Q81ZB7 (FENR1_BACAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ferredoxin--NADP reductase 1
Short name=FNR 1
Short name=Fd-NADP+ reductase 1
EC=1.18.1.2

Gene names

Ordered Locus Names:

BA_0352, GBAA_0352, BAS0337

Organism

Bacillus anthracis

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	349 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	2 reduced ferredoxin + NADP+ + H+ = 2 oxidized ferredoxin + NADPH. HAMAP MF_01685
Cofactor	Binds 1 FAD per subunit By similarity. HAMAP MF_01685
Subunit structure	Homodimer By similarity. HAMAP MF_01685
Sequence similarities	Belongs to the ferredoxin--NADP reductase type 2 family.

Ontologies

Keywords
Ligand	FAD Flavoprotein NADP
Molecular function	Oxidoreductase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular function	ferredoxin-NADP+ reductase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 349	349	Ferredoxin--NADP reductase 1 HAMAP MF_01685		PRO_0000364786
Sites
	Binding site	36	1	FAD By similarity
	Binding site	44	1	FAD By similarity
	Binding site	48	1	FAD By similarity
	Binding site	88	1	FAD; via amide nitrogen and carbonyl oxygen By similarity
	Binding site	123	1	FAD; via amide nitrogen By similarity
	Binding site	290	1	FAD By similarity
	Binding site	331	1	FAD By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q81ZB7 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: A6AE7F16F2AD131F	FASTA	349	38,690
	10 20 30 40 50 60 MNREELFDVT VIGGGPAGLY SAFYSGLREM KTKIIEFQPQ LGGKIHVYPE KMIWDIGGLL 70 80 90 100 110 120 PVTGEKLIEQ LVQQGLTFQP EVVLNTKIES IIRNKDGIFT LKTSTGEEHF SKTVIVATGS 130 140 150 160 170 180 GILNPQKLSI EGAERFEVSN LNYTVKSLKR FKNKTVIISG GGNSAIDWAN ELEPIAKKVY 190 200 210 220 230 240 LTYRKEELSG HEAQVKQLMN SSAECFFNTS ITTLIAGDNH EAIEYVELTN HETGEVSQLA 250 260 270 280 290 300 IDEVIINHGY ERDITLLENS ELDVAIIDNY YIAGNANSES SVDGLYAAGD ILKHEGKLHL 310 320 330 340 IAGAFQDAGN AVNKAKQFIQ PDASEYGMVS SHNEVFKKRN RELIKQMMK

References

[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton.
[2]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne.
[3]	"Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016879 Genomic DNA. Translation: AAP24385.1. AE017334 Genomic DNA. Translation: AAT29443.1. AE017225 Genomic DNA. Translation: AAT52668.1.
RefSeq	NP_842899.1. NC_003997.3. YP_016968.1. NC_007530.2. YP_026617.1. NC_005945.1.
3D structure databases
ProteinModelPortal	Q81ZB7.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000011691; EBBACP00000011447; EBBACG00000011683. EBBACT00000018195; EBBACP00000017816; EBBACG00000018186. EBBACT00000024378; EBBACP00000023863; EBBACG00000024369.
GeneID	1084697. 2817656. 2848615.
GenomeReviews	Gene locus BA_0352 in contig AE016879_GR. Gene locus BAS0337 in contig AE017225_GR. Gene locus GBAA_0352 in contig AE017334_GR.
KEGG	ban:BA_0352. bar:GBAA_0352. bat:BAS0337.
TIGR	BA_0352. GBAA_0352.
Phylogenomic databases
GeneTree	EBGT00050000000432.
HOGENOM	HBG669726.
OMA	FNTSITK.
ProtClustDB	CLSK904552.
Enzyme and pathway databases
BioCyc	BANT260799:BAS0337-MONOMER. BANT261594:GBAA0352-MONOMER.
Family and domain databases
HAMAP	MF_01685. FENR2. [Tree]
InterPro	IPR013027. FAD_pyr_nucl-diS_OxRdtase. IPR022890. Fd--NADP_Rdtase_type_2. IPR023753. Pyr_nucl-diS_OxRdtase_FAD/NAD. IPR000103. Pyridine_nuc-diS_OxRdtase_2. [Graphical view]
KO	K00384.
PANTHER	PTHR22912:SF53. PTHR22912:SF53. 1 hit.
Pfam	PF07992. Pyr_redox_2. 1 hit. [Graphical view]
PRINTS	PR00368. FADPNR. PR00469. PNDRDTASEII.
ProtoNet	Search...

Entry information

Entry name

FENR1_BACAN

Accession

Primary (citable) accession number: Q81ZB7
Secondary accession number(s): Q6I463, Q6KXW9

Entry history

Integrated into UniProtKB/Swiss-Prot:	March 3, 2009
Last sequence update:	June 1, 2003
Last modified:	November 16, 2011
This is version 76 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program