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Protein

Superoxide dismutase [Mn] 1

Gene

sodA1

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarityNote: Binds 1 Mn2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi28ManganeseBy similarity1
Metal bindingi83ManganeseBy similarity1
Metal bindingi165ManganeseBy similarity1
Metal bindingi169ManganeseBy similarity1

GO - Molecular functioni

GO - Biological processi

  • removal of superoxide radicals Source: TIGR

Keywordsi

Molecular functionOxidoreductase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn] 1 (EC:1.15.1.1)
Gene namesi
Name:sodA1
Synonyms:sodA-1
Ordered Locus Names:BA_4499, GBAA_4499, BAS4177
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome
  • UP000000427 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001600121 – 203Superoxide dismutase [Mn] 1Add BLAST203

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi260799.BAS4177

Structurei

Secondary structure

1203
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni13 – 19Combined sources7
Helixi22 – 30Combined sources9
Helixi32 – 44Combined sources13
Helixi48 – 51Combined sources4
Helixi55 – 60Combined sources6
Helixi62 – 64Combined sources3
Helixi67 – 88Combined sources22
Helixi100 – 110Combined sources11
Helixi113 – 126Combined sources14
Beta strandi129 – 138Combined sources10
Beta strandi141 – 148Combined sources8
Helixi153 – 156Combined sources4
Beta strandi159 – 165Combined sources7
Helixi168 – 170Combined sources3
Helixi172 – 175Combined sources4
Helixi179 – 186Combined sources8
Turni187 – 189Combined sources3
Helixi192 – 201Combined sources10

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XUQX-ray1.80A/B1-203[»]
ProteinModelPortaliQ81LW0
SMRiQ81LW0
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ81LW0

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4 Bacteria
COG0605 LUCA
HOGENOMiHOG000013583
KOiK04564
OMAiYEGWKGE

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Q81LW0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAKHELPNLP YAYDALEPHF DKETMNIHHT KHHNTYITNL NAALEGHAEL
60 70 80 90 100
ADKSVEELVA NLNEVPEAIR TAVRNNGGGH ANHTFFWTIL SPNGGGQPVG
110 120 130 140 150
ELATAIEAKF GSFDAFKEEF AKAGATRFGS GWAWLVVNNG ELEVTSTPNQ
160 170 180 190 200
DSPLTEGKTP VIGLDVWEHA YYLNYQNRRP DYIGAFWNVV DWNAAEKRYQ

EAK
Length:203
Mass (Da):22,664
Last modified:June 1, 2003 - v1
Checksum:i61B0B7D44A090D97
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA Translation: AAP28210.1
AE017334 Genomic DNA Translation: AAT33618.1
AE017225 Genomic DNA Translation: AAT56477.1
RefSeqiNP_846724.1, NC_003997.3
WP_001052031.1, NZ_PPES01000001.1
YP_030426.1, NC_005945.1

Genome annotation databases

EnsemblBacteriaiAAP28210; AAP28210; BA_4499
AAT33618; AAT33618; GBAA_4499
AAT56477; AAT56477; BAS4177
GeneIDi1088022
2851955
31628265
KEGGiban:BA_4499
bar:GBAA_4499
bat:BAS4177
PATRICifig|198094.11.peg.4467

Similar proteinsi

Entry informationi

Entry nameiSODM1_BACAN
AccessioniPrimary (citable) accession number: Q81LW0
Secondary accession number(s): Q6HTB2, Q6KMK4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 105 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome

Documents

  1. PDB cross-references
    Index of Protein Data Bank (PDB) cross-references
  2. SIMILARITY comments
    Index of protein domains and families

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