Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q81WK4

- Q81WK4_BACAN

UniProt

Q81WK4 - Q81WK4_BACAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Tyrosine recombinase XerC

Gene

xerC

Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC-XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids.UniRule annotationSAAS annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei148 – 1481UniRule annotation
Active sitei172 – 1721UniRule annotation
Active sitei245 – 2451UniRule annotation
Active sitei248 – 2481UniRule annotation
Active sitei271 – 2711UniRule annotation
Active sitei280 – 2801O-(3'-phospho-DNA)-tyrosine intermediateUniRule annotation

GO - Molecular functioni

  1. DNA binding Source: UniProtKB-KW
  2. tyrosine-based site-specific recombinase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. cell cycle Source: UniProtKB-KW
  2. cell division Source: UniProtKB-KW
  3. chromosome segregation Source: UniProtKB-HAMAP
  4. transposition, DNA-mediated Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Biological processi

Cell cycle, Cell divisionUniRule annotationSAAS annotation, Chromosome partitionUniRule annotationSAAS annotation, DNA integrationUniRule annotationSAAS annotation, DNA recombinationUniRule annotationSAAS annotation

Keywords - Ligandi

DNA-bindingUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3740-MONOMER.
BANT261594:GJ7F-3857-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Tyrosine recombinase XerCUniRule annotation
Gene namesi
Name:xerCUniRule annotationImported
Synonyms:xerDImported
Ordered Locus Names:BA_3969Imported, BAS3682Imported, GBAA_3969Imported
ORF Names:BACvac02_4083Imported, BAHan_4187Imported, DH23_3859Imported, DJ42_3941Imported, DJ44_2095Imported, DJ45_2038Imported, DJ49_1132Imported, HYU01_19395Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

Subcellular locationi

Cytoplasm UniRule annotationSAAS annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

CytoplasmUniRule annotationSAAS annotation

Interactioni

Subunit structurei

Forms a cyclic heterotetrameric complex composed of two molecules of XerC and two molecules of XerD.UniRule annotationSAAS annotation

Protein-protein interaction databases

STRINGi198094.BA_3969.

Family & Domainsi

Sequence similaritiesi

Belongs to the 'phage' integrase family. XerC subfamily.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000045294.
KOiK03733.
OMAiRIVLMGL.
OrthoDBiEOG6PZXFP.

Family and domain databases

Gene3Di1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPiMF_01808. Recomb_XerC.
InterProiIPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011931. Recomb_XerC.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view]
PfamiPF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view]
SUPFAMiSSF56349. SSF56349. 1 hit.
TIGRFAMsiTIGR02224. recomb_XerC. 1 hit.
TIGR02225. recomb_XerD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81WK4-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNVKKLLQLF VGYLQIERNY SKYTIASYQN DLEHFVQFME REGISSFLDI
60 70 80 90 100
TYADVRLYLT TLHDEKLARK SVARKVSSLR SLYRFLMREG YRKDNPFALA
110 120 130 140 150
SLPKKELSIP KFLYAEELEE LFEVSDTETP LGQRNQALLE LMYATGIRVS
160 170 180 190 200
ECVNLQLTDI DFAVGTILVM GKGKKQRYIP FGSYAQDALI TYIENGRKQL
210 220 230 240 250
AEKTEEQSHM VFLNAKGTPL TSRGVRYVLN ELIKKASLTM RISPHILRHT
260 270 280 290
FATHMLDEGA DLRTVQELLG HENLSTTQIY THVSKERLRS VYMKHHPRA
Length:299
Mass (Da):34,593
Last modified:June 1, 2003 - v1
Checksum:iCDCD132A824335FF
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP27698.1.
AE017334 Genomic DNA. Translation: AAT33083.1.
AE017225 Genomic DNA. Translation: AAT55984.1.
CP008846 Genomic DNA. Translation: AIF57964.1.
CP007660 Genomic DNA. Translation: AIK09984.1.
CP008752 Genomic DNA. Translation: AIK50587.1.
CP007704 Genomic DNA. Translation: AIK55631.1.
CP008853 Genomic DNA. Translation: AIM07678.1.
CP008854 Genomic DNA. Translation: AIM13152.1.
JNOD01000012 Genomic DNA. Translation: KFJ82638.1.
JMPV01000008 Genomic DNA. Translation: KFL67863.1.
RefSeqiNP_846212.1. NC_003997.3.
WP_001101226.1. NZ_JHDR01000018.1.
YP_020608.1. NC_007530.2.
YP_029933.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP27698; AAP27698; BA_3969.
AAT33083; AAT33083; GBAA_3969.
AAT55984; AAT55984; BAS3682.
GeneIDi1086787.
2818793.
2850972.
KEGGiban:BA_3969.
bar:GBAA_3969.
bat:BAS3682.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP27698.1 .
AE017334 Genomic DNA. Translation: AAT33083.1 .
AE017225 Genomic DNA. Translation: AAT55984.1 .
CP008846 Genomic DNA. Translation: AIF57964.1 .
CP007660 Genomic DNA. Translation: AIK09984.1 .
CP008752 Genomic DNA. Translation: AIK50587.1 .
CP007704 Genomic DNA. Translation: AIK55631.1 .
CP008853 Genomic DNA. Translation: AIM07678.1 .
CP008854 Genomic DNA. Translation: AIM13152.1 .
JNOD01000012 Genomic DNA. Translation: KFJ82638.1 .
JMPV01000008 Genomic DNA. Translation: KFL67863.1 .
RefSeqi NP_846212.1. NC_003997.3.
WP_001101226.1. NZ_JHDR01000018.1.
YP_020608.1. NC_007530.2.
YP_029933.1. NC_005945.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198094.BA_3969.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP27698 ; AAP27698 ; BA_3969 .
AAT33083 ; AAT33083 ; GBAA_3969 .
AAT55984 ; AAT55984 ; BAS3682 .
GeneIDi 1086787.
2818793.
2850972.
KEGGi ban:BA_3969.
bar:GBAA_3969.
bat:BAS3682.

Phylogenomic databases

HOGENOMi HOG000045294.
KOi K03733.
OMAi RIVLMGL.
OrthoDBi EOG6PZXFP.

Enzyme and pathway databases

BioCyci BANT260799:GJAJ-3740-MONOMER.
BANT261594:GJ7F-3857-MONOMER.

Family and domain databases

Gene3Di 1.10.150.130. 1 hit.
1.10.443.10. 1 hit.
HAMAPi MF_01808. Recomb_XerC.
InterProi IPR011010. DNA_brk_join_enz.
IPR013762. Integrase-like_cat-core.
IPR002104. Integrase_catalytic.
IPR023109. Integrase_recombinase_N.
IPR004107. Integrase_SAM-like_N.
IPR011931. Recomb_XerC.
IPR011932. Recomb_XerD.
IPR023009. Tyrosine_recombinase_XerC/XerD.
[Graphical view ]
Pfami PF02899. Phage_int_SAM_1. 1 hit.
PF00589. Phage_integrase. 1 hit.
[Graphical view ]
SUPFAMi SSF56349. SSF56349. 1 hit.
TIGRFAMsi TIGR02224. recomb_XerC. 1 hit.
TIGR02225. recomb_XerD. 1 hit.
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate PortonImported.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.
  5. Tong Y.G., Huang Y., An X.P., Li S.S., Mi Z.Q., Pei G.Q., Zhang Z.Y., Fan H.
    Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Cvac02Imported and HanImported.
  6. "Complete Genome Sequence of Bacillus anthracis HYU01, Isolated from Soil Samples in the Korean Peninsula."
    Kim S.K., Chung W.H., Kim S.H., Jung K.H., Kim N., Chai Y.G.
    Genome Announc. 2:e00769-14(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HYU01Imported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A.Br.003Imported and Smith 1013Imported.
  8. "Draft Genome Sequence of Bacillus anthracis STI."
    Okinaka R.T., Challacombe J.F., Drees K., Birdsell D.N., Janke N., Naumann A., Seymour M., O'Neill H.H., Schupp J., Sahl J., Foster J.T., Pearson T., Keim P.
    Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: STI-1Imported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BFVImported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Delta SterneImported.

Entry informationi

Entry nameiQ81WK4_BACAN
AccessioniPrimary (citable) accession number: Q81WK4
Secondary accession number(s): E9QX54
, E9QX55, Q6HUQ5, Q6KNY6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: November 26, 2014
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3