Q81P86 (Q81P86_BACAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Submitted name:
Aminoglycoside N3-acetyltransferase EMBL AAP26752.1
EC=2.3.1.81 EMBL AAP26752.1

Gene names

Name:	aacC7 EMBL AAP26752.1
Ordered Locus Names:	BA_2930 EMBL AAP26752.1, GBAA_2930 EMBL AAT32047.1

Organism

Bacillus anthracis [Reference proteome] [HAMAP]

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

cellular organisms › Bacteria › Firmicutes › Bacilli › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	265 AA.
Sequence status	Complete.
Protein existence	Evidence at protein level

Ontologies

Keywords
Molecular function	Acyltransferase EMBL AAP26752.1 Transferase
Technical term	3D-structure PDB 3IJW PDB 3N0M PDB 3SLF PDB 3N0S PDB 3SLB Complete proteome Reference proteome
Gene Ontology (GO)
Biological_process	response to antibiotic Inferred from electronic annotation. Source: InterPro
Molecular_function	aminoglycoside 3-N-acetyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q81P86 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 4D116A8480798FF7	FASTA	265	29,608
	10 20 30 40 50 60 MNDIVASTQL PNTIKTITND LRKLGLKKGM TVIVHSSLSS IGWISGGAVA VVEALMEVIT 70 80 90 100 110 120 EEGTIIMPTQ SSDLSDPKHW SRPPVPEEWW QIIRDNVPAF EPHITPTRAM GKVVECFRTY 130 140 150 160 170 180 PNVVRSNHPL GSFAAWGRHA EEITVNQSLS MSLGEESPLR KIYDLDGYIL LIGVGYDSNT 190 200 210 220 230 240 SVHLSEVRSG ACELIKVGAP IIENGERVWK EFVDMDYDSD KFVEIGVEFE QKGTVTMGKI 250 260 GNAKCRLMKQ RDIVDFGTEW FRKKN

References

	« Hide 'large scale' referencesShow 'large scale' references »
[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames EMBL AAP26752.1 and Ames / isolate Porton.
[2]	"The complete genome sequence of Bacillus anthracis Ames "Ancestor"." Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A. J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor and Ames Ancestor EMBL AAT32047.1.
[3]	Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G. Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE. Strain: Ames EMBL AAP26752.1.
[4]	"Structural analysis of a putative aminoglycoside N-acetyltransferase from Bacillus anthracis." Klimecka M.M., Chruszcz M., Font J., Skarina T., Shumilin I., Onopryienko O., Porebski P.J., Cymborowski M., Zimmerman M.D., Hasseman J., Glomski I.J., Lebioda L., Savchenko A., Edwards A., Minor W. J. Mol. Biol. 410:411-423(2011) [PubMed] [Europe PMC] [Abstract] Cited for: X-RAY CRYSTALLOGRAPHY (1.90 ANGSTROMS).
[5]	"Crystal structure of BA2930 in complex with AcCoA and cytosine." Klimecka M.M., Chruszcz M., Porebski P.J., Cymborowski M., Anderson W., Minor W. Submitted (JUN-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.00 ANGSTROMS).
[6]	"Crystal structure of BA2930 in complex with AcCoA and uracil." Center for Structural Genomics of Infectious Diseases (CSGID) Klimecka M.M., Chruszcz M., Porebski P.J., Cymborowski M., Anderson W., Minor W. Submitted (JUN-2011) to the PDB data bank Cited for: X-RAY CRYSTALLOGRAPHY (2.05 ANGSTROMS).

Cross-references

Sequence databases

EMBL
GenBank
DDBJ

AE016879 Genomic DNA. Translation: AAP26752.1.
AE017334 Genomic DNA. Translation: AAT32047.1.

RefSeq

NP_845266.1. NC_003997.3.
YP_019572.1. NC_007530.2.

3D structure databases

PDBe
RCSB PDB
PDBj

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3IJW	X-ray	1.90	A/B	1-265	[»]
3N0M	X-ray	2.40	A/B	1-265	[»]
3N0S	X-ray	2.15	A/B/C/D	1-265	[»]
3SLB	X-ray	2.00	A/B/C/D	1-265	[»]
3SLF	X-ray	2.05	A/B	1-265	[»]

SMR

Q81P86. Positions 1-265.

ModBase

Search...

Protein-protein interaction databases

STRING

198094.BA_2930.

Protocols and materials databases

DNASU

1088452.

StructuralBiologyKnowledgebase

Search...

Genome annotation databases

EnsemblBacteria

AAP26752; AAP26752; BA_2930.
AAT32047; AAT32047; GBAA_2930.

GeneID

1088452.
2817536.

KEGG

ban:BA_2930.
bar:GBAA_2930.

PATRIC

18783470. VBIBacAnt69550_2910.

Phylogenomic databases

HOGENOM

HOG000030314.

KO

K00662.

OMA

EIDYNSE.

ProtClustDB

CLSK880970.

Enzyme and pathway databases

BioCyc

BANT261594:GJ7F-2892-MONOMER.

Family and domain databases

InterPro

IPR003679. Amioglycoside_AcTrfase.
[Graphical view]

Pfam

PF02522. Antibiotic_NAT. 1 hit.
[Graphical view]

ProtoNet

Search...

Other

EvolutionaryTrace

Q81P86.

Entry information

Entry name

Q81P86_BACAN

Accession

Primary (citable) accession number: Q81P86
Secondary accession number(s): E9R7S1, Q6KRH6

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	May 1, 2013
This is version 77 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)