ID   A0A2B6C3E8_BACAN        Unreviewed;       332 AA.
AC   A0A2B6C3E8; A0A1Q4M6S3; E9QX86; E9QX87; Q6HTS7; Q6KN14; Q81MC5;
DT   07-OCT-2020, integrated into UniProtKB/TrEMBL.
DT   07-OCT-2020, sequence version 1.
DT   27-MAR-2024, entry version 17.
DE   RecName: Full=Proline iminopeptidase {ECO:0000256|ARBA:ARBA00021843};
DE            EC=3.4.11.5 {ECO:0000256|ARBA:ARBA00012568};
DE   AltName: Full=Prolyl aminopeptidase {ECO:0000256|ARBA:ARBA00029605};
GN   OrderedLocusNames=GBAA_4324 {ECO:0000313|EMBL:AAT33446.1};
OS   Bacillus anthracis.
OC   Bacteria; Bacillota; Bacilli; Bacillales; Bacillaceae; Bacillus;
OC   Bacillus cereus group.
OX   NCBI_TaxID=1392 {ECO:0000313|EMBL:AAT33446.1, ECO:0000313|Proteomes:UP000000594};
RN   [1] {ECO:0000313|EMBL:AAT33446.1, ECO:0000313|Proteomes:UP000000594}
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Ames ancestor {ECO:0000313|Proteomes:UP000000594};
RX   PubMed=18952800; DOI=10.1128/JB.01347-08;
RA   Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D.,
RA   Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.;
RT   "The complete genome sequence of Bacillus anthracis Ames 'Ancestor'.";
RL   J. Bacteriol. 191:445-446(2009).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=Release of N-terminal proline from a peptide.; EC=3.4.11.5;
CC         Evidence={ECO:0000256|ARBA:ARBA00001585};
CC   -!- SIMILARITY: Belongs to the peptidase S33 family.
CC       {ECO:0000256|ARBA:ARBA00010088}.
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DR   EMBL; AE017334; AAT33446.1; -; Genomic_DNA.
DR   RefSeq; WP_000898981.1; NZ_WXXJ01000027.1.
DR   AlphaFoldDB; A0A2B6C3E8; -.
DR   IntAct; A0A2B6C3E8; 2.
DR   GeneID; 45023992; -.
DR   KEGG; bar:GBAA_4324; -.
DR   PATRIC; fig|1392.230.peg.4269; -.
DR   OMA; WFENSAH; -.
DR   OrthoDB; 53505at2; -.
DR   Proteomes; UP000000594; Chromosome.
DR   GO; GO:0004177; F:aminopeptidase activity; IEA:UniProtKB-KW.
DR   GO; GO:0006508; P:proteolysis; IEA:UniProtKB-KW.
DR   Gene3D; 3.40.50.1820; alpha/beta hydrolase; 1.
DR   InterPro; IPR029058; AB_hydrolase.
DR   InterPro; IPR000073; AB_hydrolase_1.
DR   InterPro; IPR002410; Peptidase_S33.
DR   PANTHER; PTHR43329:SF1; AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN; 1.
DR   PANTHER; PTHR43329; EPOXIDE HYDROLASE; 1.
DR   Pfam; PF00561; Abhydrolase_1; 1.
DR   PRINTS; PR00793; PROAMNOPTASE.
DR   SUPFAM; SSF53474; alpha/beta-Hydrolases; 1.
PE   3: Inferred from homology;
KW   Hydrolase {ECO:0000313|EMBL:AAT33446.1};
KW   Reference proteome {ECO:0000313|Proteomes:UP000000594}.
FT   DOMAIN          47..158
FT                   /note="AB hydrolase-1"
FT                   /evidence="ECO:0000259|Pfam:PF00561"
SQ   SEQUENCE   332 AA;  38270 MW;  CF149E930B4F808B CRC64;
     MLFRSYTPQF YNENKQPIPN SIATMESVMI NNRKQTLLIR GQNVEQPILL CCHGGPGMAQ
     IGFIRHFQKE LEKHFIVINW DQRGAGKSFS TKDFGANFTI EQFISDAKEV IQYVLKKFSK
     QKLFLAGHSW GSIIGLNIAH QYPQYIEAYI GIGQIVHMKQ NEELLYQHLI RSAKKHDHKK
     ALASLLKLGK PPFLDTRRLI IQRKWLGTFG GAIQNGSSFS FIRKGFFSPE YTLLDWFKFL
     AGNLKSGVLW EEMLTIDFFS SITSLSIPVY FCSGRYDYQT PYALVQEYCD VIEAPIKKMI
     WFPNSAHSPD LEEPELFAHS LQSIKQELAF QH
//