Q81ZH6 (Q81ZH6_BACAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Adenylosuccinate lyase EMBL AAP24326.1
EC=4.3.2.2 EMBL AAT29377.1

Gene names

Name:	purB EMBL AAP24326.1
Ordered Locus Names:	BA_0290 EMBL AAP24326.1, BAS0277 EMBL AAT52608.1, GBAA_0290 EMBL AAT29377.1

Organism

Bacillus anthracis [Reference proteome] [HAMAP]

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	435 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Lyase EMBL AAP24326.1
Technical term	3D-structure PDB 2PFM Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	purine ribonucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular_function	(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido)succinate AMP-lyase (fumarate-forming) activity Inferred from electronic annotation. Source: EC N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q81ZH6 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 772B8EB811E0CB98	FASTA	435	49,988
	10 20 30 40 50 60 MISRYTRPEM GAIWTEENKF KAWLEVEILA CEAWAELGDI PKEDVKKIRE HASFDIDRIY 70 80 90 100 110 120 EIEKETRHDV VAFTRAVSET PALGEERKWV HYGLTSTDVV DTALSYILKQ ANEIILKDLE 130 140 150 160 170 180 NFVSILANKA KEHKYTIMMG RTHGVHAEPT TFGLKLGLWY EEMKRNVERF KQAANTVRVG 190 200 210 220 230 240 KLSGAVGTYA NIDPFVEKYV CENLGLEAAP ISTQTLQRDR HAHYMSTLAL IATSIEKMAV 250 260 270 280 290 300 EIRGLQKSET REVEEAFAKG QKGSSAMPHK RNPIGSENMT GLARVIRGYM MTAYENVPLW 310 320 330 340 350 360 HERDISHSSA ERVILPDATI ALNYMLNRFG NIVKNLTVYP ENMKRNMTRT YGLIYSQRVM 370 380 390 400 410 420 LTLIDKGMVR EEAYDIVQPK AMEAWETQVQ FKELVEADER ITSKLTQEEI NECFNYEHHM 430 QHVDTIFERL GLNEA

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames EMBL AAP24326.1 and Ames / isolate Porton.
[2]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne EMBL AAT52608.1.
[3]	"Crystal Structure of Adenylosuccinate Lyase (PurB) from Bacillus anthracis." Levdikov V.M., Blagova E.V., Wilkinson A.J., Wilson K.S. Submitted (APR-2007) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
[4]	"The complete genome sequence of Bacillus anthracis Ames "Ancestor"." Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A. J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor and Ames Ancestor EMBL AAT29377.1.
[5]	Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Ames EMBL AAP24326.1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE016879 Genomic DNA. Translation: AAP24326.1.
AE017334 Genomic DNA. Translation: AAT29377.1.
AE017225 Genomic DNA. Translation: AAT52608.1.

RefSeq

NP_842840.1. NC_003997.3.
YP_016902.1. NC_007530.2.
YP_026557.1. NC_005945.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
2PFM	X-ray	2.00	A/B	1-435	[»]

SMR

Q81ZH6. Positions 2-435.

ModBase

Search...

Protein-protein interaction databases

STRING

198094.BA_0290.

Protocols and materials databases

DNASU

1085703.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAP24326; AAP24326; BA_0290.
AAT29377; AAT29377; GBAA_0290.
AAT52608; AAT52608; BAS0277.

GeneID

1085703.
2819273.
2850059.

KEGG

ban:BA_0290.
bar:GBAA_0290.
bat:BAS0277.

Phylogenomic databases

HOGENOM

HOG000033912.

KO

K01756.

OMA

AAKTIWE.

ProtClustDB

PRK08937.

Enzyme and pathway databases

BioCyc

BANT260799:GJAJ-319-MONOMER.
BANT261594:GJ7F-328-MONOMER.

Family and domain databases

Gene3D

1.10.275.10. 1 hit.

InterPro

IPR019468. AdenyloSucc_lyase_C.
IPR003031. D_crystallin.
IPR024083. Fumarase/histidase_N.
IPR000362. Fumarate_lyase.
IPR020557. Fumarate_lyase_CS.
IPR022761. Fumarate_lyase_N.
IPR008948. L-Aspartase-like.
IPR004769. Pur_lyase.
[Graphical view]

PANTHER

PTHR11444:SF2. PTHR11444:SF2. 1 hit.

Pfam

PF10397. ADSL_C. 1 hit.
PF00206. Lyase_1. 1 hit.
[Graphical view]

PRINTS

PR00145. ARGSUCLYASE.
PR00149. FUMRATELYASE.

SMART

SM00998. ADSL_C. 1 hit.
[Graphical view]

SUPFAM

SSF48557. L-Aspartase-like. 1 hit.

TIGRFAMs

TIGR00928. purB. 1 hit.

PROSITE

PS00163. FUMARATE_LYASES. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q81ZH6.

Entry information

Entry name

Q81ZH6_BACAN

Accession

Primary (citable) accession number: Q81ZH6
Secondary accession number(s): E9RC82 , E9RC83, Q6I4C3, Q6KY25

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 94 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)