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Protein
Submitted name:

AMP-binding enzyme family protein

Gene

acsA

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. acetate-CoA ligase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciANTHRA:ACSA-MONOMER.
BANT260799:GJAJ-4617-MONOMER.
BANT261594:GJ7F-4774-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
AMP-binding enzyme family proteinImported
Submitted name:
Acetate--CoA ligaseImported (EC:6.2.1.1Imported)
Submitted name:
Acetyl-CoA synthetaseImported (EC:6.2.1.1Imported)
Gene namesi
Name:acsAImported
Ordered Locus Names:BA_4915Imported, BAS4560Imported, GBAA_4915Imported
ORF Names:BD64_791Imported, BF24_2346Imported, BF25_31Imported, BF26_3789Imported, BF31_1987Imported, BF37_2375Imported, BF39_3496Imported, BF89_3332Imported, BF90_2634Imported, BG01_462Imported, BG02_1883Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000005639 Componenti: Chromosome UP000000594 Componenti: Chromosome UP000000427 Componenti: Chromosome

Interactioni

Protein-protein interaction databases

IntActiQ81KS5. 3 interactions.
STRINGi198094.BA_4915.

Structurei

3D structure databases

ProteinModelPortaliQ81KS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000229981.
KOiK01895.
OMAiCYWQTET.
OrthoDBiEOG68WR2H.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81KS5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKVETLPVIK GENNLPNYDE AYANFNWEEV NKNFTWNEAG RVNMAYEAID
60 70 80 90 100
KHAKSDRKNK VALYYQDGSR KEKYTFKEMK DFSNKAGNVL KNYGDVEKGD
110 120 130 140 150
RVFIFMPRSP ELYFALLGAV KLGAIVGPLF EAFMEGAVRD RLEDSEAKVL
160 170 180 190 200
ITTPELLERV PLNDLPALKT VFLVGDHVEE GGKTVAFNPL FEQASKELHI
210 220 230 240 250
EWLGREDGLI LHYTSGSTGK PKGVLHAQNA MVQHYQTAKW VLDLKEDDVY
260 270 280 290 300
WCTADPGWVT GTAYGIFAPW LVGASNVILG GRFSPEAWYE ALQDYGVTVW
310 320 330 340 350
YSAPTAFRML MGAGQDAIKK YDLSQVRHVL SVGEPLNPEV IRWGMNAFGL
360 370 380 390 400
RIHDTWWMTE TGGQVICNYP CMEIRPGSMG KPIPGVKAAI VDNEGNEVPP
410 420 430 440 450
YTMGNLAIGK GWPAMMRGIW NNKQKYESYF MPGDWYVSGD SAYMDEDGYF
460 470 480 490 500
WFQGRIDDVI MTSGERVGPF EVESKLIEHA AVAEAGVIGI PDPVRGEIIK
510 520 530 540 550
AFIALRAGYE PSEELKEEIR QFVKKGLAAH AAPRQIEFRD KLPKTRSGKI
560 570
MRRVLKAWEL NLPTGDLSTM ED
Length:572
Mass (Da):64,344
Last modified:June 1, 2003 - v1
Checksum:i13544565E6D06662
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28599.1.
AE017334 Genomic DNA. Translation: AAT34033.1.
AE017225 Genomic DNA. Translation: AAT56857.1.
CP009325 Genomic DNA. Translation: AJG67000.1.
CP009331 Genomic DNA. Translation: AJG69784.1.
CP009328 Genomic DNA. Translation: AJG85081.1.
CP009341 Genomic DNA. Translation: AJG88366.1.
CP009464 Genomic DNA. Translation: AJH31437.1.
CP009476 Genomic DNA. Translation: AJH33065.1.
CP009697 Genomic DNA. Translation: AJH41767.1.
CP009544 Genomic DNA. Translation: AJH51007.1.
CP009700 Genomic DNA. Translation: AJH55049.1.
CP009981 Genomic DNA. Translation: AJH92859.1.
CP010322 Genomic DNA. Translation: AJI39945.1.
RefSeqiNP_847113.1. NC_003997.3.
WP_000862038.1. NZ_KN050651.1.
YP_021558.1. NC_007530.2.
YP_030807.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP28599; AAP28599; BA_4915.
AAT34033; AAT34033; GBAA_4915.
AAT56857; AAT56857; BAS4560.
GeneIDi1086714.
2848558.
KEGGiban:BA_4915.
bar:GBAA_4915.
bat:BAS4560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28599.1.
AE017334 Genomic DNA. Translation: AAT34033.1.
AE017225 Genomic DNA. Translation: AAT56857.1.
CP009325 Genomic DNA. Translation: AJG67000.1.
CP009331 Genomic DNA. Translation: AJG69784.1.
CP009328 Genomic DNA. Translation: AJG85081.1.
CP009341 Genomic DNA. Translation: AJG88366.1.
CP009464 Genomic DNA. Translation: AJH31437.1.
CP009476 Genomic DNA. Translation: AJH33065.1.
CP009697 Genomic DNA. Translation: AJH41767.1.
CP009544 Genomic DNA. Translation: AJH51007.1.
CP009700 Genomic DNA. Translation: AJH55049.1.
CP009981 Genomic DNA. Translation: AJH92859.1.
CP010322 Genomic DNA. Translation: AJI39945.1.
RefSeqiNP_847113.1. NC_003997.3.
WP_000862038.1. NZ_KN050651.1.
YP_021558.1. NC_007530.2.
YP_030807.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81KS5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ81KS5. 3 interactions.
STRINGi198094.BA_4915.

Protocols and materials databases

DNASUi1086714.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP28599; AAP28599; BA_4915.
AAT34033; AAT34033; GBAA_4915.
AAT56857; AAT56857; BAS4560.
GeneIDi1086714.
2848558.
KEGGiban:BA_4915.
bar:GBAA_4915.
bat:BAS4560.

Phylogenomic databases

HOGENOMiHOG000229981.
KOiK01895.
OMAiCYWQTET.
OrthoDBiEOG68WR2H.

Enzyme and pathway databases

BioCyciANTHRA:ACSA-MONOMER.
BANT260799:GJAJ-4617-MONOMER.
BANT261594:GJ7F-4774-MONOMER.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2002) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate PortonImported.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (DEC-2003) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames ancestorImported and Ames AncestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (SEP-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.
  5. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BA1015Imported, BA1035Imported, K3Imported, Ohio ACBImported, PAK-1Imported, PasteurImported, RA3Imported, SK-102Imported and Vollum 1BImported.
  6. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Ames_BA1004Imported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Canadian_bisonImported.

Entry informationi

Entry nameiQ81KS5_BACAN
AccessioniPrimary (citable) accession number: Q81KS5
Secondary accession number(s): E9QVY1
, E9QVY2, Q6HS81, Q6KLI0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: April 1, 2015
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.