Reviewed,
UniProtKB/Swiss-Prot Q81M06 (GCST_BACAN)
Last modified
November 3, 2009.
Version 42.
History...
Clusters with 100%,
90%,
50% identity |
Documents (1) |
Third-party data |
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Names and origin
| Protein names | Recommended name: Aminomethyltransferase EC=2.1.2.10 Alternative name(s): Glycine cleavage system T protein | ||||
| Gene names |
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| Organism | Bacillus anthracis [Complete proteome] [HAMAP] | ||||
| Taxonomic identifier | 1392 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 366 AA. |
| Sequence status | Complete. |
| Sequence processing | The displayed sequence is not processed. |
| Protein existence | Inferred from homology. |
General annotation (Comments)
| Function | The glycine cleavage system catalyzes the degradation of glycine By similarity. |
| Catalytic activity | [Protein]-S(8)-aminomethyldihydrolipoyllysine + tetrahydrofolate = [protein]-dihydrolipoyllysine + 5,10-methylenetetrahydrofolate + NH3. HAMAP MF_00259 |
| Subunit structure | The glycine cleavage system is composed of four proteins: P, T, L and H By similarity. |
| Sequence similarities | Belongs to the gcvT family. |
Ontologies
| Keywords | |
|---|---|
| Molecular function | Aminotransferase Transferase |
| Technical term | Complete proteome |
| Gene Ontology (GO) | |
| Biological process | glycine decarboxylation via glycine cleavage system Inferred from electronic annotation. Source: HAMAP |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: InterPro |
| Molecular function | aminomethyltransferase activity Inferred from electronic annotation. Source: HAMAP transaminase activityInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 366 | 366 | Aminomethyltransferase HAMAP MF_00259 | PRO_0000122535 | |||
Sequences
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References
| [1] | "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. Fraser C.M.Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton. |
| [2] | "Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor. |
| [3] | "Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne. |
Cross-references
Sequence databases | |
|---|---|
| AE016879 Genomic DNA. Translation: AAP28163.1. AE017334 Genomic DNA. Translation: AAT33568.1. AE017225 Genomic DNA. Translation: AAT56431.1. | |
| RefSeq | NP_846677.1. YP_021093.1. YP_030380.1. |
3D structure databases | |
| ModBase | Search... |
Genome annotation databases | |
| GeneID | 1087845. 2818765. 2849651. |
| GenomeReviews | Gene locus BA_4449 in contig AE016879_GR. Gene locus BAS4131 in contig AE017225_GR. Gene locus GBAA_4449 in contig AE017334_GR. |
| KEGG | ban:BA4449. bar:GBAA4449. bat:BAS4131. |
| TIGR | BA_4449. GBAA_4449. |
Phylogenomic databases | |
| HOGENOM | Q81M06. |
| OMA | LMTNDIN. |
Enzyme and pathway databases | |
| BioCyc | BANT260799:BAS4131-MON. BANT261594:GBAA4449-MON. |
| BRENDA | 2.1.2.10. 267517. |
Family and domain databases | |
| HAMAP | MF_00259. [Tree] |
| InterPro | IPR013977. GCV_T_C. IPR006222. GCV_T_N. IPR006223. GcvT. [Graphical view] |
| Pfam | PF01571. GCV_T. 1 hit. PF08669. GCV_T_C. 1 hit. [Graphical view] |
| PIRSF | PIRSF006487. GcvT. 1 hit. |
| TIGRFAMs | TIGR00528. gcvT. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | GCST_BACAN | ||||||||
| Accession | Primary (citable) accession number: Q81M06 Secondary accession number(s): Q6HTF8, Q6KMQ1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation project | HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes) | ||||||||

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