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Q81MS2 (SPEA_BACAN) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 77. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Arginine decarboxylase

EC=4.1.1.19
Gene names
Name:speA
Ordered Locus Names:BA_4172, GBAA_4172, BAS3874
OrganismBacillus anthracis [Reference proteome] [HAMAP]
Taxonomic identifier1392 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length493 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the formation of agmatine from arginine By similarity.

Catalytic activity

L-arginine = agmatine + CO2.

Cofactor

Pyridoxal phosphate By similarity.

Pathway

Amine and polyamine biosynthesis; agmatine biosynthesis; agmatine from L-arginine: step 1/1.

Subcellular location

Cytoplasm Probable.

Sequence similarities

Belongs to the Orn/Lys/Arg decarboxylase class-I family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 493493Arginine decarboxylase
PRO_0000201144

Amino acid modifications

Modified residue2291N6-(pyridoxal phosphate)lysine By similarity

Sequences

Sequence LengthMass (Da)Tools
Q81MS2 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 06215C0D777A73E8

FASTA49354,215
        10         20         30         40         50         60 
MYRLSQYETP LFTALVEHSK RNPIQFHIPG HKKGQGMDPE FREFIGHNAL AIDLINIAPL 

        70         80         90        100        110        120 
DDLHHPKGMI KEAQDLAAAA FGADHTFFSI QGTSGAIMTM VMSVCGPGDK ILVPRNVHKS 

       130        140        150        160        170        180 
VMSAIIFSGA KPIFMHPEID PKLGISHGIT IQSVKKALEE HSDAKGLLVI NPTYFGFAAD 

       190        200        210        220        230        240 
LEQIVQLAHS YDIPVLVDEA HGVHIHFHDE LPMSAMQAGA DMAATSVHKL GGSLTQSSIL 

       250        260        270        280        290        300 
NVKEGLVNVK HVQSIISMLT TTSTSYILLA SLDVARKRLA TEGKALIEQT IQLAEQVRNA 

       310        320        330        340        350        360 
INDIEHLYCP GKEMLGTDAT FNYDPTKIIV SVKDLGITGH QAEVWLREQY NIEVELSDLY 

       370        380        390        400        410        420 
NILCLVTFGD TESETNTLIA ALQDLSAIFK NKADKGVRIQ VEIPEIPVLA LSPRDAFYSE 

       430        440        450        460        470        480 
TEVIPFENAA GRIIADFVMV YPPGIPIFTP GEIITQDNLE YIRKNLEAGL PVQGPEDMTL 

       490 
QTLRVIKEYK PIS 

« Hide

References

[1]"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. expand/collapse author list , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames / isolate Porton.
[2]"The complete genome sequence of Bacillus anthracis Ames 'Ancestor'."
Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.
J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames ancestor.
[3]"Complete genome sequence of Bacillus anthracis Sterne."
Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sterne.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016879 Genomic DNA. Translation: AAP27896.1.
AE017334 Genomic DNA. Translation: AAT33294.1.
AE017225 Genomic DNA. Translation: AAT56175.1.
RefSeqNP_846410.1. NC_003997.3.
YP_020819.1. NC_007530.2.
YP_030124.1. NC_005945.1.

3D structure databases

ProteinModelPortalQ81MS2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

IntActQ81MS2. 5 interactions.
STRING198094.BA_4172.

Protocols and materials databases

DNASU1089028.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP27896; AAP27896; BA_4172.
AAT33294; AAT33294; GBAA_4172.
AAT56175; AAT56175; BAS3874.
GeneID1089028.
2818145.
2851739.
KEGGban:BA_4172.
bar:GBAA_4172.
bat:BAS3874.

Phylogenomic databases

eggNOGCOG1982.
HOGENOMHOG000083489.
KOK01582.
OMAHIQMELS.
OrthoDBEOG61CKX5.

Enzyme and pathway databases

BioCycBANT260799:GJAJ-3931-MONOMER.
BANT261594:GJ7F-4059-MONOMER.
UniPathwayUPA00186; UER00284.

Family and domain databases

Gene3D3.40.640.10. 1 hit.
3.90.100.10. 1 hit.
InterProIPR000310. Orn/Lys/Arg_deCO2ase_major_dom.
IPR008286. Prn/Lys/Arg_de-COase_C.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PfamPF01276. OKR_DC_1. 1 hit.
PF03711. OKR_DC_1_C. 1 hit.
[Graphical view]
SUPFAMSSF53383. SSF53383. 1 hit.
SSF55904. SSF55904. 1 hit.
PROSITEPS00703. OKR_DC_1. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameSPEA_BACAN
AccessionPrimary (citable) accession number: Q81MS2
Secondary accession number(s): Q6HU64, Q6KNE9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2004
Last sequence update: June 1, 2003
Last modified: May 14, 2014
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways