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Protein
Submitted name:

4-aminobutyrate aminotransferase

Gene

gabT

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. 4-aminobutyrate transaminase activity Source: UniProtKB-EC
  2. pyridoxal phosphate binding Source: InterPro

GO - Biological processi

  1. gamma-aminobutyric acid metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

AminotransferaseImported, Transferase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Enzyme and pathway databases

BioCyciANTHRA:GABT-MONOMER.
BANT260799:GJAJ-352-MONOMER.
BANT261594:GJ7F-362-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
4-aminobutyrate aminotransferaseImported (EC:2.6.1.19Imported)
Submitted name:
4-aminobutyrate transaminaseImported (EC:2.6.1.19Imported)
Gene namesi
Name:gabTImported
Ordered Locus Names:BA_0325Imported, BAS0310Imported, GBAA_0325Imported
ORF Names:DJ42_4766Imported, DJ43_4871Imported, DJ44_4185Imported, DJ45_5562Imported, DJ49_5170Imported, NX97_02105Imported, OY21_21235Imported, OY22_04810Imported, OY23_03195Imported, OY24_20315Imported, OY25_00840Imported, OY27_03470Imported, OY28_09040Imported, OY29_02015Imported, OY30_03635Imported, OY32_02380Imported, OY34_01155Imported, OY35_02315Imported, OY36_06685Imported, OY37_01450Imported, OY38_08495Imported, OY39_03120Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_0325.

Structurei

3D structure databases

ProteinModelPortaliQ81ZE4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK07250.
OMAiNLCAEAN.
OrthoDBiEOG6QVRHN.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81ZE4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNTKKFAKVN EQIPGPKAAS LLERRQNIVP KGVSNGIPTF VQSANGALVT
60 70 80 90 100
DVDGNQYIDF AGAIGTINVG HCHPAVKEAL HKQVDQYIHT GFNVMMYEPY
110 120 130 140 150
IELAEKLAAL APGSFDKQVL FLNSGAEAVE NAVKIARKYT KRPGIIAFSK
160 170 180 190 200
GFHGRTLMTM TMTSKVKPYK FGFGPFAPEV YKAPFPYEYR CPEGLTEEQY
210 220 230 240 250
DDFMIEEFKN FFISEVAPET IAAVVMEPVQ GEGGFIVPSK KFAQEVRNIC
260 270 280 290 300
SEHGILFVAD EIQTGFSRTG KYFAIDHYDV VPDLITVSKS LGAGVPISGV
310 320 330 340 350
IGRKEIMNES APGELGGTYA GSPLGCAAAL AVLDVIEKEN LNDRAIELGK
360 370 380 390 400
VVMNRFEEMK NKYNCIGDVR GLGAMCAFEL VQDRKTKTPD KTLTANLCTE
410 420 430 440 450
ANKRGLLLLS AGTYGNVIRV LMPLVITDEQ LEEGLTIIEE SLQICYEKAN

TARV
Length:454
Mass (Da):49,707
Last modified:June 1, 2003 - v1
Checksum:iBA936DE91B764C72
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP24358.1.
AE017334 Genomic DNA. Translation: AAT29416.1.
AE017225 Genomic DNA. Translation: AAT52641.1.
CP008752 Genomic DNA. Translation: AIK54008.1.
CP007704 Genomic DNA. Translation: AIK56716.1.
JNOD01000011 Genomic DNA. Translation: KFJ82874.1.
JMPV01000005 Genomic DNA. Translation: KFL76936.1.
JMPU01000011 Genomic DNA. Translation: KFL79439.1.
JTAQ01000029 Genomic DNA. Translation: KGZ45720.1.
JTAR01000018 Genomic DNA. Translation: KGZ54522.1.
JTAS01000005 Genomic DNA. Translation: KGZ57338.1.
JSZQ01000042 Genomic DNA. Translation: KGZ65812.1.
JSZR01000003 Genomic DNA. Translation: KGZ72819.1.
JSZP01000012 Genomic DNA. Translation: KGZ73105.1.
JSZU01000021 Genomic DNA. Translation: KGZ86712.1.
JSZT01000017 Genomic DNA. Translation: KGZ88817.1.
JSZW01000031 Genomic DNA. Translation: KHA04047.1.
JSZV01000006 Genomic DNA. Translation: KHA05689.1.
JSZY01000010 Genomic DNA. Translation: KHA07807.1.
JTAA01000004 Genomic DNA. Translation: KHA19426.1.
JTAB01000008 Genomic DNA. Translation: KHA20350.1.
JTAC01000022 Genomic DNA. Translation: KHA27081.1.
JTAE01000015 Genomic DNA. Translation: KHA34246.1.
JTAD01000006 Genomic DNA. Translation: KHA34319.1.
JTAF01000014 Genomic DNA. Translation: KHA44032.1.
RefSeqiNP_842872.1. NC_003997.3.
YP_016941.1. NC_007530.2.
YP_026590.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP24358; AAP24358; BA_0325.
AAT29416; AAT29416; GBAA_0325.
AAT52641; AAT52641; BAS0310.
GeneIDi1086502.
2816571.
2849321.
KEGGiban:BA_0325.
bar:GBAA_0325.
bat:BAS0310.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP24358.1.
AE017334 Genomic DNA. Translation: AAT29416.1.
AE017225 Genomic DNA. Translation: AAT52641.1.
CP008752 Genomic DNA. Translation: AIK54008.1.
CP007704 Genomic DNA. Translation: AIK56716.1.
JNOD01000011 Genomic DNA. Translation: KFJ82874.1.
JMPV01000005 Genomic DNA. Translation: KFL76936.1.
JMPU01000011 Genomic DNA. Translation: KFL79439.1.
JTAQ01000029 Genomic DNA. Translation: KGZ45720.1.
JTAR01000018 Genomic DNA. Translation: KGZ54522.1.
JTAS01000005 Genomic DNA. Translation: KGZ57338.1.
JSZQ01000042 Genomic DNA. Translation: KGZ65812.1.
JSZR01000003 Genomic DNA. Translation: KGZ72819.1.
JSZP01000012 Genomic DNA. Translation: KGZ73105.1.
JSZU01000021 Genomic DNA. Translation: KGZ86712.1.
JSZT01000017 Genomic DNA. Translation: KGZ88817.1.
JSZW01000031 Genomic DNA. Translation: KHA04047.1.
JSZV01000006 Genomic DNA. Translation: KHA05689.1.
JSZY01000010 Genomic DNA. Translation: KHA07807.1.
JTAA01000004 Genomic DNA. Translation: KHA19426.1.
JTAB01000008 Genomic DNA. Translation: KHA20350.1.
JTAC01000022 Genomic DNA. Translation: KHA27081.1.
JTAE01000015 Genomic DNA. Translation: KHA34246.1.
JTAD01000006 Genomic DNA. Translation: KHA34319.1.
JTAF01000014 Genomic DNA. Translation: KHA44032.1.
RefSeqiNP_842872.1. NC_003997.3.
YP_016941.1. NC_007530.2.
YP_026590.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81ZE4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198094.BA_0325.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP24358; AAP24358; BA_0325.
AAT29416; AAT29416; GBAA_0325.
AAT52641; AAT52641; BAS0310.
GeneIDi1086502.
2816571.
2849321.
KEGGiban:BA_0325.
bar:GBAA_0325.
bat:BAS0310.

Phylogenomic databases

HOGENOMiHOG000020206.
KOiK07250.
OMAiNLCAEAN.
OrthoDBiEOG6QVRHN.

Enzyme and pathway databases

BioCyciANTHRA:GABT-MONOMER.
BANT260799:GJAJ-352-MONOMER.
BANT261594:GJ7F-362-MONOMER.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
3.90.1150.10. 1 hit.
InterProiIPR004632. 4NH2But_aminotransferase_bac.
IPR005814. Aminotrans_3.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
IPR015422. PyrdxlP-dep_Trfase_major_sub2.
[Graphical view]
PANTHERiPTHR11986. PTHR11986. 1 hit.
PfamiPF00202. Aminotran_3. 1 hit.
[Graphical view]
PIRSFiPIRSF000521. Transaminase_4ab_Lys_Orn. 1 hit.
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR00700. GABAtrnsam. 1 hit.
PROSITEiPS00600. AA_TRANSFER_CLASS_3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate PortonImported.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A.Br.003Imported, Smith 1013Imported and Zimbabwe 89Imported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BFVImported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Delta SterneImported.
  8. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031027Imported.
  9. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C.A., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031006Imported, 2000031023Imported, 2000031031Imported, 2000031038Imported, 2000031039Imported, 2000031075Imported, 2000031709Imported, 2000031765Imported, 2000032819Imported, 2000032879Imported, 2000032951Imported, 2000032967Imported, 2000032968Imported, 2000032975Imported, 2000032979Imported and 2000032989Imported.

Entry informationi

Entry nameiQ81ZE4_BACAN
AccessioniPrimary (citable) accession number: Q81ZE4
Secondary accession number(s): E9QV97
, E9QV98, Q6I490, Q6KXZ6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 4, 2015
This is version 97 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.