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Protein

Transketolase

Gene

tkt1

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.UniRule annotation

Catalytic activityi

Sedoheptulose 7-phosphate + D-glyceraldehyde 3-phosphate = D-ribose 5-phosphate + D-xylulose 5-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

TransferaseUniRule annotationSAAS annotationImported

Keywords - Ligandi

CalciumUniRule annotation, MagnesiumUniRule annotationSAAS annotation, Metal-bindingUniRule annotationSAAS annotation, Thiamine pyrophosphateUniRule annotationSAAS annotation

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3243-MONOMER.
BANT261594:GJ7F-3355-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
TransketolaseUniRule annotation (EC:2.2.1.1UniRule annotation)
Gene namesi
Name:tkt1Imported
Ordered Locus Names:GBAA_3432Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome

Interactioni

Subunit structurei

Homodimer.UniRule annotation

Protein-protein interaction databases

IntActiQ81MY7. 14 interactions.
STRINGi198094.BA_3432.

Family & Domainsi

Sequence similaritiesi

Belongs to the transketolase family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiCOG0021. LUCA.
HOGENOMiHOG000225954.
KOiK00615.
OMAiTVEAYRF.
OrthoDBiEOG6N3CRG.

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 3 hits.
InterProiIPR029061. THDP-binding.
IPR009014. Transketo_C/PFOR_II.
IPR005475. Transketolase-like_Pyr-bd.
IPR005478. Transketolase_bac-like.
IPR020826. Transketolase_BS.
IPR033248. Transketolase_C.
IPR033247. Transketolase_fam.
IPR005474. Transketolase_N.
[Graphical view]
PANTHERiPTHR11624. PTHR11624. 2 hits.
PfamiPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
SSF52922. SSF52922. 1 hit.
TIGRFAMsiTIGR00232. tktlase_bact. 1 hit.
PROSITEiPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81MY7-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MTQNINQLAV NTIRTLSIDA INAANSGHPG LPMGAAPMAY ALWANHLNHN
60 70 80 90 100
PNHPKWFNRD RFVLSAGHGS SLLYSLLHLA GYDVSIDDLK NFRKLNSKTP
110 120 130 140 150
GHPEFGHTSG VEATTGPLGQ GIANAVGMAM AEAHLAAKFN KDGHSIIDHN
160 170 180 190 200
TYALVGDGDL MEGVAYEAMS MEGVAYEAMS MAGHMKLGKL IVLYDSNEIS
210 220 230 240 250
LDGELNIAFS EDMQKRVESA HWQYVRVEDG NDVDAITKAI QLAKDNTDQP
260 270 280 290 300
TLIEIRTVIG YGSPKVAGTN KAHGNPLGLE EATATKQVYG WHYEEDFFVP
310 320 330 340 350
EEVTAHFNEL KQKGIEKERG WNEQFNLYRE SNPALADELE KAIIGEVLIE
360 370 380 390 400
AKDILSFDSE KTISTRVASG EAINHYVKSI PSIFGGSADL SHSTMTDIKG
410 420 430 440 450
EAVYAVESYA GRNIYFGVRE HAMGAAANGL ALHGGVKPFV STFFVFNDYL
460 470 480 490 500
RPSIRLAALQ KLPVTYVFTH DSIAVGEDGP THEPIEHLAA LRAIPGLTVI
510 520 530 540 550
RPSDANETAS AWAYALQQTE GPVVLVLSRQ NLPVFHETKA NIENLSKGAY
560 570 580 590 600
VLTQTNENPD VILIATGSEV SLAASAKAKL EEDNVSVRIV AMPSWELFDR
610 620 630 640 650
QSKEYKESVL PSSVTKRVSL EMGVSLGWER YVGQEGNILS IETFGASGTG
660 670
AEVMNLFGFT TENVVQITKN VLNS
Length:674
Mass (Da):73,317
Last modified:June 1, 2003 - v1
Checksum:iAE89E6226BDA7549
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA. Translation: AAT32542.1.
RefSeqiWP_000193036.1. NZ_LHUO01000006.1.

Genome annotation databases

EnsemblBacteriaiAAT32542; AAT32542; GBAA_3432.
KOM61447; KOM61447; AB168_15185.
KOM69465; KOM69465; AB166_08555.
KOM83613; KOM83613; AB164_21680.
KOR69368; KOR69368; ADT20_10325.
KEGGibar:GBAA_3432.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE017334 Genomic DNA. Translation: AAT32542.1.
RefSeqiWP_000193036.1. NZ_LHUO01000006.1.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ81MY7. 14 interactions.
STRINGi198094.BA_3432.

Protocols and materials databases

DNASUi1085597.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAT32542; AAT32542; GBAA_3432.
KOM61447; KOM61447; AB168_15185.
KOM69465; KOM69465; AB166_08555.
KOM83613; KOM83613; AB164_21680.
KOR69368; KOR69368; ADT20_10325.
KEGGibar:GBAA_3432.

Phylogenomic databases

eggNOGiCOG0021. LUCA.
HOGENOMiHOG000225954.
KOiK00615.
OMAiTVEAYRF.
OrthoDBiEOG6N3CRG.

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-3243-MONOMER.
BANT261594:GJ7F-3355-MONOMER.

Family and domain databases

Gene3Di3.40.50.920. 1 hit.
3.40.50.970. 3 hits.
InterProiIPR029061. THDP-binding.
IPR009014. Transketo_C/PFOR_II.
IPR005475. Transketolase-like_Pyr-bd.
IPR005478. Transketolase_bac-like.
IPR020826. Transketolase_BS.
IPR033248. Transketolase_C.
IPR033247. Transketolase_fam.
IPR005474. Transketolase_N.
[Graphical view]
PANTHERiPTHR11624. PTHR11624. 2 hits.
PfamiPF02779. Transket_pyr. 1 hit.
PF02780. Transketolase_C. 1 hit.
PF00456. Transketolase_N. 1 hit.
[Graphical view]
SMARTiSM00861. Transket_pyr. 1 hit.
[Graphical view]
SUPFAMiSSF52518. SSF52518. 2 hits.
SSF52922. SSF52922. 1 hit.
TIGRFAMsiTIGR00232. tktlase_bact. 1 hit.
PROSITEiPS00801. TRANSKETOLASE_1. 1 hit.
PS00802. TRANSKETOLASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames ancestorImported.

Entry informationi

Entry nameiQ81MY7_BACAN
AccessioniPrimary (citable) accession number: Q81MY7
Secondary accession number(s): E9QU09
, E9QU10, Q6HW50, Q6KQA6
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: July 6, 2016
This is version 115 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.