAP]
Taxonomic identifier203267 [NCBI]
Taxonomic lineageBacteria › Actinobacteria › Actinobacteridae › Actinomycetales › Micrococcineae › Tropheryma

Protein attributes

Sequence length164 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209 EMBL AAO44251.1
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequences

Sequence LengthMass (Da)Tools
Q81ZQ9 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 525B4231A8D4FC24

FASTA16418,592
        10         20         30         40         50         60 
MVRLRMQTLT AIVEIPRGSR SKYEIDKKTG RLFLDRVVST AFGYPTNYGF IENTLALDGD 

        70         80         90        100        110        120 
PIDALILVQN QLFPGVALHI RPVGVLHMTD DGGEDDKVLC VALKDPYCDH INDLDDVPKH 

       130        140        150        160 
VLNQIEHFFQ HYKDLEEGKW VKLGAWNGKD KAIEIITEGL SRFN

« Hide

References

[1]"Tropheryma whipplei twist: a human pathogenic Actinobacteria with a reduced genome."
Raoult D., Ogata H., Audic S., Robert C., Suhre K., Drancourt M., Claverie J.-M.
Genome Res. 13:1800-1809(2003) [PubMed: 12902375] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE014184 Genomic DNA. Translation: AAO44251.1.
AE014184 Genomic DNA. Translation: AAO44404.1.
RefSeqNP_787282.1. NC_004572.3.
NP_787435.1. NC_004572.3.

3D structure databases

HSSPHSSP built from PDB template 1FAJ based on UniProtKB P17288.
ProteinModelPortalQ81ZQ9.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ81ZQ9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID1089560.
1482419.
GenomeReviewsGene locus TWT154 in contig AE014184_GR.
Gene locus TWT307 in contig AE014184_GR.
KEGGtwh:TWT154.
twh:TWT307.
PATRIC23996641. VBITroWhi72342_0209.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0221.
HOGENOMHBG529150.
OMAYGFFENT.
PhylomeDBQ81ZQ9.
ProtClustDBCLSK229788.

Enzyme and pathway databases

BioCycTWHI203267:TW154-MONOMER.
TWHI203267:TW307-MONOMER.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ81ZQ9_TROWT
AccessionPrimary (citable) accession number: Q81ZQ9
Entry history
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: January 25, 2012
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequences·References·Cross-refs·Entry info