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Q81ZH7

- Q81ZH7_BACAN

UniProt

Q81ZH7 - Q81ZH7_BACAN

Protein
Submitted name:

Phosphoribosylaminoimidazole carboxylase, ATPase subunit

Gene

purK

Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 1 out of 5- Protein predictedi
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    • History
      Entry version 108 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    GO - Molecular functioni

    1. ATP binding Source: UniProtKB-KW
    2. cofactor binding Source: InterPro
    3. metal ion binding Source: InterPro
    4. oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor Source: InterPro
    5. phosphoribosylaminoimidazole carboxylase activity Source: UniProtKB-EC

    GO - Biological processi

    1. 'de novo' IMP biosynthetic process Source: InterPro

    Keywords - Molecular functioni

    LyaseImported

    Keywords - Biological processi

    Purine biosynthesisSAAS annotation

    Keywords - Ligandi

    ATP-bindingSAAS annotation, Nucleotide-binding

    Enzyme and pathway databases

    BioCyciANTHRA:PURK-MONOMER.
    BANT260799:GJAJ-318-MONOMER.
    BANT261594:GJ7F-327-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Phosphoribosylaminoimidazole carboxylase, ATPase subunitImported (EC:4.1.1.21Imported)
    Gene namesi
    Name:purKImported
    Ordered Locus Names:BA_0289Imported, BAS0276Imported, GBAA_0289Imported
    OrganismiBacillus anthracisImported
    Taxonomic identifieri1392 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000000594: Chromosome, UP000000427: Chromosome, UP000005639: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi198094.BA_0289.

    Family & Domainsi

    Sequence similaritiesi

    Contains ATP-grasp domain.SAAS annotation

    Phylogenomic databases

    HOGENOMiHOG000034029.
    KOiK01589.
    OMAiDCILEGW.
    OrthoDBiEOG6QZMX7.

    Family and domain databases

    Gene3Di3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.20. 1 hit.
    InterProiIPR005875. AIR_COase_ATPase-su.
    IPR011761. ATP-grasp.
    IPR003135. ATP-grasp_carboxylate-amine.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016185. PreATP-grasp_dom.
    IPR011054. Rudment_hybrid_motif.
    [Graphical view]
    PfamiPF02826. 2-Hacid_dh_C. 1 hit.
    PF02222. ATP-grasp. 1 hit.
    [Graphical view]
    SUPFAMiSSF51246. SSF51246. 1 hit.
    SSF52440. SSF52440. 1 hit.
    TIGRFAMsiTIGR01161. purK. 1 hit.
    PROSITEiPS50975. ATP_GRASP. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q81ZH7-1 [UniParc]FASTAAdd to Basket

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    MTRIILPGKT IGIIGGGQLG RMMALAAKEM GYKIAVLDPT KNSPCAQVAD    50
    IEIVASYDDL KAIQHLAEIS DVVTYEFENI DYRCLQWLEK HAYLPQGSQL 100
    LSKTQNRFTE KNAIEKAGLP VATYRLVQNQ EQLTEAIAEL SYPSVLKTTT 150
    GGYDGKGQVV LRSEADVDEA RKLANAAECI LEKWVPFEKE VSVIVIRSVS 200
    GETKVFPVAE NIHVNNILHE SIVPARITEE LSQKAIAYAK VLADELELVG 250
    TLAVEMFATA DGEIYINELA PRPHNSGHYT QDACETSQFG QHIRAICNLP 300
    LGETNLLKPV VMVNILGEHI EGVLRQVNRL TGCYLHLYGK EEAKAQRKMG 350
    HVNILNDNIE VALEKAKSLH IWDHQEQLLE GKR 383
    Length:383
    Mass (Da):42,517
    Last modified:June 1, 2003 - v1
    Checksum:iBE0E5E1A56F88287
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016879 Genomic DNA. Translation: AAP24325.1.
    AE017334 Genomic DNA. Translation: AAT29376.2.
    AE017225 Genomic DNA. Translation: AAT52607.1.
    RefSeqiNP_842839.1. NC_003997.3.
    YP_016901.2. NC_007530.2.
    YP_026556.1. NC_005945.1.

    Genome annotation databases

    EnsemblBacteriaiAAP24325; AAP24325; BA_0289.
    AAT29376; AAT29376; GBAA_0289.
    AAT52607; AAT52607; BAS0276.
    GeneIDi1085688.
    2817202.
    2851232.
    KEGGiban:BA_0289.
    bar:GBAA_0289.
    bat:BAS0276.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016879 Genomic DNA. Translation: AAP24325.1 .
    AE017334 Genomic DNA. Translation: AAT29376.2 .
    AE017225 Genomic DNA. Translation: AAT52607.1 .
    RefSeqi NP_842839.1. NC_003997.3.
    YP_016901.2. NC_007530.2.
    YP_026556.1. NC_005945.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198094.BA_0289.

    Protocols and materials databases

    DNASUi 1085688.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP24325 ; AAP24325 ; BA_0289 .
    AAT29376 ; AAT29376 ; GBAA_0289 .
    AAT52607 ; AAT52607 ; BAS0276 .
    GeneIDi 1085688.
    2817202.
    2851232.
    KEGGi ban:BA_0289.
    bar:GBAA_0289.
    bat:BAS0276.

    Phylogenomic databases

    HOGENOMi HOG000034029.
    KOi K01589.
    OMAi DCILEGW.
    OrthoDBi EOG6QZMX7.

    Enzyme and pathway databases

    BioCyci ANTHRA:PURK-MONOMER.
    BANT260799:GJAJ-318-MONOMER.
    BANT261594:GJ7F-327-MONOMER.

    Family and domain databases

    Gene3Di 3.30.1490.20. 1 hit.
    3.30.470.20. 1 hit.
    3.40.50.20. 1 hit.
    InterProi IPR005875. AIR_COase_ATPase-su.
    IPR011761. ATP-grasp.
    IPR003135. ATP-grasp_carboxylate-amine.
    IPR013815. ATP_grasp_subdomain_1.
    IPR013816. ATP_grasp_subdomain_2.
    IPR006140. D-isomer_DH_NAD-bd.
    IPR016185. PreATP-grasp_dom.
    IPR011054. Rudment_hybrid_motif.
    [Graphical view ]
    Pfami PF02826. 2-Hacid_dh_C. 1 hit.
    PF02222. ATP-grasp. 1 hit.
    [Graphical view ]
    SUPFAMi SSF51246. SSF51246. 1 hit.
    SSF52440. SSF52440. 1 hit.
    TIGRFAMsi TIGR01161. purK. 1 hit.
    PROSITEi PS50975. ATP_GRASP. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
      Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
      , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
      Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AmesImported and Ames ancestor.
    2. "Complete genome sequence of Bacillus anthracis Sterne."
      Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
      Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: SterneImported.
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ames / isolate PortonImported, Ames AncestorImported, Ames ancestorImported and Sterne.
    4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
      Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: AmesImported.

    Entry informationi

    Entry nameiQ81ZH7_BACAN
    AccessioniPrimary (citable) accession number: Q81ZH7
    Secondary accession number(s): E9QVL4
    , E9QVL5, Q6I4C4, Q6KY26
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 108 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3