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Protein
Submitted name:

N-acetylmuramoyl-L-alanine amidase

Gene

cwlA

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi29 – 291Zinc; via pros nitrogenCombined sources
Metal bindingi129 – 1291Zinc; via pros nitrogenCombined sources
Metal bindingi137 – 1371ZincCombined sources

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Ligandi

Metal-bindingCombined sources, ZincCombined sources

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3842-MONOMER.
BANT261594:GJ7F-3960-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
N-acetylmuramoyl-L-alanine amidaseImported
Submitted name:
N-acetylmuramoyl-L-alanine amidase CwlAImported
Submitted name:
N-acetylmuramoyl-L-alanine amidase family proteinImported
Submitted name:
Prophage LambdaBa02, N-acetylmuramoyl-L-alanine amidase, family 2Imported
Gene namesi
Name:cwlAImported
Ordered Locus Names:GBAA_4073Imported
ORF Names:AB163_23095Imported, AB164_18615Imported, AB165_13530Imported, AB166_05495Imported, AB167_23390Imported, AB168_26695Imported, AB169_03440Imported, AB171_08255Imported, ADT20_07265Imported, ADT21_16400Imported, BASH2_01866Imported, BF27_3619Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_4073.

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YB0X-ray1.86A/B/C1-159[»]
2AR3X-ray2.20A/B/C1-160[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini13 – 154142Ami_2InterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4105T4X. Bacteria.
COG5632. LUCA.
HOGENOMiHOG000273688.
KOiK01447.
OMAiDENGWHA.
OrthoDBiEOG6W19KX.

Family and domain databases

Gene3Di3.40.80.10. 1 hit.
InterProiIPR021976. Amidase02_C.
IPR002502. Amidase_domain.
[Graphical view]
PfamiPF12123. Amidase02_C. 1 hit.
PF01510. Amidase_2. 1 hit.
[Graphical view]
SMARTiSM00644. Ami_2. 1 hit.
[Graphical view]
SUPFAMiSSF55846. SSF55846. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81WA9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEIRKKLVVP SKYGTKCPYT MKPKYITVHN TYNDAPAENE VNYMITNNNE
60 70 80 90 100
VSFHVAVDDK QAIQGIPWER NAWACGDGNG PGNRESISVE ICYSKSGGDR
110 120 130 140 150
YYKAENNAVD VVRQLMSMYN IPIENVRTHQ SWSGKYCPHR MLAEGRWGAF
160 170 180 190 200
IQKVKSGNVA SATVTPKQNI IQTGAFSPYE LPDAVGALKS LNMTGKAIIN
210 220 230
PEGLTYIVTD PTSDVQLQAF KEYLERKDWW YDDK
Length:234
Mass (Da):26,414
Last modified:June 1, 2003 - v1
Checksum:i07B0C56382F92D4B
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA. Translation: AAT33191.1.
CP009902 Genomic DNA. Translation: AJH88538.1.
AP014833 Genomic DNA. Translation: BAR75273.1.
LFYJ01000068 Genomic DNA. Translation: KOM59099.1.
LFYH01000003 Genomic DNA. Translation: KOM68880.1.
LFYG01000012 Genomic DNA. Translation: KOM72793.1.
LFYI01000025 Genomic DNA. Translation: KOM76622.1.
LFYF01000022 Genomic DNA. Translation: KOM83032.1.
LGIE01000010 Genomic DNA. Translation: KOM93964.1.
LGIG01000014 Genomic DNA. Translation: KON18119.1.
LGID01000085 Genomic DNA. Translation: KON22263.1.
LHUN01000026 Genomic DNA. Translation: KOR59117.1.
LHUO01000006 Genomic DNA. Translation: KOR68788.1.
RefSeqiWP_000405801.1. NZ_LHUO01000006.1.

Genome annotation databases

EnsemblBacteriaiAAT33191; AAT33191; GBAA_4073.
AJH88538; AJH88538; BF27_3619.
KOM59099; KOM59099; AB168_26695.
KOM68880; KOM68880; AB166_05495.
KOM72793; KOM72793; AB165_13530.
KOM76622; KOM76622; AB167_23390.
KOM83032; KOM83032; AB164_18615.
KOM93964; KOM93964; AB169_03440.
KON18119; KON18119; AB171_08255.
KON22263; KON22263; AB163_23095.
KOR59117; KOR59117; ADT21_16400.
KOR68788; KOR68788; ADT20_07265.
KEGGibanh:HYU01_19915.
bar:GBAA_4073.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA. Translation: AAT33191.1.
CP009902 Genomic DNA. Translation: AJH88538.1.
AP014833 Genomic DNA. Translation: BAR75273.1.
LFYJ01000068 Genomic DNA. Translation: KOM59099.1.
LFYH01000003 Genomic DNA. Translation: KOM68880.1.
LFYG01000012 Genomic DNA. Translation: KOM72793.1.
LFYI01000025 Genomic DNA. Translation: KOM76622.1.
LFYF01000022 Genomic DNA. Translation: KOM83032.1.
LGIE01000010 Genomic DNA. Translation: KOM93964.1.
LGIG01000014 Genomic DNA. Translation: KON18119.1.
LGID01000085 Genomic DNA. Translation: KON22263.1.
LHUN01000026 Genomic DNA. Translation: KOR59117.1.
LHUO01000006 Genomic DNA. Translation: KOR68788.1.
RefSeqiWP_000405801.1. NZ_LHUO01000006.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
1YB0X-ray1.86A/B/C1-159[»]
2AR3X-ray2.20A/B/C1-160[»]
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198094.BA_4073.

Protocols and materials databases

DNASUi1087444.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT33191; AAT33191; GBAA_4073.
AJH88538; AJH88538; BF27_3619.
KOM59099; KOM59099; AB168_26695.
KOM68880; KOM68880; AB166_05495.
KOM72793; KOM72793; AB165_13530.
KOM76622; KOM76622; AB167_23390.
KOM83032; KOM83032; AB164_18615.
KOM93964; KOM93964; AB169_03440.
KON18119; KON18119; AB171_08255.
KON22263; KON22263; AB163_23095.
KOR59117; KOR59117; ADT21_16400.
KOR68788; KOR68788; ADT20_07265.
KEGGibanh:HYU01_19915.
bar:GBAA_4073.

Phylogenomic databases

eggNOGiENOG4105T4X. Bacteria.
COG5632. LUCA.
HOGENOMiHOG000273688.
KOiK01447.
OMAiDENGWHA.
OrthoDBiEOG6W19KX.

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3842-MONOMER.
BANT261594:GJ7F-3960-MONOMER.

Family and domain databases

Gene3Di3.40.80.10. 1 hit.
InterProiIPR021976. Amidase02_C.
IPR002502. Amidase_domain.
[Graphical view]
PfamiPF12123. Amidase02_C. 1 hit.
PF01510. Amidase_2. 1 hit.
[Graphical view]
SMARTiSM00644. Ami_2. 1 hit.
[Graphical view]
SUPFAMiSSF55846. SSF55846. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "Structure and lytic activity of a Bacillus anthracis prophage endolysin."
    Low L.Y., Yang C., Perego M., Osterman A., Liddington R.C.
    J. Biol. Chem. 280:35433-35439(2005) [PubMed] [Europe PMC] [Abstract]
    Cited for: X-RAY CRYSTALLOGRAPHY (1.86 ANGSTROMS) OF 1-159 IN COMPLEX WITH ZINC.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestorImported.
  3. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2002013094Imported.
  4. "Bacillus anthracis whole genome sequence."
    Okutani A., Morikawa S., Inoue S.
    Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Shikan-NIIDImported.
  5. "Draft genome sequence of Bacillus anthracis strain K0021."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K0021Imported.
  6. "Draft genome sequence of Bacillus anthracis strain K1285."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K1285Imported.
  7. "Draft genome sequence of Bacillus anthracis strain K2129."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K2129Imported.
  8. "Draft genome sequence of Bacillus anthracis strain K2883."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K2883Imported.
  9. "Draft genome sequence of Bacillus anthracis strain K3974."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K3974Imported.
  10. "Draft genome sequence of Bacillus anthracis strain K4834."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K4834Imported.
  11. "Draft genome sequence of Bacillus anthracis strain K8215."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K8215Imported.
  12. "Draft genome sequence of Bacillus anthracis strain PAK-1."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PAK-1Imported.
  13. "Draft genome sequence of Bacillus anthracis strain A0021."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A0021Imported.
  14. "Draft genome sequence of Bacillus anthracis strain A0389."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A0389Imported.

Entry informationi

Entry nameiQ81WA9_BACAN
AccessioniPrimary (citable) accession number: Q81WA9
Secondary accession number(s): E9R7R5
, E9R7R6, Q6HUF3, Q6KNP0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 8, 2016
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.