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Protein

L-cystine uptake protein TcyP

Gene

BA_4469

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Mediates uptake of L-cystine, the oxidized form of L-cysteine.By similarity

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Biological processi

Amino-acid transport, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
L-cystine uptake protein TcyP
Alternative name(s):
Transporter of cystine TcyP
Gene namesi
Ordered Locus Names:BA_4469, GBAA_4469, BAS4148
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome

Subcellular locationi

Topology

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Transmembranei3 – 23HelicalSequence analysisAdd BLAST21
Transmembranei34 – 54HelicalSequence analysisAdd BLAST21
Transmembranei73 – 93HelicalSequence analysisAdd BLAST21
Transmembranei107 – 127HelicalSequence analysisAdd BLAST21
Transmembranei184 – 204HelicalSequence analysisAdd BLAST21
Transmembranei225 – 245HelicalSequence analysisAdd BLAST21
Transmembranei263 – 283HelicalSequence analysisAdd BLAST21
Transmembranei347 – 367HelicalSequence analysisAdd BLAST21
Transmembranei371 – 391HelicalSequence analysisAdd BLAST21
Transmembranei395 – 415HelicalSequence analysisAdd BLAST21

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Membrane

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00002797351 – 464L-cystine uptake protein TcyPAdd BLAST464

Interactioni

Protein-protein interaction databases

IntActiQ81LY8. 1 interactor.
STRINGi198094.BA_4469.

Structurei

3D structure databases

ProteinModelPortaliQ81LY8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Keywords - Domaini

Transmembrane, Transmembrane helix

Phylogenomic databases

eggNOGiCOG1823. LUCA.
HOGENOMiHOG000208777.
KOiK06956.
OMAiMLAMMIA.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81LY8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MNTLLVGINV AVMLILVGVL YYMQRKHVSF NKRVFTALGI GIIFGLILQF
60 70 80 90 100
IYEPTSKVII ESNTWFGLIG SGYVKLLQMI VMPLILVSII SAFTKLQLTK
110 120 130 140 150
NLGKISGLII GILILTTGIA AAVGIAASAG FDVSATGLQQ GDAESARLKL
160 170 180 190 200
VEERFTSIEK TTIPDKLLEL LPTNPFLDLT GARPTSTISV VIFAAFIGIA
210 220 230 240 250
FIGVKRKYPE QAELFKKMLD AVYAIVMRMV TLILRLTPYG VLALMAKTVA
260 270 280 290 300
GSDINAILKL GNFVLASYVA LIVMFVIHLL LIALSGLNPI QYLKKVFPVL
310 320 330 340 350
TFAFTSRSSA GAMPLNIEAQ KEKLGISEGI ANFAASFGVS IGQNGCAGIY
360 370 380 390 400
PAMLAMMVAP TVGIDPLQPQ FILTLIAVVA ISSFGVAGVG GGATFAALIV
410 420 430 440 450
LSTMNLPIGI VALVISVEPL IDMGRTALNV SGSMTAGLIS SKWLGELDQD
460
TYNQDDTKTG EIAS
Length:464
Mass (Da):49,256
Last modified:June 1, 2003 - v1
Checksum:i6B784976A4D13A59
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28181.1.
AE017334 Genomic DNA. Translation: AAT33587.1.
AE017225 Genomic DNA. Translation: AAT56448.1.
RefSeqiNP_846695.1. NC_003997.3.
WP_001094329.1. NZ_LHUO01000006.1.
YP_030397.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP28181; AAP28181; BA_4469.
AAT33587; AAT33587; GBAA_4469.
AAT56448; AAT56448; BAS4148.
GeneIDi1087914.
2849790.
KEGGiban:BA_4469.
bar:GBAA_4469.
bat:BAS4148.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28181.1.
AE017334 Genomic DNA. Translation: AAT33587.1.
AE017225 Genomic DNA. Translation: AAT56448.1.
RefSeqiNP_846695.1. NC_003997.3.
WP_001094329.1. NZ_LHUO01000006.1.
YP_030397.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81LY8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ81LY8. 1 interactor.
STRINGi198094.BA_4469.

Protocols and materials databases

DNASUi1087914.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP28181; AAP28181; BA_4469.
AAT33587; AAT33587; GBAA_4469.
AAT56448; AAT56448; BAS4148.
GeneIDi1087914.
2849790.
KEGGiban:BA_4469.
bar:GBAA_4469.
bat:BAS4148.

Phylogenomic databases

eggNOGiCOG1823. LUCA.
HOGENOMiHOG000208777.
KOiK06956.
OMAiMLAMMIA.

Family and domain databases

Gene3Di1.10.3860.10. 1 hit.
InterProiIPR001991. Na-dicarboxylate_symporter.
[Graphical view]
PANTHERiPTHR11958. PTHR11958. 1 hit.
PfamiPF00375. SDF. 1 hit.
[Graphical view]
PRINTSiPR00173. EDTRNSPORT.
SUPFAMiSSF118215. SSF118215. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiTCYP_BACAN
AccessioniPrimary (citable) accession number: Q81LY8
Secondary accession number(s): Q6HTE1, Q6KMN3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 6, 2007
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 94 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.