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Protein
Submitted name:

Alpha-amylase

Gene

amyS

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei261 – 2611NucleophileUniRule annotation
Active sitei291 – 2911Proton donorUniRule annotation

GO - Molecular functioni

  1. alpha-amylase activity Source: UniProtKB-EC
  2. calcium ion binding Source: InterPro

GO - Biological processi

  1. carbohydrate metabolic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

GlycosidaseImported, Hydrolase

Enzyme and pathway databases

BioCyciANTHRA:AMYS-MONOMER.
BANT260799:GJAJ-3353-MONOMER.
BANT261594:GJ7F-3463-MONOMER.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Names & Taxonomyi

Protein namesi
Submitted name:
Alpha-amylaseImported (EC:3.2.1.1Imported)
Submitted name:
Cytoplasmic alpha-amylaseImported
Gene namesi
Name:amySImported
Ordered Locus Names:BA_3551Imported, BAS3291Imported, GBAA_3551Imported
ORF Names:BAHan_3757Imported, DH23_3449Imported, DJ44_1696Imported, DJ45_2434Imported, DJ49_1529Imported, OY22_18860Imported, OY27_26500Imported, OY32_15410Imported, OY37_12435Imported, OY38_21095Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_3551.

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000094847.
KOiK01176.
OMAiNDGNHWN.
OrthoDBiEOG65QWH3.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015237. Alpha-amylase_C_pro.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF09154. DUF1939. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81YJ4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MFKKITIVGL SVVLFLPSIY GESKVYADTI NNGTLMQYFE WYAPSDRNHW
60 70 80 90 100
NRLRTDAENL AQKGITSVWI PPAYKGTTQN DVGYGAYDLY DLGEFNQKGT
110 120 130 140 150
VRTKYGTKAQ LKSAIEALHK QNIDVYGDVV MNHKGGADYT ETVTAVEVDR
160 170 180 190 200
NNRNVEVSGD YEISAWTGFN FPGRGDNYSN FKWKWYHFDG TDWDEGRKLN
210 220 230 240 250
RIYKFRGIGK AWDWEVSSEN GNYDYLMYAD LDFDHPDVAN EMKNWGTWYA
260 270 280 290 300
NELNLDGFRL DAVKHIDHEY LRDWVNHVRQ QTGKEMFTVA EYWQNDIQTL
310 320 330 340 350
NNYLAKVNYN QSVFDAPLHY NFHYASKGNG NYDMRNILNG TVMQNHPALA
360 370 380 390 400
VTLVENHDSQ PGQSLESVVS PWFKPLAYAF ILTRAEGYPS VFYGDYYGTS
410 420 430 440 450
GNSSYEIPAL KDKIDPILTA RKNFAYGTQR DYLDHPDVIG WTREGDSVHA
460 470 480 490 500
NSGLATLISD GPGGSKWMDV GKNNAGEVWH DMTGNQTNTV TINKDGWGQF
510
HVSGGSVSIY VQQ
Length:513
Mass (Da):58,446
Last modified:June 1, 2003 - v1
Checksum:i558D6EF282FD159B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP27311.1.
AE017334 Genomic DNA. Translation: AAT32659.1.
AE017225 Genomic DNA. Translation: AAT55599.1.
CP007660 Genomic DNA. Translation: AIK09574.1.
CP008752 Genomic DNA. Translation: AIK50765.1.
CP007704 Genomic DNA. Translation: AIK55710.1.
CP008854 Genomic DNA. Translation: AIM12749.1.
JMPV01000008 Genomic DNA. Translation: KFL66792.1.
JTAR01000047 Genomic DNA. Translation: KGZ44342.1.
JSZT01000044 Genomic DNA. Translation: KGZ78114.1.
JSZY01000046 Genomic DNA. Translation: KHA03417.1.
JTAE01000053 Genomic DNA. Translation: KHA25743.1.
JTAD01000031 Genomic DNA. Translation: KHA29173.1.
RefSeqiNP_845825.1. NC_003997.3.
WP_000473536.1. NZ_KN050651.1.
YP_020184.1. NC_007530.2.
YP_029548.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP27311; AAP27311; BA_3551.
AAT32659; AAT32659; GBAA_3551.
AAT55599; AAT55599; BAS3291.
GeneIDi1084526.
2816336.
2849079.
KEGGiban:BA_3551.
bar:GBAA_3551.
bat:BAS3291.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP27311.1.
AE017334 Genomic DNA. Translation: AAT32659.1.
AE017225 Genomic DNA. Translation: AAT55599.1.
CP007660 Genomic DNA. Translation: AIK09574.1.
CP008752 Genomic DNA. Translation: AIK50765.1.
CP007704 Genomic DNA. Translation: AIK55710.1.
CP008854 Genomic DNA. Translation: AIM12749.1.
JMPV01000008 Genomic DNA. Translation: KFL66792.1.
JTAR01000047 Genomic DNA. Translation: KGZ44342.1.
JSZT01000044 Genomic DNA. Translation: KGZ78114.1.
JSZY01000046 Genomic DNA. Translation: KHA03417.1.
JTAE01000053 Genomic DNA. Translation: KHA25743.1.
JTAD01000031 Genomic DNA. Translation: KHA29173.1.
RefSeqiNP_845825.1. NC_003997.3.
WP_000473536.1. NZ_KN050651.1.
YP_020184.1. NC_007530.2.
YP_029548.1. NC_005945.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198094.BA_3551.

Protein family/group databases

CAZyiGH13. Glycoside Hydrolase Family 13.

Protocols and materials databases

DNASUi1084526.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP27311; AAP27311; BA_3551.
AAT32659; AAT32659; GBAA_3551.
AAT55599; AAT55599; BAS3291.
GeneIDi1084526.
2816336.
2849079.
KEGGiban:BA_3551.
bar:GBAA_3551.
bat:BAS3291.

Phylogenomic databases

HOGENOMiHOG000094847.
KOiK01176.
OMAiNDGNHWN.
OrthoDBiEOG65QWH3.

Enzyme and pathway databases

BioCyciANTHRA:AMYS-MONOMER.
BANT260799:GJAJ-3353-MONOMER.
BANT261594:GJ7F-3463-MONOMER.

Family and domain databases

Gene3Di2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR013776. A-amylase_thermo.
IPR015237. Alpha-amylase_C_pro.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR006589. Glyco_hydro_13_sub_cat_dom.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF09154. DUF1939. 1 hit.
[Graphical view]
PIRSFiPIRSF001021. Alph-amls_thrmst. 1 hit.
SMARTiSM00642. Aamy. 1 hit.
[Graphical view]
SUPFAMiSSF51445. SSF51445. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate PortonImported.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames ancestorImported and Ames AncestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.
  5. Tong Y.G., Huang Y., An X.P., Li S.S., Mi Z.Q., Pei G.Q., Zhang Z.Y., Fan H.
    Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HanImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A.Br.003Imported.
  7. "Draft Genome Sequence of Bacillus anthracis STI."
    Okinaka R.T., Challacombe J.F., Drees K., Birdsell D.N., Janke N., Naumann A., Seymour M., O'Neill H.H., Schupp J., Sahl J., Foster J.T., Pearson T., Keim P.
    Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: STI-1Imported.
  8. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BFVImported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Delta SterneImported.
  10. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031027Imported.
  11. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C.A., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031075Imported, 2000032879Imported, 2000032975Imported and 2000032979Imported.

Entry informationi

Entry nameiQ81YJ4_BACAN
AccessioniPrimary (citable) accession number: Q81YJ4
Secondary accession number(s): E9R8P4
, E9R8P5, Q6HVU0, Q6KQ03
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 4, 2015
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.