SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q81VN5

- GLMS_BACAN

UniProt

Q81VN5 - GLMS_BACAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]
Gene
glmS, BA_0159, GBAA_0159, BAS0160
Organism
Bacillus anthracis
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei595 – 5951For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciANTHRA:GLMS-MONOMER.
BANT260799:GJAJ-182-MONOMER.
BANT261594:GJ7F-184-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Ordered Locus Names:BA_0159, GBAA_0159, BAS0160
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 600599Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotation
PRO_0000135293Add
BLAST

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi198094.BA_0159.

Structurei

3D structure databases

ProteinModelPortaliQ81VN5.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 217216Glutamine amidotransferase type-2
Add
BLAST
Domaini283 – 422140SIS 1
Add
BLAST
Domaini452 – 590139SIS 2
Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
HOGENOMiHOG000258896.
KOiK00820.
OMAiSVFETQT.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q81VN5-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIVGFIGE QDAKEILLKG LEKLEYRGYD SAGIAVQAEN GVVVYKEKGR    50
IAKLREIVDE NVAASVGIGH TRWATHGVPS KVNAHPHQST SKRFTLVHNG 100
VIENYELVKK EYLQDVTFVS ETDTEVIVQL MEQQVSTGLS VEEAFRNTLS 150
LLHGSYAIGL LDAENPNMIY VAKNKSPLLV GVGDNFNVVA SDAMAMLQVT 200
DQFIELMDKE IVIVMKESIT IKNLQGETIE RAPFTAELDA SDIEKGTYPH 250
FMLKEIDEQP LVIRNIIQKY QDENGEIELD QDIRNAILDS DRIYIIACGT 300
SYHAGLVGKQ FIEKFAKMPV EVHVASEFSY NMPLLTERPF FIYISQSGET 350
ADSRAVLVQT NEMGHKALTI TNVPGSTLSR EADYTLPLYA GPEIAVASTK 400
AYTAQLAVLS ILAADIAKAK GEVLGFDLTH ELGLVANAMI ELCDQKEEMD 450
ALAKQFLATT RNCFFIGRSV DFYVGLEGAL KLKEISYIQA EGFAGGELKH 500
GTIALIENGT PVIALATQEH VNLGIRGNVK EVVARGANPC IISMKGLEME 550
GDSFVLPAVH EALAPLVAVI PLQLISYYAA LHRECDVDKP RNLAKSVTVE 600
Length:600
Mass (Da):65,765
Last modified:January 23, 2007 - v3
Checksum:iFF3FB8AF45C2F11F
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP24211.1.
AE017334 Genomic DNA. Translation: AAT29240.1.
AE017225 Genomic DNA. Translation: AAT52496.1.
RefSeqiNP_842725.1. NC_003997.3.
YP_016765.1. NC_007530.2.
YP_026445.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP24211; AAP24211; BA_0159.
AAT29240; AAT29240; GBAA_0159.
AAT52496; AAT52496; BAS0160.
GeneIDi1087656.
2819139.
2847978.
KEGGiban:BA_0159.
bar:GBAA_0159.
bat:BAS0160.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP24211.1 .
AE017334 Genomic DNA. Translation: AAT29240.1 .
AE017225 Genomic DNA. Translation: AAT52496.1 .
RefSeqi NP_842725.1. NC_003997.3.
YP_016765.1. NC_007530.2.
YP_026445.1. NC_005945.1.

3D structure databases

ProteinModelPortali Q81VN5.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198094.BA_0159.

Protocols and materials databases

DNASUi 1087656.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP24211 ; AAP24211 ; BA_0159 .
AAT29240 ; AAT29240 ; GBAA_0159 .
AAT52496 ; AAT52496 ; BAS0160 .
GeneIDi 1087656.
2819139.
2847978.
KEGGi ban:BA_0159.
bar:GBAA_0159.
bat:BAS0160.

Phylogenomic databases

eggNOGi COG0449.
HOGENOMi HOG000258896.
KOi K00820.
OMAi SVFETQT.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci ANTHRA:GLMS-MONOMER.
BANT260799:GJAJ-182-MONOMER.
BANT261594:GJ7F-184-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames / isolate Porton.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames ancestor.
  3. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sterne.

Entry informationi

Entry nameiGLMS_BACAN
AccessioniPrimary (citable) accession number: Q81VN5
Secondary accession number(s): Q6I4N5, Q6KYD4
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 84 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi