Q81WK1 (Q81WK1_BACAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Succinyl-CoA ligase [ADP-forming] subunit alpha RuleBase RU000699
EC=6.2.1.5 RuleBase RU000699

Gene names

Name:	sucD EMBL AAP27701.1
Ordered Locus Names:	BA_3973 EMBL AAP27701.1, BAS3686 EMBL AAT55988.1, GBAA_3973 EMBL AAT33087.1

Organism

Bacillus anthracis [Reference proteome] [HAMAP]

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	300 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	ATP + succinate + CoA = ADP + phosphate + succinyl-CoA. RuleBase RU000699
Subunit structure	Heterotetramer of two alpha and two beta subunits By similarity. RuleBase RU000699
Sequence similarities	Belongs to the succinate/malate CoA ligase alpha subunit family. RuleBase RU000677

Ontologies

Keywords
Ligand	ATP-binding RuleBase RU000699 Nucleotide-binding
Molecular function	Ligase RuleBase RU000677 EMBL AAP27701.1
PTM	Phosphoprotein RuleBase RU000677
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Molecular_function	ATP binding Inferred from electronic annotation. Source: UniProtKB-KW ATP citrate synthase activity Inferred from electronic annotation. Source: InterPro cofactor binding Inferred from electronic annotation. Source: InterPro succinate-CoA ligase (ADP-forming) activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Sites
	Active site	247	1	Tele-phosphohistidine intermediate By similarity PIRSR PIRSR001553-1

Sequences

	Sequence		Length	Mass (Da)
	Q81WK1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 1A659A2A64C215FC	FASTA	300	31,212
	10 20 30 40 50 60 MSVLVNKDTK VIVQGITGSQ GLFHTKQMIE YGTKIVGGVT PGKGGTDIEG VPVFDTVEDA 70 80 90 100 110 120 VKATGANASV VYVPPAFAAD AIMEAVDAEI DLVVCITEGI PVLDMVNVKR YMAGKHTRLL 130 140 150 160 170 180 GPNCPGVITP DECKIGIMPG YIHKKGHVGI VSRSGTLTYE AVHQLTQEGI GQSTAVGIGG 190 200 210 220 230 240 DPVNGTDFID ALKAFNEDEE THAVIMIGEI GGTAEEEAAE WVKANMTKPV VGFIGGQTAP 250 260 270 280 290 300 AGKRMGHAGA IISGGKGTAA EKIKTMEACG IKVAETPAVM GETLISVLKE KGLFETCKNY

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames EMBL AAP27701.1 and Ames / isolate Porton.
[2]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne EMBL AAT55988.1.
[3]	"The complete genome sequence of Bacillus anthracis Ames "Ancestor"." Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A. J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor and Ames Ancestor EMBL AAT33087.1.
[4]	Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Ames EMBL AAP27701.1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016879 Genomic DNA. Translation: AAP27701.1. AE017334 Genomic DNA. Translation: AAT33087.1. AE017225 Genomic DNA. Translation: AAT55988.1.
RefSeq	NP_846215.1. NC_003997.3. YP_020612.1. NC_007530.2. YP_029937.1. NC_005945.1.
3D structure databases
HSSP	HSSP built from PDB template 1SCU based on UniProtKB P07459.
SMR	Q81WK1. Positions 2-289.
ModBase	Search...
Protein-protein interaction databases
STRING	198094.BA_3973.
Protocols and materials databases
DNASU	1086597.
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	AAP27701; AAP27701; BA_3973. AAT33087; AAT33087; GBAA_3973. AAT55988; AAT55988; BAS3686.
GeneID	1086597. 2818535. 2849914.
KEGG	ban:BA_3973. bar:GBAA_3973. bat:BAS3686.
Phylogenomic databases
HOGENOM	HOG000239685.
KO	K01902.
OMA	KGRKKPM.
ProtClustDB	PRK05678.
Enzyme and pathway databases
BioCyc	BANT260799:GJAJ-3744-MONOMER. BANT261594:GJ7F-3861-MONOMER.
Family and domain databases
Gene3D	3.40.50.261. 1 hit. 3.40.50.720. 1 hit.
InterPro	IPR017440. Cit_synth/succinyl-CoA_lig_AS. IPR003781. CoA-bd. IPR005810. CoA_lig_alpha. IPR005811. CoA_ligase. IPR016040. NAD(P)-bd_dom. IPR016102. Succinyl-CoA_synth-like. [Graphical view]
Pfam	PF02629. CoA_binding. 1 hit. PF00549. Ligase_CoA. 1 hit. [Graphical view]
PIRSF	PIRSF001553. SucCS_alpha. 1 hit.
PRINTS	PR01798. SCOASYNTHASE.
SMART	SM00881. CoA_binding. 1 hit. [Graphical view]
SUPFAM	SSF52210. CoA_ligase. 1 hit.
TIGRFAMs	TIGR01019. sucCoAalpha. 1 hit.
PROSITE	PS01216. SUCCINYL_COA_LIG_1. 1 hit. PS00399. SUCCINYL_COA_LIG_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

Q81WK1_BACAN

Accession

Primary (citable) accession number: Q81WK1
Secondary accession number(s): E9R2H2 , E9R2H3, Q6HUQ1, Q6KNY3

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 91 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)