Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

Bifunctional protein tilS/hprT

Gene

hprT

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

GlycosyltransferaseImported, Transferase

Names & Taxonomyi

Protein namesi
Submitted name:
Bifunctional protein tilS/hprTImported
Submitted name:
Hypoxanthine phosphoribosyltransferaseImported (EC:2.4.2.8Imported)
Submitted name:
Hypoxanthine-guanine phosphoribosyltransferaseImported
Gene namesi
Name:hprTImported
Synonyms:hptImported, hpt-1Imported, tilSImported
ORF Names:AB163_27565Imported, AB164_00620Imported, AB165_20870Imported, AB166_00070Imported, AB167_09190Imported, AB168_23940Imported, AB169_26755Imported, AB170_15985Imported, AB171_27575Imported, ABW01_27435Imported, ADT20_20990Imported, ADT21_10905Imported, BACvac02_0078Imported, BAHan_0077Imported, BASH2_00187Imported, BF27_1943Imported, HYU01_00365Imported, NX97_11215Imported, OY20_00895Imported, OY21_01355Imported, OY22_07855Imported, OY23_01275Imported, OY24_01950Imported, OY25_02380Imported, OY26_00855Imported, OY27_01325Imported, OY28_00785Imported, OY29_03285Imported, OY30_00195Imported, OY31_03025Imported, OY32_05190Imported, OY33_02045Imported, OY34_08245Imported, OY35_07930Imported, OY36_06080Imported, OY37_28710Imported, OY38_07840Imported, OY39_13570Imported, OY40_00215Imported, RT54_00365Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000035904 Componenti: Unassembled WGS sequence

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Structurei

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3H83X-ray2.06A/B/C/D1-180[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini15 – 160146PribosyltranInterPro annotationAdd
BLAST

Phylogenomic databases

eggNOGiENOG4108UGV. Bacteria.
COG0634. LUCA.
KOiK00760.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
InterProiIPR005904. Hxn_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01203. HGPRTase. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81VX6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MMNQDIEKVL ISEEQIQEKV LELGAIIAED YKNTVPLAIG VLKGAMPFMA
60 70 80 90 100
DLLKRTDTYL EMDFMAVSSY GHSTVSTGEV KILKDLDTSV EGRDILIVED
110 120 130 140 150
IIDSGLTLSY LVDLFKYRKA KSVKIVTLLD KPTGRKVDLK ADYVGFTVPH
160 170 180
EFVVGYGLDY KEQYRNLPYV GVLKPSVYSN
Length:180
Mass (Da):20,208
Last modified:June 1, 2003 - v1
Checksum:i5A34CE2B632D3566
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP008846 Genomic DNA. Translation: AIF54565.1.
CP008853 Genomic DNA. Translation: AIM04047.1.
CP008854 Genomic DNA. Translation: AIM09428.1.
CP010342 Genomic DNA. Translation: AJA84566.1.
CP009902 Genomic DNA. Translation: AJH86432.1.
AP014833 Genomic DNA. Translation: BAR73594.1.
JTAR01000027 Genomic DNA. Translation: KGZ52940.1.
JTAQ01000007 Genomic DNA. Translation: KGZ54143.1.
JTAS01000038 Genomic DNA. Translation: KGZ54575.1.
JSZR01000010 Genomic DNA. Translation: KGZ72366.1.
JSZP01000007 Genomic DNA. Translation: KGZ73502.1.
JSZQ01000008 Genomic DNA. Translation: KGZ74635.1.
JSZS01000003 Genomic DNA. Translation: KGZ89930.1.
JSZU01000003 Genomic DNA. Translation: KGZ90142.1.
JSZT01000004 Genomic DNA. Translation: KGZ90329.1.
JSZV01000012 Genomic DNA. Translation: KHA04778.1.
JSZY01000025 Genomic DNA. Translation: KHA05867.1.
JSZW01000001 Genomic DNA. Translation: KHA06667.1.
JTAB01000041 Genomic DNA. Translation: KHA15587.1.
JTAA01000017 Genomic DNA. Translation: KHA16196.1.
JTAD01000051 Genomic DNA. Translation: KHA20388.1.
JTAC01000018 Genomic DNA. Translation: KHA28011.1.
JTAE01000014 Genomic DNA. Translation: KHA34399.1.
JTAF01000030 Genomic DNA. Translation: KHA40355.1.
JTAG01000002 Genomic DNA. Translation: KHA45948.1.
JSZX01000019 Genomic DNA. Translation: KHG56163.1.
JSZZ01000010 Genomic DNA. Translation: KHG60324.1.
JTAP01000006 Genomic DNA. Translation: KHG64182.1.
LDPG01000031 Genomic DNA. Translation: KLV14471.1.
LFYJ01000064 Genomic DNA. Translation: KOM59727.1.
LFYH01000001 Genomic DNA. Translation: KOM69777.1.
LFYG01000019 Genomic DNA. Translation: KOM71386.1.
LFYI01000010 Genomic DNA. Translation: KOM79190.1.
LFYF01000006 Genomic DNA. Translation: KOM86363.1.
LGIE01000038 Genomic DNA. Translation: KOM90237.1.
LGIF01000020 Genomic DNA. Translation: KON04858.1.
LGIG01000035 Genomic DNA. Translation: KON15172.1.
LGID01000109 Genomic DNA. Translation: KON20796.1.
LHUN01000024 Genomic DNA. Translation: KOR60303.1.
LHUO01000018 Genomic DNA. Translation: KOR65960.1.
RefSeqiWP_000981838.1. NZ_LHUO01000018.1.

Genome annotation databases

EnsemblBacteriaiAIF54565; AIF54565; HYU01_00365.
AIM04047; AIM04047; BACvac02_0078.
AIM09428; AIM09428; BAHan_0077.
AJA84566; AJA84566; RT54_00365.
AJH86432; AJH86432; BF27_1943.
KGZ52940; KGZ52940; OY22_07855.
KGZ54143; KGZ54143; OY21_01355.
KGZ54575; KGZ54575; NX97_11215.
KGZ72366; KGZ72366; OY25_02380.
KGZ73502; KGZ73502; OY23_01275.
KGZ74635; KGZ74635; OY24_01950.
KGZ89930; KGZ89930; OY26_00855.
KGZ90142; KGZ90142; OY28_00785.
KGZ90329; KGZ90329; OY27_01325.
KHA04778; KHA04778; OY29_03285.
KHA05867; KHA05867; OY32_05190.
KHA06667; KHA06667; OY30_00195.
KHA15587; KHA15587; OY35_07930.
KHA16196; KHA16196; OY34_08245.
KHA20388; KHA20388; OY37_28710.
KHA28011; KHA28011; OY36_06080.
KHA34399; KHA34399; OY38_07840.
KHA40355; KHA40355; OY39_13570.
KHA45948; KHA45948; OY40_00215.
KHG56163; KHG56163; OY31_03025.
KHG60324; KHG60324; OY33_02045.
KHG64182; KHG64182; OY20_00895.
KLV14471; KLV14471; ABW01_27435.
KOM59727; KOM59727; AB168_23940.
KOM69777; KOM69777; AB166_00070.
KOM71386; KOM71386; AB165_20870.
KOM79190; KOM79190; AB167_09190.
KOM86363; KOM86363; AB164_00620.
KOM90237; KOM90237; AB169_26755.
KON04858; KON04858; AB170_15985.
KON15172; KON15172; AB171_27575.
KON20796; KON20796; AB163_27565.
KOR60303; KOR60303; ADT21_10905.
KOR65960; KOR65960; ADT20_20990.
KEGGibanh:HYU01_00365.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CP008846 Genomic DNA. Translation: AIF54565.1.
CP008853 Genomic DNA. Translation: AIM04047.1.
CP008854 Genomic DNA. Translation: AIM09428.1.
CP010342 Genomic DNA. Translation: AJA84566.1.
CP009902 Genomic DNA. Translation: AJH86432.1.
AP014833 Genomic DNA. Translation: BAR73594.1.
JTAR01000027 Genomic DNA. Translation: KGZ52940.1.
JTAQ01000007 Genomic DNA. Translation: KGZ54143.1.
JTAS01000038 Genomic DNA. Translation: KGZ54575.1.
JSZR01000010 Genomic DNA. Translation: KGZ72366.1.
JSZP01000007 Genomic DNA. Translation: KGZ73502.1.
JSZQ01000008 Genomic DNA. Translation: KGZ74635.1.
JSZS01000003 Genomic DNA. Translation: KGZ89930.1.
JSZU01000003 Genomic DNA. Translation: KGZ90142.1.
JSZT01000004 Genomic DNA. Translation: KGZ90329.1.
JSZV01000012 Genomic DNA. Translation: KHA04778.1.
JSZY01000025 Genomic DNA. Translation: KHA05867.1.
JSZW01000001 Genomic DNA. Translation: KHA06667.1.
JTAB01000041 Genomic DNA. Translation: KHA15587.1.
JTAA01000017 Genomic DNA. Translation: KHA16196.1.
JTAD01000051 Genomic DNA. Translation: KHA20388.1.
JTAC01000018 Genomic DNA. Translation: KHA28011.1.
JTAE01000014 Genomic DNA. Translation: KHA34399.1.
JTAF01000030 Genomic DNA. Translation: KHA40355.1.
JTAG01000002 Genomic DNA. Translation: KHA45948.1.
JSZX01000019 Genomic DNA. Translation: KHG56163.1.
JSZZ01000010 Genomic DNA. Translation: KHG60324.1.
JTAP01000006 Genomic DNA. Translation: KHG64182.1.
LDPG01000031 Genomic DNA. Translation: KLV14471.1.
LFYJ01000064 Genomic DNA. Translation: KOM59727.1.
LFYH01000001 Genomic DNA. Translation: KOM69777.1.
LFYG01000019 Genomic DNA. Translation: KOM71386.1.
LFYI01000010 Genomic DNA. Translation: KOM79190.1.
LFYF01000006 Genomic DNA. Translation: KOM86363.1.
LGIE01000038 Genomic DNA. Translation: KOM90237.1.
LGIF01000020 Genomic DNA. Translation: KON04858.1.
LGIG01000035 Genomic DNA. Translation: KON15172.1.
LGID01000109 Genomic DNA. Translation: KON20796.1.
LHUN01000024 Genomic DNA. Translation: KOR60303.1.
LHUO01000018 Genomic DNA. Translation: KOR65960.1.
RefSeqiWP_000981838.1. NZ_LHUO01000018.1.

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3H83X-ray2.06A/B/C/D1-180[»]
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAIF54565; AIF54565; HYU01_00365.
AIM04047; AIM04047; BACvac02_0078.
AIM09428; AIM09428; BAHan_0077.
AJA84566; AJA84566; RT54_00365.
AJH86432; AJH86432; BF27_1943.
KGZ52940; KGZ52940; OY22_07855.
KGZ54143; KGZ54143; OY21_01355.
KGZ54575; KGZ54575; NX97_11215.
KGZ72366; KGZ72366; OY25_02380.
KGZ73502; KGZ73502; OY23_01275.
KGZ74635; KGZ74635; OY24_01950.
KGZ89930; KGZ89930; OY26_00855.
KGZ90142; KGZ90142; OY28_00785.
KGZ90329; KGZ90329; OY27_01325.
KHA04778; KHA04778; OY29_03285.
KHA05867; KHA05867; OY32_05190.
KHA06667; KHA06667; OY30_00195.
KHA15587; KHA15587; OY35_07930.
KHA16196; KHA16196; OY34_08245.
KHA20388; KHA20388; OY37_28710.
KHA28011; KHA28011; OY36_06080.
KHA34399; KHA34399; OY38_07840.
KHA40355; KHA40355; OY39_13570.
KHA45948; KHA45948; OY40_00215.
KHG56163; KHG56163; OY31_03025.
KHG60324; KHG60324; OY33_02045.
KHG64182; KHG64182; OY20_00895.
KLV14471; KLV14471; ABW01_27435.
KOM59727; KOM59727; AB168_23940.
KOM69777; KOM69777; AB166_00070.
KOM71386; KOM71386; AB165_20870.
KOM79190; KOM79190; AB167_09190.
KOM86363; KOM86363; AB164_00620.
KOM90237; KOM90237; AB169_26755.
KON04858; KON04858; AB170_15985.
KON15172; KON15172; AB171_27575.
KON20796; KON20796; AB163_27565.
KOR60303; KOR60303; ADT21_10905.
KOR65960; KOR65960; ADT20_20990.
KEGGibanh:HYU01_00365.

Phylogenomic databases

eggNOGiENOG4108UGV. Bacteria.
COG0634. LUCA.
KOiK00760.

Family and domain databases

Gene3Di3.40.50.2020. 1 hit.
InterProiIPR005904. Hxn_phspho_trans.
IPR000836. PRibTrfase_dom.
IPR029057. PRTase-like.
[Graphical view]
PfamiPF00156. Pribosyltran. 1 hit.
[Graphical view]
SUPFAMiSSF53271. SSF53271. 1 hit.
TIGRFAMsiTIGR01203. HGPRTase. 1 hit.
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "2.06 Angstrom resolution structure of a hypoxanthine-guanine phosphoribosyltransferase (hpt-1) from Bacillus anthracis str. 'Ames Ancestor'."
    Center for Structural Genomics of Infectious Diseases (CSGID)
    Halavaty A.S., Shuvalova L., Minasov G., Dubrovska I., Peterson S.N., Anderson W.F.
    Submitted (APR-2009) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.06 ANGSTROMS).
  2. Jiao Y.-Y., Chen X., Wu J.
    Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Cvac02Imported and HanImported.
  3. "Complete Genome Sequence of Bacillus anthracis HYU01, Isolated from Soil Samples in the Korean Peninsula."
    Kim S.K., Chung W.H., Kim S.H., Jung K.H., Kim N., Chai Y.G.
    Genome Announc. 2:e00769-14(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HYU01Imported.
  4. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C.A., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031006Imported, 2000031008Imported, 2000031023Imported, 2000031027Imported, 2000031031Imported, 2000031038Imported, 2000031039Imported, 2000031052Imported, 2000031075Imported, 2000031709Imported, 2000031765Imported, 2000032819Imported, 2000032832Imported, 2000032879Imported, 2000032892Imported, 2000032951Imported, 2000032967Imported, 2000032968Imported, 2000032975Imported, 2000032979Imported, 2000032989Imported and 2002013094Imported.
  5. "Multiplex PCR for Species-Level Identification of Bacillus anthracis and Detection of pXO1, pXO2, and Related Plasmids."
    Hazbon M.H., Riojas M.A., Damon A.M., Alalade R.O., Cantwell B.J., Monaco A., King S., Sohrabi A.
    Submitted (DEC-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A0157Imported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2002013094Imported.
  7. "Bacillus anthracis whole genome sequence."
    Okutani A., Morikawa S., Inoue S.
    Submitted (MAR-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Shikan-NIIDImported.
  8. "Whole genome sequence and identification of bacterial endophytes from Costus igneus."
    Lee Y.P., Gan H.M., Eng W., Wheatley M.S., Caraballo A., Polter S., Savka M.A., Hudson A.O.
    Submitted (MAY-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: RIT375Imported.
  9. "Draft genome sequence of Bacillus anthracis strain K0021."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K0021Imported.
  10. "Draft genome sequence of Bacillus anthracis strain K1129."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K1129Imported.
  11. "Draft genome sequence of Bacillus anthracis strain K1285."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K1285Imported.
  12. "Draft genome sequence of Bacillus anthracis strain K2129."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K2129Imported.
  13. "Draft genome sequence of Bacillus anthracis strain K2883."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K2883Imported.
  14. "Draft genome sequence of Bacillus anthracis strain K3974."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K3974Imported.
  15. "Draft genome sequence of Bacillus anthracis strain K4834."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K4834Imported.
  16. "Draft genome sequence of Bacillus anthracis strain K8215."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: K8215Imported.
  17. "Draft genome sequence of Bacillus anthracis strain PAK-1."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUN-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: PAK-1Imported.
  18. "Draft genome sequence of Bacillus anthracis strain A0021."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A0021Imported.
  19. "Draft genome sequence of Bacillus anthracis strain A0389."
    Consortium for Microbial Forensics and Genomics (microFORGE)
    Knight B.M., O'Shea R.M., Jones B.A., Roberts D.P., Lin D., Hari K., Winegar R.A.
    Submitted (JUL-2015) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A0389Imported.

Entry informationi

Entry nameiQ81VX6_BACAN
AccessioniPrimary (citable) accession number: Q81VX6
Secondary accession number(s): E9R985, Q6I4Y0, Q6KYM4
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: June 8, 2016
This is version 118 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureCombined sources, Complete proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.