Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Tyrosine recombinase XerC

Gene

xerC

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids (By similarity).SAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei148 – 1481UniRule annotation
Active sitei172 – 1721UniRule annotation
Active sitei245 – 2451UniRule annotation
Active sitei248 – 2481UniRule annotation
Active sitei271 – 2711UniRule annotation
Active sitei280 – 2801O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotationSAAS annotation, Chromosome partitionUniRule annotationSAAS annotation, DNA integrationUniRule annotationSAAS annotation, DNA recombinationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3740-MONOMER.
BANT261594:GJ7F-3857-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine recombinase XerCUniRule annotation
Gene namesi
Name:xerCUniRule annotationImported
Ordered Locus Names:GBAA_3969Imported
ORF Names:TM00_19280Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000594 Componenti: Chromosome UP000031917 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi198094.BA_3969.

Structurei

3D structure databases

ProteinModelPortaliQ81WK4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000045294.
KOiK03733.
OMAiRVSECCH.
OrthoDBiEOG6PZXFP.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011931. Recomb_XerC.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF56349. SSF56349. 1 hit.
TIGRFAMsiTIGR02224. recomb_XerC. 1 hit.
TIGR02225. recomb_XerD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81WK4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNVKKLLQLF VGYLQIERNY SKYTIASYQN DLEHFVQFME REGISSFLDI
60 70 80 90 100
TYADVRLYLT TLHDEKLARK SVARKVSSLR SLYRFLMREG YRKDNPFALA
110 120 130 140 150
SLPKKELSIP KFLYAEELEE LFEVSDTETP LGQRNQALLE LMYATGIRVS
160 170 180 190 200
ECVNLQLTDI DFAVGTILVM GKGKKQRYIP FGSYAQDALI TYIENGRKQL
210 220 230 240 250
AEKTEEQSHM VFLNAKGTPL TSRGVRYVLN ELIKKASLTM RISPHILRHT
260 270 280 290
FATHMLDEGA DLRTVQELLG HENLSTTQIY THVSKERLRS VYMKHHPRA
Length:299
Mass (Da):34,593
Last modified:June 1, 2003 - v1
Checksum:iCDCD132A824335FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA. Translation: AAT33083.1.
CP010813 Genomic DNA. Translation: AJG30479.1.
RefSeqiNP_846212.1. NC_003997.3.
WP_001101226.1. NZ_KN050651.1.
YP_020608.1. NC_007530.2.
YP_029933.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP27698; AAP27698; BA_3969.
AAT33083; AAT33083; GBAA_3969.
AAT55984; AAT55984; BAS3682.
AIF57964; AIF57964; HYU01_19395.
AIK09984; AIK09984; DH23_3859.
AIK50587; AIK50587; DJ45_2038.
AIK55631; AIK55631; DJ44_2095.
AIM07678; AIM07678; BACvac02_4083.
AIM13152; AIM13152; BAHan_4187.
AJA87988; AJA87988; RT54_19120.
KFJ82638; KFJ82638; DJ42_3941.
KFL67863; KFL67863; DJ49_1132.
KGZ44723; KGZ44723; OY22_20860.
KGZ50126; KGZ50126; OY21_12560.
KGZ55630; KGZ55630; NX97_09235.
KGZ62050; KGZ62050; OY23_19500.
KGZ63565; KGZ63565; OY25_16710.
KGZ70428; KGZ70428; OY24_10225.
KGZ77734; KGZ77734; OY27_24500.
KGZ81695; KGZ81695; OY28_24645.
KGZ99271; KGZ99271; OY29_10570.
KHA01098; KHA01098; OY30_08205.
KHA03033; KHA03033; OY32_13415.
KHA07527; KHA07527; OY34_28080.
KHA08690; KHA08690; OY35_28110.
KHA25360; KHA25360; OY38_19095.
KHA26255; KHA26255; OY36_08560.
KHA28788; KHA28788; OY37_10440.
KHA35153; KHA35153; OY39_21130.
KHG46310; KHG46310; OY33_23280.
KHG53128; KHG53128; OY31_09930.
KHG59373; KHG59373; OY20_24090.
GeneIDi1086787.
2850972.
KEGGiban:BA_3969.
bar:GBAA_3969.
bat:BAS3682.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA. Translation: AAT33083.1.
CP010813 Genomic DNA. Translation: AJG30479.1.
RefSeqiNP_846212.1. NC_003997.3.
WP_001101226.1. NZ_KN050651.1.
YP_020608.1. NC_007530.2.
YP_029933.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81WK4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198094.BA_3969.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP27698; AAP27698; BA_3969.
AAT33083; AAT33083; GBAA_3969.
AAT55984; AAT55984; BAS3682.
AIF57964; AIF57964; HYU01_19395.
AIK09984; AIK09984; DH23_3859.
AIK50587; AIK50587; DJ45_2038.
AIK55631; AIK55631; DJ44_2095.
AIM07678; AIM07678; BACvac02_4083.
AIM13152; AIM13152; BAHan_4187.
AJA87988; AJA87988; RT54_19120.
KFJ82638; KFJ82638; DJ42_3941.
KFL67863; KFL67863; DJ49_1132.
KGZ44723; KGZ44723; OY22_20860.
KGZ50126; KGZ50126; OY21_12560.
KGZ55630; KGZ55630; NX97_09235.
KGZ62050; KGZ62050; OY23_19500.
KGZ63565; KGZ63565; OY25_16710.
KGZ70428; KGZ70428; OY24_10225.
KGZ77734; KGZ77734; OY27_24500.
KGZ81695; KGZ81695; OY28_24645.
KGZ99271; KGZ99271; OY29_10570.
KHA01098; KHA01098; OY30_08205.
KHA03033; KHA03033; OY32_13415.
KHA07527; KHA07527; OY34_28080.
KHA08690; KHA08690; OY35_28110.
KHA25360; KHA25360; OY38_19095.
KHA26255; KHA26255; OY36_08560.
KHA28788; KHA28788; OY37_10440.
KHA35153; KHA35153; OY39_21130.
KHG46310; KHG46310; OY33_23280.
KHG53128; KHG53128; OY31_09930.
KHG59373; KHG59373; OY20_24090.
GeneIDi1086787.
2850972.
KEGGiban:BA_3969.
bar:GBAA_3969.
bat:BAS3682.

Phylogenomic databases

HOGENOMiHOG000045294.
KOiK03733.
OMAiRVSECCH.
OrthoDBiEOG6PZXFP.

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3740-MONOMER.
BANT261594:GJ7F-3857-MONOMER.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011931. Recomb_XerC.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF56349. SSF56349. 1 hit.
TIGRFAMsiTIGR02224. recomb_XerC. 1 hit.
TIGR02225. recomb_XerD. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestorImported.
  2. "Genome sequence of Bacillus anthracis Pollino isolated from a bovine anthrax-burial site in Italy."
    Fasanella A., Braun P., Grass G., Hanczaruk M., Aceti A., Serrecchia L., Marino L., Georgi E., Antwerpen M.H.
    Submitted (JAN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PollinoImported.

Entry informationi

Entry nameiQ81WK4_BACAN
AccessioniPrimary (citable) accession number: Q81WK4
Secondary accession number(s): E9QX54
, E9QX55, Q6HUQ5, Q6KNY6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: May 27, 2015
This is version 104 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.