SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q81RG8

- Q81RG8_BACAN

UniProt

Q81RG8 - Q81RG8_BACAN

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Alanine racemase

Gene
dal2, BA_2079, BAS1932, GBAA_2079
Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 3 out of 5 - Experimental evidence at protein leveli

Functioni

Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids By similarity.UniRule annotation

Catalytic activityi

L-alanine = D-alanine.UniRule annotationSAAS annotations

Cofactori

Pyridoxal phosphate By similarity.UniRule annotationSAAS annotations

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei41 – 411Proton acceptor; specific for D-alanine By similarityUniRule annotation
Binding sitei139 – 1391Substrate By similarityUniRule annotation
Active sitei269 – 2691Proton acceptor; specific for L-alanine By similarityUniRule annotation
Binding sitei317 – 3171Substrate; via amide nitrogen By similarityUniRule annotation

GO - Molecular functioni

  1. alanine racemase activity Source: UniProtKB-HAMAP
  2. pyridoxal phosphate binding Source: UniProtKB-HAMAP

GO - Biological processi

  1. D-alanine biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

IsomeraseUniRule annotationSAAS annotationsImported

Keywords - Ligandi

Pyridoxal phosphateUniRule annotationSAAS annotations

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-2000-MONOMER.
BANT261594:GJ7F-2077-MONOMER.
UniPathwayiUPA00042; UER00497.

Names & Taxonomyi

Protein namesi
Recommended name:
Alanine racemaseUniRule annotation (EC:5.1.1.1UniRule annotation)
Gene namesi
Name:dal2Imported
Ordered Locus Names:BA_2079Imported, BAS1932Imported, GBAA_2079Imported
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000005639: Chromosome, UP000000594: Chromosome

PTM / Processingi

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei41 – 411N6-(pyridoxal phosphate)lysine By similarityUniRule annotation

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_2079.

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000031444.
KOiK01775.
OMAiRIGISIY.
OrthoDBiEOG6PP9NJ.

Family and domain databases

Gene3Di2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPiMF_01201. Ala_racemase.
InterProiIPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view]
PfamiPF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view]
PRINTSiPR00992. ALARACEMASE.
SMARTiSM01005. Ala_racemase_C. 1 hit.
[Graphical view]
SUPFAMiSSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsiTIGR00492. alr. 1 hit.
PROSITEiPS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81RG8-1 [UniParc]FASTAAdd to Basket

« Hide

MSLKYGRDTI VEVDLNAVKH NVKEFKKRVN DENIAMMAAV KANGYGHGAV    50
EVAKAAIEAG INQLAIAFVD EAIELREAGI NVPILILGYT SVAAAEEAIQ 100
YDVMMTVYRS EDLQGINEIA NRLQKKAQIQ VKIDTGMSRI GLQEEEVKPF 150
LEELKRMEYV EVVGMFTHYS TADEIDKSYT NMQTSLFEKA VNTAKELGIH 200
IPYIHSSNSA GSMEPSNTFQ NMVRVGIGIY GMYPSKEVNH SVVSLQPALS 250
LKSKVAHIKH AKKNRGVSYG NTYVTTGEEW IATVPIGYAD GYNRQLSNKG 300
HALINGVRVP VIGRVCMDQL MLDVSKAMPV QVGDEVVFYG KQGEENIAVE 350
EIADMLGTIN YEVTCMLDRR IPRVYKENNE TTAVVNILRK N 391
Length:391
Mass (Da):43,372
Last modified:June 1, 2003 - v1
Checksum:iF8AA173912483DF4
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP25965.1.
AE017334 Genomic DNA. Translation: AAT31196.1.
AE017225 Genomic DNA. Translation: AAT54246.1.
RefSeqiNP_844479.1. NC_003997.3.
YP_018721.1. NC_007530.2.
YP_028195.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP25965; AAP25965; BA_2079.
AAT31196; AAT31196; GBAA_2079.
AAT54246; AAT54246; BAS1932.
GeneIDi1087070.
2819479.
2848430.
KEGGiban:BA_2079.
bar:GBAA_2079.
bat:BAS1932.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP25965.1 .
AE017334 Genomic DNA. Translation: AAT31196.1 .
AE017225 Genomic DNA. Translation: AAT54246.1 .
RefSeqi NP_844479.1. NC_003997.3.
YP_018721.1. NC_007530.2.
YP_028195.1. NC_005945.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198094.BA_2079.

Protocols and materials databases

DNASUi 1087070.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP25965 ; AAP25965 ; BA_2079 .
AAT31196 ; AAT31196 ; GBAA_2079 .
AAT54246 ; AAT54246 ; BAS1932 .
GeneIDi 1087070.
2819479.
2848430.
KEGGi ban:BA_2079.
bar:GBAA_2079.
bat:BAS1932.

Phylogenomic databases

HOGENOMi HOG000031444.
KOi K01775.
OMAi RIGISIY.
OrthoDBi EOG6PP9NJ.

Enzyme and pathway databases

UniPathwayi UPA00042 ; UER00497 .
BioCyci BANT260799:GJAJ-2000-MONOMER.
BANT261594:GJ7F-2077-MONOMER.

Family and domain databases

Gene3Di 2.40.37.10. 1 hit.
3.20.20.10. 1 hit.
HAMAPi MF_01201. Ala_racemase.
InterProi IPR000821. Ala_racemase.
IPR009006. Ala_racemase/Decarboxylase_C.
IPR011079. Ala_racemase_C.
IPR001608. Ala_racemase_N.
IPR020622. Ala_racemase_pyridoxalP-BS.
IPR029066. PLP-binding_barrel.
[Graphical view ]
Pfami PF00842. Ala_racemase_C. 1 hit.
PF01168. Ala_racemase_N. 1 hit.
[Graphical view ]
PRINTSi PR00992. ALARACEMASE.
SMARTi SM01005. Ala_racemase_C. 1 hit.
[Graphical view ]
SUPFAMi SSF50621. SSF50621. 1 hit.
SSF51419. SSF51419. 1 hit.
TIGRFAMsi TIGR00492. alr. 1 hit.
PROSITEi PS00395. ALANINE_RACEMASE. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolsto A.B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate Porton.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames ancestor and Ames AncestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.

Entry informationi

Entry nameiQ81RG8_BACAN
AccessioniPrimary (citable) accession number: Q81RG8
Secondary accession number(s): E9R1M1
, E9R1M2, Q6HZP3, Q6KTN0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 108 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

External Data

Dasty 3

Similar proteinsi