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Q81ZH6

- Q81ZH6_BACAN

UniProt

Q81ZH6 - Q81ZH6_BACAN

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Protein
Submitted name:

Adenylosuccinate lyase

Gene
purB, BA_0290, BAS0277, GBAA_0290
Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 1 out of 5 - Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

  1. (S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC
  2. N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Source: UniProtKB-EC

GO - Biological processi

  1. purine ribonucleotide biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

LyaseImported

Enzyme and pathway databases

BioCyciANTHRA:PURB-MONOMER.
BANT260799:GJAJ-319-MONOMER.
BANT261594:GJ7F-328-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Adenylosuccinate lyaseImported (EC:4.3.2.2Imported)
Gene namesi
Name:purBImported
Ordered Locus Names:BA_0290Imported, BAS0277Imported, GBAA_0290Imported
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000005639: Chromosome, UP000000427: Chromosome, UP000000594: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_0290.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
2PFMX-ray2.00A/B1-435[»]

Miscellaneous databases

EvolutionaryTraceiQ81ZH6.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000033912.
KOiK01756.
OMAiERIIEDK.
OrthoDBiEOG686NDB.

Family and domain databases

Gene3Di1.10.275.10. 1 hit.
InterProiIPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view]
PANTHERiPTHR11444. PTHR11444. 1 hit.
PfamiPF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]
PRINTSiPR00149. FUMRATELYASE.
SMARTiSM00998. ADSL_C. 1 hit.
[Graphical view]
SUPFAMiSSF48557. SSF48557. 1 hit.
TIGRFAMsiTIGR00928. purB. 1 hit.
PROSITEiPS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81ZH6-1 [UniParc]FASTAAdd to Basket

« Hide

MISRYTRPEM GAIWTEENKF KAWLEVEILA CEAWAELGDI PKEDVKKIRE    50
HASFDIDRIY EIEKETRHDV VAFTRAVSET PALGEERKWV HYGLTSTDVV 100
DTALSYILKQ ANEIILKDLE NFVSILANKA KEHKYTIMMG RTHGVHAEPT 150
TFGLKLGLWY EEMKRNVERF KQAANTVRVG KLSGAVGTYA NIDPFVEKYV 200
CENLGLEAAP ISTQTLQRDR HAHYMSTLAL IATSIEKMAV EIRGLQKSET 250
REVEEAFAKG QKGSSAMPHK RNPIGSENMT GLARVIRGYM MTAYENVPLW 300
HERDISHSSA ERVILPDATI ALNYMLNRFG NIVKNLTVYP ENMKRNMTRT 350
YGLIYSQRVM LTLIDKGMVR EEAYDIVQPK AMEAWETQVQ FKELVEADER 400
ITSKLTQEEI NECFNYEHHM QHVDTIFERL GLNEA 435
Length:435
Mass (Da):49,988
Last modified:June 1, 2003 - v1
Checksum:i772B8EB811E0CB98
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP24326.1.
AE017334 Genomic DNA. Translation: AAT29377.1.
AE017225 Genomic DNA. Translation: AAT52608.1.
RefSeqiNP_842840.1. NC_003997.3.
YP_016902.1. NC_007530.2.
YP_026557.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP24326; AAP24326; BA_0290.
AAT29377; AAT29377; GBAA_0290.
AAT52608; AAT52608; BAS0277.
GeneIDi1085703.
2819273.
2850059.
KEGGiban:BA_0290.
bar:GBAA_0290.
bat:BAS0277.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP24326.1 .
AE017334 Genomic DNA. Translation: AAT29377.1 .
AE017225 Genomic DNA. Translation: AAT52608.1 .
RefSeqi NP_842840.1. NC_003997.3.
YP_016902.1. NC_007530.2.
YP_026557.1. NC_005945.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
2PFM X-ray 2.00 A/B 1-435 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198094.BA_0290.

Protocols and materials databases

DNASUi 1085703.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP24326 ; AAP24326 ; BA_0290 .
AAT29377 ; AAT29377 ; GBAA_0290 .
AAT52608 ; AAT52608 ; BAS0277 .
GeneIDi 1085703.
2819273.
2850059.
KEGGi ban:BA_0290.
bar:GBAA_0290.
bat:BAS0277.

Phylogenomic databases

HOGENOMi HOG000033912.
KOi K01756.
OMAi ERIIEDK.
OrthoDBi EOG686NDB.

Enzyme and pathway databases

BioCyci ANTHRA:PURB-MONOMER.
BANT260799:GJAJ-319-MONOMER.
BANT261594:GJ7F-328-MONOMER.

Miscellaneous databases

EvolutionaryTracei Q81ZH6.

Family and domain databases

Gene3Di 1.10.275.10. 1 hit.
InterProi IPR019468. AdenyloSucc_lyase_C.
IPR024083. Fumarase/histidase_N.
IPR020557. Fumarate_lyase_CS.
IPR000362. Fumarate_lyase_fam.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view ]
PANTHERi PTHR11444. PTHR11444. 1 hit.
Pfami PF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view ]
PRINTSi PR00149. FUMRATELYASE.
SMARTi SM00998. ADSL_C. 1 hit.
[Graphical view ]
SUPFAMi SSF48557. SSF48557. 1 hit.
TIGRFAMsi TIGR00928. purB. 1 hit.
PROSITEi PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolsto A.B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate Porton.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. "Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis."
    Levdikov V.M., Blagova E.V., Wilkinson A.J., Wilson K.S.
    Submitted (APR-2007) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
  4. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestor.
  5. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.

Entry informationi

Entry nameiQ81ZH6_BACAN
AccessioniPrimary (citable) accession number: Q81ZH6
Secondary accession number(s): E9RC82
, E9RC83, Q6I4C3, Q6KY25
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: September 3, 2014
This is version 107 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteome

External Data

Dasty 3

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