Q81QR8 (Q81QR8_BACAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Carboxyvinyl-carboxyphosphonate phosphorylmutase EMBL AAT54502.1

Submitted name:
Methylisocitrate lyase EMBL AAP26219.1
EC=4.1.3.30 EMBL AAP26219.1

Gene names

Name:	prpB EMBL AAP26219.1
Ordered Locus Names:	BA_2350 EMBL AAP26219.1, BAS2190 EMBL AAT54502.1, GBAA_2350 EMBL AAT31469.1

Organism

Bacillus anthracis [Reference proteome] [HAMAP]

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	302 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Lyase EMBL AAP26219.1
Technical term	3D-structure PDB 4IQE PDB 4IQD Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	propionate catabolic process, 2-methylcitrate cycle Inferred from electronic annotation. Source: InterPro
Molecular_function	methylisocitrate lyase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q81QR8 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: FFCD10E8A9CB1F7B	FASTA	302	33,016
	10 20 30 40 50 60 MAWVVNKQST QEELANRFRA LVEANEILQI PGAHDAMAAL VARNTGFLAL YLSGAAYTAS 70 80 90 100 110 120 KGLPDLGIVT STEVAERARD LVRATDLPVL VDIDTGFGGV LNVARTAVEM VEAKVAAVQI 130 140 150 160 170 180 EDQQLPKKCG HLNGKKLVTT EELVQKIKAI KEVAPSLYIV ARTDARGVEG LDEAIERANA 190 200 210 220 230 240 YVKAGADAIF PEALQSEEEF RLFNSKVNAP LLANMTEFGK TPYYSAEEFA NMGFQMVIYP 250 260 270 280 290 300 VTSLRVAAKA YENVFTLIKE TGSQKDALSN MQTRSELYET ISYHDFEELD TGIAKTVLSE DQ

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames EMBL AAP26219.1 and Ames / isolate Porton.
[2]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne EMBL AAT54502.1.
[3]	"The complete genome sequence of Bacillus anthracis Ames "Ancestor"." Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A. J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor and Ames Ancestor EMBL AAT31469.1.
[4]	Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Ames EMBL AAP26219.1.
[5]	"Crystal Structure of Carboxyvinyl-Carboxyphosphonate Phosphorylmutase from Bacillus anthracis str. Ames Ancestor." Center for Structural Genomics of Infectious Diseases (CSGID) Kim Y., Maltseva N., Kwon K, Anderson W.F., Joachimiak A. Submitted (JAN-2013) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS).
[6]	"Crystal Structure of Carboxyvinyl-Carboxyphosphonate Phosphorylmutase from Bacillus anthracis." Center for Structural Genomics of Infectious Diseases (CSGID) Kim Y., Maltseva N., Kwon K, Anderson W.F., Joachimiak A. Submitted (JAN-2013) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE016879 Genomic DNA. Translation: AAP26219.1.
AE017334 Genomic DNA. Translation: AAT31469.1.
AE017225 Genomic DNA. Translation: AAT54502.1.

RefSeq

NP_844733.1. NC_003997.3.
YP_018994.1. NC_007530.2.
YP_028451.1. NC_005945.1.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
4IQD	X-ray	2.00	A/B	1-302	[»]
4IQE	X-ray	2.50	A/B	1-302	[»]

ModBase

Search...

Protein-protein interaction databases

STRING

198094.BA_2350.

Protocols and materials databases

DNASU

1089117.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAP26219; AAP26219; BA_2350.
AAT31469; AAT31469; GBAA_2350.
AAT54502; AAT54502; BAS2190.

GeneID

1089117.
2819611.
2849519.

KEGG

ban:BA_2350.
bar:GBAA_2350.
bat:BAS2190.

Phylogenomic databases

HOGENOM

HOG000220041.

KO

K01003.

OMA

GHRPGKA.

ProtClustDB

CLSK873755.

Enzyme and pathway databases

BioCyc

BANT260799:GJAJ-2256-MONOMER.
BANT261594:GJ7F-2334-MONOMER.

Family and domain databases

Gene3D

3.20.20.60. 1 hit.

InterPro

IPR018523. Isocitrate_lyase_ph_CS.
IPR012695. PrpB.
IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
[Graphical view]

SUPFAM

SSF51621. Pyrv/PenolPyrv_Kinase_cat. 1 hit.

TIGRFAMs

TIGR02317. prpB. 1 hit.

PROSITE

PS00161. ISOCITRATE_LYASE. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q81QR8.

Entry information

Entry name

Q81QR8_BACAN

Accession

Primary (citable) accession number: Q81QR8
Secondary accession number(s): E9R2D6 , E9R2D7, Q6HYY7, Q6KSY6

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 29, 2013
This is version 82 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)