Q81X76 (TPIS_BACAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
May 1, 2013.
Version 80.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Triosephosphate isomerase Short name=TIM EC=5.3.1.1 Alternative name(s): Triose-phosphate isomerase | ||||||
| Gene names |
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| Organism | Bacillus anthracis [Reference proteome] [HAMAP] | ||||||
| Taxonomic identifier | 1392 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group![]() |
Protein attributes
| Sequence length | 251 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | D-glyceraldehyde 3-phosphate = glycerone phosphate. HAMAP-Rule MF_00147 |
| Pathway | Carbohydrate biosynthesis; gluconeogenesis. HAMAP-Rule MF_00147 Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1. HAMAP-Rule MF_00147 |
| Subunit structure | Homodimer By similarity. |
| Subcellular location | Cytoplasm By similarity. |
| Sequence similarities | Belongs to the triosephosphate isomerase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Gluconeogenesis Glycolysis Pentose shunt |
| Cellular component | Cytoplasm |
| Molecular function | Isomerase |
| PTM | Phosphoprotein |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological_process | gluconeogenesis Inferred from electronic annotation. Source: HAMAP glycolysisInferred from electronic annotation. Source: HAMAP pentose-phosphate shuntInferred from electronic annotation. Source: HAMAP |
| Cellular_component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular_function | triose-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 251 | 251 | Triosephosphate isomerase HAMAP-Rule MF_00147 | PRO_0000090174 | |||||
Sites | |||||||||
| Active site | 95 | 1 | Electrophile By similarity | ||||||
| Active site | 167 | 1 | Proton acceptor By similarity | ||||||
| Binding site | 9 | 1 | Substrate By similarity | ||||||
| Binding site | 11 | 1 | Substrate By similarity | ||||||
Amino acid modifications | |||||||||
| Modified residue | 213 | 1 | Phosphoserine By similarity | ||||||
Sequences
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References
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE016879 Genomic DNA. Translation: AAP29026.1. AE017334 Genomic DNA. Translation: AAT34500.2. AE017225 Genomic DNA. Translation: AAT57276.1. |
| RefSeq | NP_847540.1. NC_003997.3. YP_022025.2. NC_007530.2. YP_031226.1. NC_005945.1. |
3D structure databases | |
| ProteinModelPortal | Q81X76. |
| SMR | Q81X76. Positions 2-249. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | 198094.BA_5366. |
Protocols and materials databases | |
| DNASU | 1084904. |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | AAP29026; AAP29026; BA_5366. AAT34500; AAT34500; GBAA_5366. AAT57276; AAT57276; BAS4987. |
| GeneID | 1084904. 2818888. 2851859. |
| KEGG | ban:BA_5366. bar:GBAA_5366. bat:BAS4987. |
Phylogenomic databases | |
| eggNOG | COG0149. |
| HOGENOM | HOG000226412. |
| KO | K01803. |
| OMA | ISGQWPR. |
| ProtClustDB | PRK00042. |
Enzyme and pathway databases | |
| BioCyc | BANT260799:GJAJ-5061-MONOMER. BANT261594:GJ7F-5237-MONOMER. |
| UniPathway | UPA00109; UER00189. UPA00138. |
Family and domain databases | |
| Gene3D | 3.20.20.70. 1 hit. |
| HAMAP | MF_00147_B. TIM_B. |
| InterPro | IPR013785. Aldolase_TIM. IPR022896. TrioseP_Isoase_bac/euk. IPR000652. Triosephosphate_isomerase. IPR020861. Triosephosphate_isomerase_AS. [Graphical view] |
| PANTHER | PTHR21139. PTHR21139. 1 hit. |
| Pfam | PF00121. TIM. 1 hit. [Graphical view] |
| SUPFAM | SSF51351. Triophos_ismrse. 1 hit. |
| TIGRFAMs | TIGR00419. tim. 1 hit. |
| PROSITE | PS00171. TIM_1. 1 hit. PS51440. TIM_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | TPIS_BACAN | ||||||||
| Accession | Primary (citable) accession number: Q81X76 Secondary accession number(s): Q6HR12, Q6KKD1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with
