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Protein

Methylglyoxal synthase

Gene

mgsA

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the formation of methylglyoxal from dihydroxyacetone phosphate.UniRule annotation

Catalytic activityi

Glycerone phosphate = methylglyoxal + phosphate.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei8SubstrateUniRule annotation1
Binding sitei12SubstrateUniRule annotation1
Active sitei60Proton donor/acceptorUniRule annotation1
Binding sitei87SubstrateUniRule annotation1

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLyase

Names & Taxonomyi

Protein namesi
Recommended name:
Methylglyoxal synthaseUniRule annotation (EC:4.2.3.3UniRule annotation)
Short name:
MGSUniRule annotation
Gene namesi
Name:mgsAUniRule annotation
Ordered Locus Names:BA_1556, GBAA_1556, BAS1443
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome
  • UP000000427 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001786061 – 131Methylglyoxal synthaseAdd BLAST131

Interactioni

Protein-protein interaction databases

STRINGi260799.BAS1443

Structurei

3D structure databases

ProteinModelPortaliQ81ST9
SMRiQ81ST9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini1 – 131MGS-likeUniRule annotationAdd BLAST131

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni34 – 37Substrate bindingUniRule annotation4
Regioni54 – 55Substrate bindingUniRule annotation2

Sequence similaritiesi

Belongs to the methylglyoxal synthase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4108Z5K Bacteria
COG1803 LUCA
HOGENOMiHOG000283729
KOiK01734
OMAiRACDVHN

Family and domain databases

CDDicd01422 MGS, 1 hit
Gene3Di3.40.50.1380, 1 hit
HAMAPiMF_00549 Methylglyoxal_synth, 1 hit
InterProiView protein in InterPro
IPR004363 Methylgl_synth
IPR018148 Methylglyoxal_synth_AS
IPR011607 MGS-like_dom
IPR036914 MGS-like_dom_sf
PANTHERiPTHR30492 PTHR30492, 1 hit
PfamiView protein in Pfam
PF02142 MGS, 1 hit
PIRSFiPIRSF006614 Methylglyox_syn, 1 hit
SMARTiView protein in SMART
SM00851 MGS, 1 hit
SUPFAMiSSF52335 SSF52335, 1 hit
TIGRFAMsiTIGR00160 MGSA, 1 hit
PROSITEiView protein in PROSITE
PS01335 METHYLGLYOXAL_SYNTH, 1 hit
PS51855 MGS, 1 hit

Sequencei

Sequence statusi: Complete.

Q81ST9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKIALIAHDK KKEDMVSFAY AYKPIFEQHE LFATGTTGLR IMEATGLVVT
60 70 80 90 100
RYQSGPLGGD QEIGAMIAKN DLDMVIFFRD PLTAQPHEPD VNALLRLCDV
110 120 130
YAIPLATNMA SAEMLMHALE RGDLDYRKLR K
Length:131
Mass (Da):14,700
Last modified:June 1, 2003 - v1
Checksum:i4255982C163A1CED
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA Translation: AAP25492.1
AE017334 Genomic DNA Translation: AAT30653.1
AE017225 Genomic DNA Translation: AAT53763.1
RefSeqiNP_844006.1, NC_003997.3
WP_000684757.1, NZ_PPES01000002.1
YP_027712.1, NC_005945.1

Genome annotation databases

EnsemblBacteriaiAAP25492; AAP25492; BA_1556
AAT30653; AAT30653; GBAA_1556
AAT53763; AAT53763; BAS1443
GeneIDi1087213
2848233
KEGGiban:BA_1556
bar:GBAA_1556
bat:BAS1443
PATRICifig|198094.11.peg.1526

Similar proteinsi

Entry informationi

Entry nameiMGSA_BACAN
AccessioniPrimary (citable) accession number: Q81ST9
Secondary accession number(s): Q6I119, Q6KUX2
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 95 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

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