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Protein

Glutaminase 2

Gene

glsA2

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamine + H2O = L-glutamate + NH3.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei73SubstrateUniRule annotation1
Binding sitei125SubstrateUniRule annotation1
Binding sitei169SubstrateUniRule annotation1
Binding sitei176SubstrateUniRule annotation1
Binding sitei200SubstrateUniRule annotation1
Binding sitei252SubstrateUniRule annotation1
Binding sitei270Substrate; via amide nitrogenUniRule annotation1

GO - Molecular functioni

  • glutaminase activity Source: TIGR

GO - Biological processi

Keywordsi

Molecular functionHydrolase

Names & Taxonomyi

Protein namesi
Recommended name:
Glutaminase 2UniRule annotation (EC:3.5.1.2UniRule annotation)
Gene namesi
Name:glsA2UniRule annotation
Synonyms:glsA-2
Ordered Locus Names:BA_3155, GBAA_3155, BAS2932
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome
  • UP000000427 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001105891 – 326Glutaminase 2Add BLAST326

Interactioni

Subunit structurei

Homotetramer.UniRule annotation

Protein-protein interaction databases

IntActiQ81NN0, 3 interactors
STRINGi260799.BAS2932

Structurei

3D structure databases

ProteinModelPortaliQ81NN0
SMRiQ81NN0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutaminase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CSV Bacteria
COG2066 LUCA
HOGENOMiHOG000216890
KOiK01425
OMAiMYTCGMY

Family and domain databases

HAMAPiMF_00313 Glutaminase, 1 hit
InterProiView protein in InterPro
IPR012338 Beta-lactam/transpept-like
IPR015868 Glutaminase
PANTHERiPTHR12544 PTHR12544, 1 hit
PfamiView protein in Pfam
PF04960 Glutaminase, 1 hit
SUPFAMiSSF56601 SSF56601, 1 hit
TIGRFAMsiTIGR03814 Gln_ase, 1 hit

Sequencei

Sequence statusi: Complete.

Q81NN0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MIKDSSVQVE GQEKVCLDQW VAHYRTYAAK GRSASYIPAL GEINVSQLGI
60 70 80 90 100
CIVKPDGTMI KSGDWEIPFT LQSISKVIGF IAACLSRGIS YVLERVDVEP
110 120 130 140 150
TGDAFNSIIR LEIHKPGKPF NPMINAGAIT IASLLPGTSV QEKLESIYVL
160 170 180 190 200
IEKMIEKRPA INEIVFQSEW ETAHRNRALA YYLKENGFLE SDVEETLEVY
210 220 230 240 250
LKQCSIEINT EDIALIGLIL AHDGYHPIRK EQVLPKEVAR LTKALMLTCG
260 270 280 290 300
MYNASGKFAA FIGLPAKSGV SGGIMTLVPS KSRKDLSFQD GCGIGIYGPA
310 320
IDEYGNSLPG IMLLEHIAKE WDLSIF
Length:326
Mass (Da):35,886
Last modified:June 1, 2003 - v1
Checksum:i923607E3522F53A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA Translation: AAP26958.1
AE017334 Genomic DNA Translation: AAT32270.1
AE017225 Genomic DNA Translation: AAT55241.1
RefSeqiNP_845472.1, NC_003997.3
WP_000588653.1, NZ_PPES01000033.1
YP_029190.1, NC_005945.1

Genome annotation databases

EnsemblBacteriaiAAP26958; AAP26958; BA_3155
AAT32270; AAT32270; GBAA_3155
AAT55241; AAT55241; BAS2932
GeneIDi1086611
2852277
KEGGiban:BA_3155
bar:GBAA_3155
bat:BAS2932
PATRICifig|198094.11.peg.3138

Similar proteinsi

Entry informationi

Entry nameiGLSA2_BACAN
AccessioniPrimary (citable) accession number: Q81NN0
Secondary accession number(s): Q6HWU8, Q6KQY6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: May 24, 2004
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 97 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families
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