Q81PL1 (RPIA_BACAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase A
EC=5.3.1.6

Alternative name(s):
Phosphoriboisomerase A
Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	BA_2791, GBAA_2791, BAS2602

Organism

Bacillus anthracis

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	220 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 220	220	Ribose-5-phosphate isomerase A HAMAP MF_00170		PRO_0000158382

Sequences

	Sequence		Length	Mass (Da)
	Q81PL1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: D334AE34C2944328	FASTA	220	23,979
	10 20 30 40 50 60 MDLKQIAGEY AATFVKDGMK IGLGTGSTAY WTIQKLGQRV KEGLSIQAVP TSKETEALAQ 70 80 90 100 110 120 QLNIPLISLN DVQSLDLTID GADEIDSNLQ LIKGGGGALL REKIVASSSK ELIIIVDESK 130 140 150 160 170 180 VVTRLGTFPL PIEIIPFAWK QTESKIQSLG CQTTLRLKNN ETFITDNNNM IIDCIFPNHI 190 200 210 220 PTPSDLHKRL KMITGVVETG LFVNMTSKAI IGTKNGIQEL

References

[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton.
[2]	"Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor.
[3]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne.
+	Additional computationally mapped references.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016879 Genomic DNA. Translation: AAP26626.1. AE017334 Genomic DNA. Translation: AAT31908.1. AE017225 Genomic DNA. Translation: AAT54912.1.
RefSeq	NP_845140.1. NC_003997.3. YP_019433.1. NC_007530.2. YP_028861.1. NC_005945.1.
3D structure databases
ProteinModelPortal	Q81PL1.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000009976; EBBACP00000009732; EBBACG00000009968. EBBACT00000015499; EBBACP00000015120; EBBACG00000015491. EBBACT00000022832; EBBACP00000022317; EBBACG00000022823.
GeneID	1088394. 2816795. 2850128.
GenomeReviews	Gene locus BA_2791 in contig AE016879_GR. Gene locus BAS2602 in contig AE017225_GR. Gene locus GBAA_2791 in contig AE017334_GR.
KEGG	ban:BA_2791. bar:GBAA_2791. bat:BAS2602.
TIGR	BA_2791. GBAA_2791.
Phylogenomic databases
GeneTree	EBGT00050000003998.
HOGENOM	HBG515603.
OMA	GGDPEYR.
ProtClustDB	PRK00702.
Enzyme and pathway databases
BioCyc	BANT260799:BAS2602-MONOMER. BANT261594:GBAA2791-MONOMER.
Family and domain databases
HAMAP	MF_00170. Rib_5P_isom_A. [Tree]
InterPro	IPR004788. Ribose5P_isomerase_typA. IPR020672. Ribose5P_isomerase_typA_subgr. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_BACAN

Accession

Primary (citable) accession number: Q81PL1
Secondary accession number(s): Q6HXS7, Q6KRU8

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 16, 2004
Last sequence update:	June 1, 2003
Last modified:	November 16, 2011
This is version 59 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program