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Q81N35

- Q81N35_BACAN

UniProt

Q81N35 - Q81N35_BACAN

Protein

Pyruvate kinase

Gene

pykA1

Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 98 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    ATP + pyruvate = ADP + phosphoenolpyruvate.UniRule annotation

    Pathwayi

    GO - Molecular functioni

    1. magnesium ion binding Source: InterPro
    2. potassium ion binding Source: InterPro
    3. pyruvate kinase activity Source: UniProtKB-EC

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-UniPathway

    Keywords - Molecular functioni

    KinaseUniRule annotationImported, Transferase

    Keywords - Biological processi

    GlycolysisUniRule annotation

    Keywords - Ligandi

    MagnesiumUniRule annotation, PyruvateImported

    Enzyme and pathway databases

    BioCyciBANT260799:GJAJ-3198-MONOMER.
    BANT261594:GJ7F-3307-MONOMER.
    UniPathwayiUPA00109; UER00188.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Pyruvate kinaseUniRule annotation (EC:2.7.1.40UniRule annotation)
    Gene namesi
    Name:pykA1Imported
    Ordered Locus Names:BA_3382Imported, BAS3136Imported, GBAA_3382Imported
    OrganismiBacillus anthracisImported
    Taxonomic identifieri1392 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000000594: Chromosome, UP000000427: Chromosome, UP000005639: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi198094.BA_3382.

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the pyruvate kinase family.UniRule annotation

    Phylogenomic databases

    HOGENOMiHOG000021558.
    KOiK00873.
    OMAiMAKICEE.
    OrthoDBiEOG6GBMB0.

    Family and domain databases

    Gene3Di2.40.33.10. 1 hit.
    3.20.20.60. 2 hits.
    InterProiIPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR011037. Pyrv_Knase-like_insert_dom.
    IPR015793. Pyrv_Knase_brl.
    IPR015806. Pyrv_Knase_insert_dom.
    [Graphical view]
    PANTHERiPTHR11817. PTHR11817. 1 hit.
    PfamiPF00224. PK. 1 hit.
    [Graphical view]
    PRINTSiPR01050. PYRUVTKNASE.
    SUPFAMiSSF50800. SSF50800. 1 hit.
    SSF51621. SSF51621. 2 hits.
    TIGRFAMsiTIGR01064. pyruv_kin. 1 hit.

    Sequencei

    Sequence statusi: Complete.

    Q81N35-1 [UniParc]FASTAAdd to Basket

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    MTIDRVCTIG PASNNKETLA KLINNGMKIV RLNLSHGTHE SHKDIIRLVK    50
    SLDDSIKILG DVQGPKIRLG EIKGEQITLQ AGDSFMLRTQ PVTGSSTEAS 100
    VDYEGIANDV KVGSRILMND GEVELIVEKV STDKIETKVK TGGNISSHKG 150
    VNLPGAIVSL PAITEKDKKD IQFLLEEDVD FIACSFVRKP SHIKEIRDFI 200
    QQYKETSPNL IAKIETMEAI ENFQDICKEA DGIMIARGDL GVELPYQFIP 250
    LLQKMMIQEC NRTNTYVITA TQMLQSMVDH SIPTRAEVTD VFQAVLDGTN 300
    AVMLSAESAS GEHPVESVST LRLVSEFAEH VKKDGPFVMK DVLELLHKSL 350
    DE 352
    Length:352
    Mass (Da):38,860
    Last modified:June 1, 2003 - v1
    Checksum:i94A73CAB2AB03E85
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016879 Genomic DNA. Translation: AAP27154.1.
    AE017334 Genomic DNA. Translation: AAT32490.1.
    AE017225 Genomic DNA. Translation: AAT55444.1.
    RefSeqiNP_845668.1. NC_003997.3.
    YP_020015.1. NC_007530.2.
    YP_029393.1. NC_005945.1.

    Genome annotation databases

    EnsemblBacteriaiAAP27154; AAP27154; BA_3382.
    AAT32490; AAT32490; GBAA_3382.
    AAT55444; AAT55444; BAS3136.
    GeneIDi1084882.
    2818907.
    2852562.
    KEGGiban:BA_3382.
    bar:GBAA_3382.
    bat:BAS3136.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016879 Genomic DNA. Translation: AAP27154.1 .
    AE017334 Genomic DNA. Translation: AAT32490.1 .
    AE017225 Genomic DNA. Translation: AAT55444.1 .
    RefSeqi NP_845668.1. NC_003997.3.
    YP_020015.1. NC_007530.2.
    YP_029393.1. NC_005945.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198094.BA_3382.

    Protocols and materials databases

    DNASUi 1084882.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP27154 ; AAP27154 ; BA_3382 .
    AAT32490 ; AAT32490 ; GBAA_3382 .
    AAT55444 ; AAT55444 ; BAS3136 .
    GeneIDi 1084882.
    2818907.
    2852562.
    KEGGi ban:BA_3382.
    bar:GBAA_3382.
    bat:BAS3136.

    Phylogenomic databases

    HOGENOMi HOG000021558.
    KOi K00873.
    OMAi MAKICEE.
    OrthoDBi EOG6GBMB0.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00188 .
    BioCyci BANT260799:GJAJ-3198-MONOMER.
    BANT261594:GJ7F-3307-MONOMER.

    Family and domain databases

    Gene3Di 2.40.33.10. 1 hit.
    3.20.20.60. 2 hits.
    InterProi IPR001697. Pyr_Knase.
    IPR015813. Pyrv/PenolPyrv_Kinase-like_dom.
    IPR011037. Pyrv_Knase-like_insert_dom.
    IPR015793. Pyrv_Knase_brl.
    IPR015806. Pyrv_Knase_insert_dom.
    [Graphical view ]
    PANTHERi PTHR11817. PTHR11817. 1 hit.
    Pfami PF00224. PK. 1 hit.
    [Graphical view ]
    PRINTSi PR01050. PYRUVTKNASE.
    SUPFAMi SSF50800. SSF50800. 1 hit.
    SSF51621. SSF51621. 2 hits.
    TIGRFAMsi TIGR01064. pyruv_kin. 1 hit.
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
      Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
      , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
      Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AmesImported, Ames ancestor and Sterne.
    2. "Complete genome sequence of Bacillus anthracis Sterne."
      Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
      Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ames / isolate PortonImported, Ames ancestorImported, Ames AncestorImported and SterneImported.
    4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
      Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: AmesImported.

    Entry informationi

    Entry nameiQ81N35_BACAN
    AccessioniPrimary (citable) accession number: Q81N35
    Secondary accession number(s): E9QRA9
    , E9QRB0, Q6HW95, Q6KQE6
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 98 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteomeImported

    External Data

    Dasty 3