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Reviewed, UniProtKB/Swiss-Prot Q81V21 (UPPP3_BACAN)

Last modified January 19, 2010. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Undecaprenyl-diphosphatase 3
    EC=3.6.1.27
Alternative name(s):
    Undecaprenyl pyrophosphate phosphatase 3
    Bacitracin resistance protein 3
Gene names
Name: uppP3
Synonyms: bacA-3, bacA3, upk3
Ordered Locus Names: BA_0683, GBAA_0683, BAS0649
OrganismBacillus anthracis [Complete proteome] [HAMAP]
Taxonomic identifier1392 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

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Protein attributes

Sequence length270 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin By similarity. HAMAP MF_01006

Catalytic activity

Undecaprenyl diphosphate + H2O = undecaprenyl phosphate + phosphate. HAMAP MF_01006

Subcellular location

Cell membrane; Multi-pass membrane protein By similarity HAMAP MF_01006.

Miscellaneous

Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available. HAMAP MF_01006

Sequence similarities

Belongs to the uppP family.

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 270270Undecaprenyl-diphosphatase 3 HAMAP MF_01006
PRO_0000151087

Regions

Transmembrane5 – 2521 Potential
Transmembrane42 – 6221 Potential
Transmembrane89 – 10921 Potential
Transmembrane117 – 13721 Potential
Transmembrane192 – 21221 Potential
Transmembrane220 – 24021 Potential
Transmembrane250 – 27021 Potential

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Sequences

Sequence LengthMass (Da)Tools
Q81V21-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: B096AA4C6552F2EC

FASTA27030,004
        10         20         30         40         50         60 
MEQFYYILKY LILGLFQGLT EPIPISSSGH LVLAQHLLGL KIEGFSFELL VNSASLLAVL 

        70         80         90        100        110        120 
LIYRNDLIRL TKNGLSYIFT RAEDAKSDFF FIIYLVIATI PAGVIGVLFK DYIDQYLKGV 

       130        140        150        160        170        180 
KMVGISLLIT AVGLWIIRNL RGRRNDGDLS MKDAIIVGLA QACALIPGIS RSGATIVAAM 

       190        200        210        220        230        240 
LLGMKQETAL RFSFLLYIPV SLGGLLLSIT DIAKDPNLDT LFVPYIVAFI ATFIMTYISL 

       250        260        270 
KWFMNIMAKG NLKYFSFYCI IVGVLTLIFL

« Hide

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References

[1]"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. expand/collapse author list , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
Nature 423:81-86(2003) [PubMed: 12721629] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames / isolate Porton.
[2]"Bacillus anthracis comparative genomics."
Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M.
Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames ancestor.
[3]"Complete genome sequence of Bacillus anthracis Sterne."
Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sterne.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		AE016879 Genomic DNA. Translation: AAP24696.1.
AE017334 Genomic DNA. Translation: AAT29787.1.
AE017225 Genomic DNA. Translation: AAT52977.1.
RefSeqNP_843210.1.
YP_017312.1.
YP_026926.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID1088072.
2814973.
2848191.
GenomeReviewsGene locus BA_0683 in contig AE016879_GR.
Gene locus BAS0649 in contig AE017225_GR.
Gene locus GBAA_0683 in contig AE017334_GR.
KEGGban:BA0683.
bar:GBAA0683.
bat:BAS0649.
TIGRBA_0683.
GBAA_0683.

Phylogenomic databases

HOGENOMHBG391969.
OMAFALLWYF.

Enzyme and pathway databases

BioCycBANT260799:BAS0649-MONOMER.
BANT261594:GBAA0683-MONOMER.
BRENDA3.6.1.27. 267517.

Family and domain databases

HAMAPMF_01006. Undec_diphosphatase.
[Tree]
InterProIPR003824. Bacitracin-R_BacA.
[Graphical view]
PfamPF02673. BacA. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameUPPP3_BACAN
AccessionPrimary (citable) accession number: Q81V21
Secondary accession number(s): Q6I3A4, Q6KX21
Entry history
Integrated into UniProtKB/Swiss-Prot: April 13, 2004
Last sequence update: June 1, 2003
Last modified: January 19, 2010
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents