<p>Provides any useful information about the protein, mostly biological knowledge.</p><p><a href='../manual/function_section' target='_top'>More...</a></p>Functionⁱ

Sites

Feature key	Position(s)	Length	Description	Graphical view	Feature identifier	Actions
<p>Is used for enzymes and indicates the residues directly involved in catalysis.</p><p><a href='../manual/act_site' target='_top'>More...</a></p>Active sitei	261 – 261	1	NucleophileUniRule annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000256">More…</a></p> Automatic assertion according to rulesi PIRSR:PIRSR001021-1
<p>Is used for enzymes and indicates the residues directly involved in catalysis.</p><p><a href='../manual/act_site' target='_top'>More...</a></p>Active sitei	291 – 291	1	Proton donorUniRule annotation <p>Information which has been generated by the UniProtKB automatic annotation system, without manual validation.</p> <p><a href="/manual/evidences#ECO:0000256">More…</a></p> Automatic assertion according to rulesi PIRSR:PIRSR001021-1

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Molecular functionⁱ

1. alpha-amylase activity Source: UniProtKB-EC
2. calcium ion binding Source: InterPro

<p>The <a href="http://www.geneontology.org/">Gene Ontology (GO)</a> project provides a set of hierarchical controlled vocabulary split into 3 categories:</p><p><a href='../manual/gene_ontology' target='_top'>More...</a></p>GO - Biological processⁱ

1. carbohydrate metabolic process Source: InterPro

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Molecular functionⁱ

Enzyme and pathway databases

Protein family/group databases

<p>Provides information about the protein and gene name(s) and synonym(s) and about the organism that is the source of the protein sequence.</p><p><a href='../manual/names_and_taxonomy_section' target='_top'>More...</a></p>Names & Taxonomyⁱ

<p>Provides information on the quaternary structure of a protein and on interaction(s) with other proteins or protein complexes.</p><p><a href='../manual/interaction_section' target='_top'>More...</a></p>Interactionⁱ

Protein-protein interaction databases

<p>Provides information on the tertiary structure of a protein.</p><p><a href='../manual/structure_section' target='_top'>More...</a></p>Structureⁱ

3D structure databases

<p>Provides information on sequence similarities with other proteins and the domain(s) present in a protein.</p><p><a href='../manual/family_and_domains_section' target='_top'>More...</a></p>Family & Domainsⁱ

Phylogenomic databases

Family and domain databases

<p>Displays by default the canonical protein sequence and upon request all isoforms described in the entry. It also includes information pertinent to the sequence(s), including length and molecular weight.</p><p><a href='../manual/sequences_section' target='_top'>More...</a></p>Sequenceⁱ

<p>Indicates if the canonical sequence displayed by default in the entry is complete or not.</p><p><a href='../manual/sequence_status' target='_top'>More...</a></p>Sequence statusⁱ: Complete.

        10         20         30         40         50
MFKKITIVGL SVVLFLPSIY GESKVYADTI NNGTLMQYFE WYAPSDRNHW 
        60         70         80         90        100
NRLRTDAENL AQKGITSVWI PPAYKGTTQN DVGYGAYDLY DLGEFNQKGT 
       110        120        130        140        150
VRTKYGTKAQ LKSAIEALHK QNIDVYGDVV MNHKGGADYT ETVTAVEVDR 
       160        170        180        190        200
NNRNVEVSGD YEISAWTGFN FPGRGDNYSN FKWKWYHFDG TDWDEGRKLN 
       210        220        230        240        250
RIYKFRGIGK AWDWEVSSEN GNYDYLMYAD LDFDHPDVAN EMKNWGTWYA 
       260        270        280        290        300
NELNLDGFRL DAVKHIDHEY LRDWVNHVRQ QTGKEMFTVA EYWQNDIQTL 
       310        320        330        340        350
NNYLAKVNYN QSVFDAPLHY NFHYASKGNG NYDMRNILNG TVMQNHPALA 
       360        370        380        390        400
VTLVENHDSQ PGQSLESVVS PWFKPLAYAF ILTRAEGYPS VFYGDYYGTS 
       410        420        430        440        450
GNSSYEIPAL KDKIDPILTA RKNFAYGTQR DYLDHPDVIG WTREGDSVHA 
       460        470        480        490        500
NSGLATLISD GPGGSKWMDV GKNNAGEVWH DMTGNQTNTV TINKDGWGQF 
       510 
HVSGGSVSIY VQQ                                  

Sequence databases

Genome annotation databases

<p>Is used to point to information related to entries and found in data collections other than UniProtKB.</p><p><a href='../manual/cross_references_section' target='_top'>More...</a></p>Cross-referencesⁱ

Sequence databases

3D structure databases

Protein-protein interaction databases

Protein family/group databases

Protocols and materials databases

Genome annotation databases

Phylogenomic databases

Enzyme and pathway databases

Family and domain databases

<p>Contains the literature citations that are the sources of data used to annotate the entry. Each reference is numbered and contains several subsections allowing a precise description of a given citation.</p><p><a href='../manual/publications_section' target='_top'>More...</a></p>Publicationsⁱ

1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
   Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.

   , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
   Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
   Strain: AmesImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AAP27311.1
   and Ames / isolate PortonImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • Proteomes:UP000000427
   .
   
2. "Complete genome sequence of Bacillus anthracis Sterne."
   Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
   Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
   Strain: SterneImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AAT55599.1
   • Proteomes:UP000005639
   .
   
3. "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'."
   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.
   J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract]
   Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
   Strain: Ames ancestorImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • Proteomes:UP000000594
   and Ames AncestorImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AAT32659.1
   .
   
4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
   Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE.
   Strain: AmesImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AAP27311.1
   .
   
5. Tong Y.G., Huang Y., An X.P., Li S.S., Mi Z.Q., Pei G.Q., Zhang Z.Y., Fan H.
   Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE.
   Strain: HanImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AIM12749.1
   .
   
6. Bishop-Lilly K.A., Broomall S.M., Chain P.S., Chertkov O., Coyne S.R., Daligault H.E., Davenport K.W., Erkkila T., Frey K.G., Gibbons H.S., Gu W., Jaissle J., Johnson S.L., Koroleva G.I., Ladner J.T., Lo C.-C., Minogue T.D., Munk C.

   , Palacios G.F., Redden C.L., Rosenzweig C.N., Scholz M.B., Teshima H., Xu Y.
   Submitted (APR-2014) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE.
   Strain: A.Br.003Imported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:KFL66792.1
   .
   
7. "Draft Genome Sequence of Bacillus anthracis STI."
   Okinaka R.T., Challacombe J.F., Drees K., Birdsell D.N., Janke N., Naumann A., Seymour M., O'Neill H.H., Schupp J., Sahl J., Foster J.T., Pearson T., Keim P.
   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE.
   Strain: STI-1Imported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AIK09574.1
   .
   
8. Bishop-Lilly K.A., Broomall S.M., Chain P.S., Chertkov O., Coyne S.R., Daligault H.E., Davenport K.W., Erkkila T., Frey K.G., Gibbons H.S., Gu W., Jaissle J., Johnson S.L., Koroleva G.I., Ladner J.T., Lo C.-C., Minogue T.D., Munk C.

   , Palacios G.F., Redden C.L., Rosenzweig C.N., Scholz M.B., Teshima H., Xu Y.
   Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE.
   Strain: BFVImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AIK55710.1
   .
   
9. Bishop-Lilly K.A., Broomall S.M., Chain P.S., Chertkov O., Coyne S.R., Daligault H.E., Davenport K.W., Erkkila T., Frey K.G., Gibbons H.S., Gu W., Jaissle J., Johnson S.L., Koroleva G.I., Ladner J.T., Lo C.-C., Minogue T.D., Munk C.

   , Palacios G.F., Redden C.L., Rosenzweig C.N., Scholz M.B., Teshima H., Xu Y.
   Submitted (JUN-2014) to the EMBL/GenBank/DDBJ databases
   Cited for: NUCLEOTIDE SEQUENCE.
   Strain: Delta SterneImported

   <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

   • EMBL:AIK50765.1
   .
   
10. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C.A., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031075Imported

    <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

    • EMBL:KGZ78114.1
    , 2000032879Imported

    <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

    • EMBL:KHA03417.1
    , 2000032975Imported

    <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

    • EMBL:KHA29173.1
    and 2000032979Imported

    <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

    • EMBL:KHA25743.1
    .
    
11. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031027Imported

    <p>Information which has been imported from another database using automatic procedures.</p> <p><a href="/manual/evidences#ECO:0000313">More…</a></p> Automatic assertion inferred from database entriesⁱ

    • EMBL:KGZ44342.1
    .
    

<p>Provides general information on the entry.</p><p><a href='../manual/entry_information_section' target='_top'>More...</a></p>Entry informationⁱ

<p>Contains any relevant information that doesn’t fit in any other defined sections</p><p><a href='../manual/miscellaneous_section' target='_top'>More...</a></p>Miscellaneousⁱ

<p>UniProtKB Keywords constitute a <a target="_top" href="/keywords">controlled vocabulary</a> with a hierarchical structure. Keywords summarise the content of a UniProtKB entry and facilitate the search for proteins of interest.<p><a href='../help/keywords' target='_top'>More...</a></p>Keywords - Technical termⁱ

External Data

<p>Provides links to the UniProt Reference Clusters (<a href="/help/uniref">UniRef</a>). UniRef consists of clusters for UniProtKB sequences (including isoforms) and selected UniParc sequences, in order to obtain complete coverage of the sequence space at resolutions of 100%, 90% and 50% identity.</p><p><a href='../manual/similar_proteins_section' target='_top'>More...</a></p>Similar proteinsⁱ