Skip Header

 
Contribute Send feedback
Read comments (0) or add your own

Reviewed, UniProtKB/Swiss-Prot Q81LA9 (RNPH_BACAN)

Last modified November 3, 2009. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Hide | Top

Names and origin

Protein namesRecommended name:
    Ribonuclease PH
      Short name=RNase PH
    EC=2.7.7.56
Alternative name(s):
    tRNA nucleotidyltransferase
Gene names
Name: rph
Ordered Locus Names: BA_4715, GBAA_4715, BAS4377
OrganismBacillus anthracis [Complete proteome] [HAMAP]
Taxonomic identifier1392 [NCBI]
Taxonomic lineageBacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Hide | Top

Protein attributes

Sequence length245 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceEvidence at protein level.

Hide | Top

General annotation (Comments)

Function

Phosphorolytic exoribonuclease that removes nucleotide residues following the -CCA terminus of tRNA and adds nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates By similarity.

Catalytic activity

tRNA(n+1) + phosphate = tRNA(n) + a nucleoside diphosphate. HAMAP MF_00564

Sequence similarities

Belongs to the RNase PH family.

Hide | Top

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 245245Ribonuclease PH HAMAP MF_00564
PRO_0000139862

Secondary structure

1 ............................................. 245
Helix Strand Turn

Details...

Hide | Top

Sequences

Sequence LengthMass (Da)Tools
Q81LA9-1 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 00053DA2C582D0E6

FASTA24526,983
        10         20         30         40         50         60 
MRVDGREKTE LRHIHIHTNY LKHPEGSVLI EVGDTKVICS ATIEERVPPF MRGEGKGWVT 

        70         80         90        100        110        120 
AEYAMIPRAT EQRTIRESSK GKVTGRTMEI QRLIGRALRA VVDLEALGER TVWIDCDVIQ 

       130        140        150        160        170        180 
ADGGTRTASI TGAYVAMVLA FEKLLQAEKV SKIPVKDYLA ATSVGIVEEQ GVVLDLNYAE 

       190        200        210        220        230        240 
DSKADVDMNV IMTGKGQFVE VQGTGEEATF SRAQLNELLD AAEQGIFQLI DIQKEALGDI 


VSHIE

« Hide

Hide | Top

References

[1]"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. expand/collapse author list , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
Nature 423:81-86(2003) [PubMed: 12721629] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames / isolate Porton.
[2]"Bacillus anthracis comparative genomics."
Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M.
Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames ancestor.
[3]"Complete genome sequence of Bacillus anthracis Sterne."
Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sterne.
+Additional computationally mapped references.

Hide | Top

Cross-references

Sequence databases

AE016879 Genomic DNA. Translation: AAP28413.1.
AE017334 Genomic DNA. Translation: AAT33839.1.
AE017225 Genomic DNA. Translation: AAT56675.1.
RefSeqNP_846927.1.
YP_021364.1.
YP_030624.1.

3D structure databases

EntryMethodResolution (Å)ChainPositionsPDBsum
3DD6X-ray1.70A1-245[»]
SMRQ81LA9. Positions 1-239.
ModBaseSearch...

Genome annotation databases

GeneID1088544.
2815981.
2851699.
GenomeReviewsGene locus BA_4715 in contig AE016879_GR.
Gene locus BAS4377 in contig AE017225_GR.
Gene locus GBAA_4715 in contig AE017334_GR.
KEGGban:BA4715.
bar:GBAA4715.
bat:BAS4377.
TIGRBA_4715.
GBAA_4715.

Phylogenomic databases

HOGENOMQ81LA9.
OMAYAMLPRA.

Enzyme and pathway databases

BioCycBANT260799:BAS4377-MON.
BANT261594:GBAA4715-MON.
BRENDA2.7.7.56. 267517.

Family and domain databases

HAMAPMF_00564.
[Tree]
InterProIPR001247. ExoRNase_PH_dom1.
IPR015847. ExoRNase_PH_dom2.
IPR018336. Ribonuclease-PH_CS.
IPR002381. RNase_PH_bac-type.
[Graphical view]
PfamPF01138. RNase_PH. 1 hit.
PF03725. RNase_PH_C. 1 hit.
[Graphical view]
TIGRFAMsTIGR01966. RNasePH. 1 hit.
PROSITEPS01277. RIBONUCLEASE_PH. 1 hit.
[Graphical view]
ProtoNetSearch...

Hide | Top

Entry information

Entry nameRNPH_BACAN
AccessionPrimary (citable) accession number: Q81LA9
Secondary accession number(s): Q6HSR4, Q6KM05
Entry history
Integrated into UniProtKB/Swiss-Prot: March 15, 2005
Last sequence update: June 1, 2003
Last modified: November 3, 2009
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Hide | Top

Relevant documents

PDB cross-references

Index of Protein Data Bank (PDB) cross-references

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents