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Q81L45

- Q81L45_BACAN

UniProt

Q81L45 - Q81L45_BACAN

Protein
Submitted name:

Iron Transport-associated domain protein

Gene

BA_4787

Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli
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    • History
      Entry version 84 (01 Oct 2014)
      Sequence version 1 (01 Jun 2003)
      Previous versions | rss
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    Functioni

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Metal bindingi700 – 7001Iron (heme axial ligand)Imported
    Metal bindingi782 – 7821Iron (heme axial ligand)Imported

    GO - Molecular functioni

    1. metal ion binding Source: UniProtKB-KW

    Keywords - Ligandi

    HemeImported, Iron, Metal-binding

    Enzyme and pathway databases

    BioCyciBANT260799:GJAJ-4499-MONOMER.
    BANT261594:GJ7F-4650-MONOMER.

    Names & Taxonomyi

    Protein namesi
    Submitted name:
    Iron Transport-associated domain proteinImported
    Submitted name:
    Uncharacterized proteinImported
    Gene namesi
    Ordered Locus Names:BA_4787Imported, BAS4442Imported, GBAA_4787Imported
    OrganismiBacillus anthracisImported
    Taxonomic identifieri1392 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
    ProteomesiUP000000594: Chromosome, UP000000427: Chromosome, UP000005639: Chromosome

    Interactioni

    Protein-protein interaction databases

    STRINGi198094.BA_4787.

    Structurei

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    EntryMethodResolution (Å)ChainPositionsPDBsum
    4H8PX-ray2.05A675-797[»]
    4H8QX-ray1.70A675-797[»]
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Phylogenomic databases

    HOGENOMiHOG000097555.
    OMAiKQPDGDK.
    OrthoDBiEOG68SVXG.

    Family and domain databases

    InterProiIPR006635. NEAT_dom.
    IPR017502. Sortase_SrtB_target.
    [Graphical view]
    PfamiPF05031. NEAT. 5 hits.
    [Graphical view]
    SMARTiSM00725. NEAT. 5 hits.
    [Graphical view]
    TIGRFAMsiTIGR03063. srtB_target. 1 hit.
    PROSITEiPS50978. NEAT. 5 hits.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Q81L45-1 [UniParc]FASTAAdd to Basket

    « Hide

    MNRYTKIIVA MFLMIFTFVS TLQPLAVQAA TKLADGEYSI GFKVLKDTSD    50
    EESMMNQYSV SPGTLKVKDG KKKVSFTLTN SSWITKFETE KAGKLVATNV 100
    ISEDKEKDTR VVEFDVEDVE KVLNAKVKVD IDFLNYHHEY DVRIAFDQNS 150
    ITPIHVEQPN EKEDPANKPD PNEKPDPSQK PDQKPDPDQQ PNSNTIKDGE 200
    YSIPFKVLKN QTDEESKMNT YMVNPGVLKI ENGKKKAIVT LKSSSLIKNF 250
    QTEKDGAFVD AKVVSENKEK DTRVVEFEVA DLSKKLNTKV FIEMASRNYK 300
    QTHDVQLLFE QDKLEQIKNE EKQPEVEKPE VEKPEVEKPE VEKPDENKKT 350
    DAETIKDGEY SINFKALKDQ TDEISMMNTY TKSPGLLKVK DGKKYVSFTL 400
    TNSSWITKFE FEKNGSFVDA NVISEDKKAD TRVVEVAVDD LSKKLNAKVK 450
    VDIDSMNYHH FYDIQFAFDK GSIKPLDNQG GNDNQGGNNN QGGNNNHDDN 500
    KTIDPNALKD GEYSIGFKVL KDKTEEISMM NTYTKNPGVL KVKDGKKYVS 550
    FTLTNSSWIT KFEFEKNGAF VDAKVLGTNK EQDTRVVEVE VADLSKKLNA 600
    KVKVDIDSMN YHHFYDIQFA FDKGSIKSLG NQGGDTNQDG NGNQGGNDNQ 650
    GGSNNQDDNN NQDGTNNLNE NPTVDPKNLK DGQYDIAFKV LKDKTEEISM 700
    MNQYVVSPAR LTVKDGKKYI AMTLKNSEWI TKFQTEKNGG FADAKVVSED 750
    KAANTRVVEF EANDLFAKLN AKVKVDIDSM NYHHFYDVQI QFDPTKIGAV 800
    GTVKEEPKNE PKNPVITPKV DNVKTIATPD FNRNADGKKK NEATNNDAKK 850
    EKNSKTADTA QLGLYMVLLL GSLALLVRKY RAGRL 885
    Length:885
    Mass (Da):99,611
    Last modified:June 1, 2003 - v1
    Checksum:iE4FE550B98512D57
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016879 Genomic DNA. Translation: AAP28478.1.
    AE017334 Genomic DNA. Translation: AAT35435.1.
    AE017225 Genomic DNA. Translation: AAT56740.1.
    RefSeqiNP_846992.1. NC_003997.3.
    YP_022701.1. NC_007530.2.
    YP_030689.1. NC_005945.1.

    Genome annotation databases

    EnsemblBacteriaiAAP28478; AAP28478; BA_4787.
    AAT35435; AAT35435; GBAA_4787.
    AAT56740; AAT56740; BAS4442.
    GeneIDi1088310.
    2815654.
    2851614.
    KEGGiban:BA_4787.
    bar:GBAA_4787.
    bat:BAS4442.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    AE016879 Genomic DNA. Translation: AAP28478.1 .
    AE017334 Genomic DNA. Translation: AAT35435.1 .
    AE017225 Genomic DNA. Translation: AAT56740.1 .
    RefSeqi NP_846992.1. NC_003997.3.
    YP_022701.1. NC_007530.2.
    YP_030689.1. NC_005945.1.

    3D structure databases

    Select the link destinations:
    PDBe
    RCSB PDB
    PDBj
    Links Updated
    Entry Method Resolution (Å) Chain Positions PDBsum
    4H8P X-ray 2.05 A 675-797 [» ]
    4H8Q X-ray 1.70 A 675-797 [» ]
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 198094.BA_4787.

    Protocols and materials databases

    DNASUi 1088310.
    Structural Biology Knowledgebase Search...

    Genome annotation databases

    EnsemblBacteriai AAP28478 ; AAP28478 ; BA_4787 .
    AAT35435 ; AAT35435 ; GBAA_4787 .
    AAT56740 ; AAT56740 ; BAS4442 .
    GeneIDi 1088310.
    2815654.
    2851614.
    KEGGi ban:BA_4787.
    bar:GBAA_4787.
    bat:BAS4442.

    Phylogenomic databases

    HOGENOMi HOG000097555.
    OMAi KQPDGDK.
    OrthoDBi EOG68SVXG.

    Enzyme and pathway databases

    BioCyci BANT260799:GJAJ-4499-MONOMER.
    BANT261594:GJ7F-4650-MONOMER.

    Family and domain databases

    InterProi IPR006635. NEAT_dom.
    IPR017502. Sortase_SrtB_target.
    [Graphical view ]
    Pfami PF05031. NEAT. 5 hits.
    [Graphical view ]
    SMARTi SM00725. NEAT. 5 hits.
    [Graphical view ]
    TIGRFAMsi TIGR03063. srtB_target. 1 hit.
    PROSITEi PS50978. NEAT. 5 hits.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
      Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
      , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
      Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: AmesImported, Ames ancestor and Sterne.
    2. "Complete genome sequence of Bacillus anthracis Sterne."
      Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
      Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: Ames / isolate PortonImported, Ames AncestorImported, Ames ancestorImported and SterneImported.
    4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
      Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
      Cited for: NUCLEOTIDE SEQUENCE.
      Strain: AmesImported.
    5. "The near-iron transporter (NEAT) domains of the anthrax hemophore IsdX2 require a critical glutamine to extract heme from methemoglobin."
      Honsa E.S., Owens C.P., Goulding C.W., Maresso A.W.
      J. Biol. Chem. 288:8479-8490(2013) [PubMed] [Europe PMC] [Abstract]
      Cited for: X-RAY CRYSTALLOGRAPHY (1.70 ANGSTROMS) OF 675-797 IN COMPLEX WITH HEME.

    Entry informationi

    Entry nameiQ81L45_BACAN
    AccessioniPrimary (citable) accession number: Q81L45
    Secondary accession number(s): E9QZH0
    , E9QZH1, Q6HSJ9, Q6KIY5
    Entry historyi
    Integrated into UniProtKB/TrEMBL: June 1, 2003
    Last sequence update: June 1, 2003
    Last modified: October 1, 2014
    This is version 84 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiUnreviewed (UniProtKB/TrEMBL)

    Miscellaneousi

    Keywords - Technical termi

    3D-structureImported, Complete proteome, Reference proteomeImported

    External Data

    Dasty 3