Q81MS1 (TGL_BACAN) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Protein-glutamine gamma-glutamyltransferase
EC=2.3.2.13

Alternative name(s):
Transglutaminase
Short name=TGase

Gene names

Name:	tgl
Ordered Locus Names:	BA_4173, GBAA_4173, BAS3875

Organism

Bacillus anthracis

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	276 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Probably plays a role in the assembly of the spore coat proteins by catalyzing epsilon-(gamma-glutamyl)lysine cross-links By similarity. HAMAP MF_00727
Catalytic activity	Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH3. HAMAP MF_00727
Sequence similarities	Belongs to the bacillus TGase family.

Ontologies

Keywords
Biological process	Sporulation
Molecular function	Acyltransferase Transferase
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	sporulation resulting in formation of a cellular spore Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	protein-glutamine gamma-glutamyltransferase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 276	276	Protein-glutamine gamma-glutamyltransferase HAMAP MF_00727		PRO_0000213722

Sequences

	Sequence		Length	Mass (Da)
	Q81MS1 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: 783EA7E21E9A3D30	FASTA	276	31,459
	10 20 30 40 50 60 MIVIGRSIVH PYITNEYEPF AAEKQQILSI MAGNQEIYSF RTSDELSFDL NLRVNIITSA 70 80 90 100 110 120 LELFQSGFQF RTFQQSFCNP QYWKRTSLGG FELLPNIPPS IAIQDIFKNG KLYGTECATA 130 140 150 160 170 180 MIIIFYKALL SLYEKETFNR LFANLLLYTW DYDQDLKLIT KTGGDLVPGD LVYFKNPQVN 190 200 210 220 230 240 PATIEWQGEN TIYLGNFFFY GHGVGVKTKE EIIYALNERR VPYAFISAFL TDTITRIDSR 250 260 270 LMSYHASPST PQTSIGFIPI RDDAIVATVG NTTTVY

References

[1]	"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton.
[2]	"Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor.
[3]	"Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016879 Genomic DNA. Translation: AAP27897.1. AE017334 Genomic DNA. Translation: AAT33295.1. AE017225 Genomic DNA. Translation: AAT56176.1.
RefSeq	NP_846411.1. NC_003997.3. YP_020820.1. NC_007530.2. YP_030125.1. NC_005945.1.
3D structure databases
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000010473; EBBACP00000010229; EBBACG00000010465. EBBACT00000018756; EBBACP00000018377; EBBACG00000018747. EBBACT00000024252; EBBACP00000023737; EBBACG00000024243.
GeneID	1088859. 2818146. 2851740.
GenomeReviews	Gene locus BA_4173 in contig AE016879_GR. Gene locus BAS3875 in contig AE017225_GR. Gene locus GBAA_4173 in contig AE017334_GR.
KEGG	ban:BA_4173. bar:GBAA_4173. bat:BAS3875.
TIGR	BA_4173. GBAA_4173.
Phylogenomic databases
GeneTree	EBGT00050000001129.
HOGENOM	HBG339895.
OMA	FECATAI.
ProtClustDB	PRK03187.
Enzyme and pathway databases
BioCyc	BANT260799:BAS3875-MONOMER. BANT261594:GBAA4173-MONOMER.
Family and domain databases
HAMAP	MF_00727. Tgl. [Tree]
InterPro	IPR020916. Gln_gamma-glutamylTfrase_bac. [Graphical view]
KO	K00686.
ProDom	PD119415. PD119415. 1 hit. [Graphical view] [Entries sharing at least one domain]
ProtoNet	Search...

Entry information

Entry name

TGL_BACAN

Accession

Primary (citable) accession number: Q81MS1
Secondary accession number(s): Q6HU63, Q6KNE8

Entry history

Integrated into UniProtKB/Swiss-Prot:	November 14, 2003
Last sequence update:	June 1, 2003
Last modified:	November 16, 2011
This is version 52 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program