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Protein

Guanylate kinase

Gene

gmk

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Essential for recycling GMP and indirectly, cGMP.UniRule annotation

Catalytic activityi

ATP + GMP = ADP + GDP.UniRule annotation

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi13 – 20ATPUniRule annotation8

GO - Molecular functioni

Keywordsi

Molecular functionKinase, Transferase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Guanylate kinaseUniRule annotation (EC:2.7.4.8UniRule annotation)
Alternative name(s):
GMP kinaseUniRule annotation
Gene namesi
Name:gmkUniRule annotation
Ordered Locus Names:BA_4009, GBAA_4009, BAS3722
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome
  • UP000000427 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001704901 – 205Guanylate kinaseAdd BLAST205

Interactioni

Protein-protein interaction databases

STRINGi260799.BAS3722

Structurei

3D structure databases

ProteinModelPortaliQ81WG7
SMRiQ81WG7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini6 – 185Guanylate kinase-likeUniRule annotationAdd BLAST180

Sequence similaritiesi

Belongs to the guanylate kinase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0194 LUCA
HOGENOMiHOG000037639
KOiK00942
OMAiAGNYYGT

Family and domain databases

HAMAPiMF_00328 Guanylate_kinase, 1 hit
InterProiView protein in InterPro
IPR008145 GK/Ca_channel_bsu
IPR008144 Guanylate_kin-like_dom
IPR017665 Guanylate_kinase
IPR020590 Guanylate_kinase_CS
IPR027417 P-loop_NTPase
PfamiView protein in Pfam
PF00625 Guanylate_kin, 1 hit
SMARTiView protein in SMART
SM00072 GuKc, 1 hit
SUPFAMiSSF52540 SSF52540, 1 hit
TIGRFAMsiTIGR03263 guanyl_kin, 1 hit
PROSITEiView protein in PROSITE
PS00856 GUANYLATE_KINASE_1, 1 hit
PS50052 GUANYLATE_KINASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q81WG7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MRSRRGLLIV LSGPSGVGKG TVRKELFSHE DTRFQYSISV TTRKPREGEV
60 70 80 90 100
DGVDYFFKER EEFEEMIRNE KLLEWAEFVG NYYGTPIDYV EKTLQEGKDV
110 120 130 140 150
FLEIEVQGAI QVKKAFPEGV FIFLAPPSLS ELKNRIVGRG TETEDVIENR
160 170 180 190 200
LTVAKEEIDM MDAYDYVVEN DQVELACERI KAIVVGEHCR RERVAKYYKE

MTEGL
Length:205
Mass (Da):23,677
Last modified:June 1, 2003 - v1
Checksum:iBF987D07E1D8E531
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA Translation: AAP27737.1
AE017334 Genomic DNA Translation: AAT33126.1
AE017225 Genomic DNA Translation: AAT56024.1
RefSeqiNP_846251.1, NC_003997.3
WP_001257738.1, NZ_NVMW01000015.1
YP_029973.1, NC_005945.1

Genome annotation databases

EnsemblBacteriaiAAP27737; AAP27737; BA_4009
AAT33126; AAT33126; GBAA_4009
AAT56024; AAT56024; BAS3722
GeneIDi1087515
2848043
KEGGiban:BA_4009
bar:GBAA_4009
bat:BAS3722
PATRICifig|198094.11.peg.3979

Similar proteinsi

Entry informationi

Entry nameiKGUA_BACAN
AccessioniPrimary (citable) accession number: Q81WG7
Secondary accession number(s): Q6HUL5, Q6KNU9
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 98 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health