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Protein

Transketolase

Gene

tkt1

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: -Protein inferred from homologyi

Functioni

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionTransferaseUniRule annotationSAAS annotationImported
LigandCalciumUniRule annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Thiamine pyrophosphateUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Recommended name:
TransketolaseUniRule annotation (EC:2.2.1.1UniRule annotation)
Gene namesi
Name:tkt1Imported
Ordered Locus Names:GBAA_3432Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

IntActiQ81MY7, 14 interactors
STRINGi260799.BAS3181

Structurei

3D structure databases

ProteinModelPortaliQ81MY7
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the transketolase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiCOG0021 LUCA
HOGENOMiHOG000225954
KOiK00615
OMAiTVEAYRF

Family and domain databases

Gene3Di3.40.50.920, 1 hit
InterProiView protein in InterPro
IPR029061 THDP-binding
IPR009014 Transketo_C/PFOR_II
IPR005475 Transketolase-like_Pyr-bd
IPR005478 Transketolase_bac-like
IPR020826 Transketolase_BS
IPR033248 Transketolase_C
IPR033247 Transketolase_fam
IPR005474 Transketolase_N
PANTHERiPTHR43522 PTHR43522, 1 hit
PfamiView protein in Pfam
PF02779 Transket_pyr, 1 hit
PF02780 Transketolase_C, 1 hit
PF00456 Transketolase_N, 1 hit
SMARTiView protein in SMART
SM00861 Transket_pyr, 1 hit
SUPFAMiSSF52518 SSF52518, 2 hits
SSF52922 SSF52922, 1 hit
TIGRFAMsiTIGR00232 tktlase_bact, 1 hit
PROSITEiView protein in PROSITE
PS00801 TRANSKETOLASE_1, 1 hit
PS00802 TRANSKETOLASE_2, 1 hit

Sequencei

Sequence statusi: Complete.

Q81MY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQNINQLAV NTIRTLSIDA INAANSGHPG LPMGAAPMAY ALWANHLNHN
60 70 80 90 100
PNHPKWFNRD RFVLSAGHGS SLLYSLLHLA GYDVSIDDLK NFRKLNSKTP
110 120 130 140 150
GHPEFGHTSG VEATTGPLGQ GIANAVGMAM AEAHLAAKFN KDGHSIIDHN
160 170 180 190 200
TYALVGDGDL MEGVAYEAMS MEGVAYEAMS MAGHMKLGKL IVLYDSNEIS
210 220 230 240 250
LDGELNIAFS EDMQKRVESA HWQYVRVEDG NDVDAITKAI QLAKDNTDQP
260 270 280 290 300
TLIEIRTVIG YGSPKVAGTN KAHGNPLGLE EATATKQVYG WHYEEDFFVP
310 320 330 340 350
EEVTAHFNEL KQKGIEKERG WNEQFNLYRE SNPALADELE KAIIGEVLIE
360 370 380 390 400
AKDILSFDSE KTISTRVASG EAINHYVKSI PSIFGGSADL SHSTMTDIKG
410 420 430 440 450
EAVYAVESYA GRNIYFGVRE HAMGAAANGL ALHGGVKPFV STFFVFNDYL
460 470 480 490 500
RPSIRLAALQ KLPVTYVFTH DSIAVGEDGP THEPIEHLAA LRAIPGLTVI
510 520 530 540 550
RPSDANETAS AWAYALQQTE GPVVLVLSRQ NLPVFHETKA NIENLSKGAY
560 570 580 590 600
VLTQTNENPD VILIATGSEV SLAASAKAKL EEDNVSVRIV AMPSWELFDR
610 620 630 640 650
QSKEYKESVL PSSVTKRVSL EMGVSLGWER YVGQEGNILS IETFGASGTG
660 670
AEVMNLFGFT TENVVQITKN VLNS
Length:674
Mass (Da):73,317
Last modified:June 1, 2003 - v1
Checksum:iAE89E6226BDA7549
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA Translation: AAT32542.1
RefSeqiWP_000193036.1, NZ_NRJB01000002.1

Genome annotation databases

EnsemblBacteriaiAAT32542; AAT32542; GBAA_3432
ANH87442; ANH87442; A8C77_16710
KEGGibar:GBAA_3432
PATRICifig|1392.232.peg.2544

Similar proteinsi

Entry informationi

Entry nameiQ81MY7_BACAN
AccessioniPrimary (citable) accession number: Q81MY7
Secondary accession number(s): E9QU09
, E9QU10, Q6HW50, Q6KQA6
Entry historyiIntegrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: March 28, 2018
This is version 128 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported
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Main funding by: National Institutes of Health