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Protein
Submitted name:

AMP-binding enzyme family protein

Gene

acsA

Organism
Bacillus anthracis
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein predictedi

Functioni

GO - Molecular functioni

  1. acetate-CoA ligase activity Source: UniProtKB-EC
Complete GO annotation...

Keywords - Molecular functioni

LigaseImported

Enzyme and pathway databases

BioCyciANTHRA:ACSA-MONOMER.
BANT260799:GJAJ-4617-MONOMER.
BANT261594:GJ7F-4774-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
AMP-binding enzyme family proteinImported
Submitted name:
Acetate--CoA ligaseImported (EC:6.2.1.1Imported)
Submitted name:
Acetyl-CoA synthetaseImported (EC:6.2.1.1Imported)
Submitted name:
Acetyl-coenzyme A synthetaseImported
Gene namesi
Name:acsAImported
Ordered Locus Names:BA_4915Imported, BAS4560Imported, GBAA_4915Imported
ORF Names:BACvac02_5042Imported, DH23_4779Imported, DJ42_2450Imported, DJ43_4013Imported, DJ44_3002Imported, DJ45_1132Imported, DJ49_227Imported, HYU01_23945Imported, NX97_09590Imported, OY21_07970Imported, OY22_25445Imported, OY23_14915Imported, OY24_05635Imported, OY25_21300Imported, OY27_19915Imported, OY28_20050Imported, OY29_04380Imported, OY30_19925Imported, OY32_08830Imported, OY34_01475Imported, OY35_15925Imported, OY36_25065Imported, OY37_06070Imported, OY38_07695Imported, OY39_12385Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_4915.

Structurei

3D structure databases

ProteinModelPortaliQ81KS5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Phylogenomic databases

HOGENOMiHOG000229981.
KOiK01895.
OMAiCYWQTET.
OrthoDBiEOG68WR2H.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81KS5-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MKVETLPVIK GENNLPNYDE AYANFNWEEV NKNFTWNEAG RVNMAYEAID
60 70 80 90 100
KHAKSDRKNK VALYYQDGSR KEKYTFKEMK DFSNKAGNVL KNYGDVEKGD
110 120 130 140 150
RVFIFMPRSP ELYFALLGAV KLGAIVGPLF EAFMEGAVRD RLEDSEAKVL
160 170 180 190 200
ITTPELLERV PLNDLPALKT VFLVGDHVEE GGKTVAFNPL FEQASKELHI
210 220 230 240 250
EWLGREDGLI LHYTSGSTGK PKGVLHAQNA MVQHYQTAKW VLDLKEDDVY
260 270 280 290 300
WCTADPGWVT GTAYGIFAPW LVGASNVILG GRFSPEAWYE ALQDYGVTVW
310 320 330 340 350
YSAPTAFRML MGAGQDAIKK YDLSQVRHVL SVGEPLNPEV IRWGMNAFGL
360 370 380 390 400
RIHDTWWMTE TGGQVICNYP CMEIRPGSMG KPIPGVKAAI VDNEGNEVPP
410 420 430 440 450
YTMGNLAIGK GWPAMMRGIW NNKQKYESYF MPGDWYVSGD SAYMDEDGYF
460 470 480 490 500
WFQGRIDDVI MTSGERVGPF EVESKLIEHA AVAEAGVIGI PDPVRGEIIK
510 520 530 540 550
AFIALRAGYE PSEELKEEIR QFVKKGLAAH AAPRQIEFRD KLPKTRSGKI
560 570
MRRVLKAWEL NLPTGDLSTM ED
Length:572
Mass (Da):64,344
Last modified:June 1, 2003 - v1
Checksum:i13544565E6D06662
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28599.1.
AE017334 Genomic DNA. Translation: AAT34033.1.
AE017225 Genomic DNA. Translation: AAT56857.1.
CP008846 Genomic DNA. Translation: AIF58821.1.
CP007660 Genomic DNA. Translation: AIK10904.1.
CP008752 Genomic DNA. Translation: AIK54844.1.
CP007704 Genomic DNA. Translation: AIK57814.1.
CP008853 Genomic DNA. Translation: AIM08588.1.
JNOD01000014 Genomic DNA. Translation: KFJ80300.1.
JMPV01000008 Genomic DNA. Translation: KFL66407.1.
JMPU01000016 Genomic DNA. Translation: KFL70505.1.
JTAR01000047 Genomic DNA. Translation: KGZ45600.1.
JTAQ01000023 Genomic DNA. Translation: KGZ49251.1.
JTAS01000029 Genomic DNA. Translation: KGZ55419.1.
JSZP01000042 Genomic DNA. Translation: KGZ61173.1.
JSZR01000029 Genomic DNA. Translation: KGZ64440.1.
JSZQ01000035 Genomic DNA. Translation: KGZ69554.1.
JSZT01000044 Genomic DNA. Translation: KGZ76861.1.
JSZU01000032 Genomic DNA. Translation: KGZ80821.1.
JSZW01000041 Genomic DNA. Translation: KGZ96778.1.
JSZY01000046 Genomic DNA. Translation: KHA02160.1.
JSZV01000017 Genomic DNA. Translation: KHA04286.1.
JTAB01000055 Genomic DNA. Translation: KHA12736.1.
JTAC01000072 Genomic DNA. Translation: KHA15636.1.
JTAA01000006 Genomic DNA. Translation: KHA18450.1.
JTAD01000010 Genomic DNA. Translation: KHA32746.1.
JTAE01000013 Genomic DNA. Translation: KHA36100.1.
JTAF01000023 Genomic DNA. Translation: KHA41377.1.
RefSeqiNP_847113.1. NC_003997.3.
YP_021558.1. NC_007530.2.
YP_030807.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP28599; AAP28599; BA_4915.
AAT34033; AAT34033; GBAA_4915.
AAT56857; AAT56857; BAS4560.
GeneIDi1086714.
2816817.
2848558.
KEGGiban:BA_4915.
bar:GBAA_4915.
bat:BAS4560.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28599.1.
AE017334 Genomic DNA. Translation: AAT34033.1.
AE017225 Genomic DNA. Translation: AAT56857.1.
CP008846 Genomic DNA. Translation: AIF58821.1.
CP007660 Genomic DNA. Translation: AIK10904.1.
CP008752 Genomic DNA. Translation: AIK54844.1.
CP007704 Genomic DNA. Translation: AIK57814.1.
CP008853 Genomic DNA. Translation: AIM08588.1.
JNOD01000014 Genomic DNA. Translation: KFJ80300.1.
JMPV01000008 Genomic DNA. Translation: KFL66407.1.
JMPU01000016 Genomic DNA. Translation: KFL70505.1.
JTAR01000047 Genomic DNA. Translation: KGZ45600.1.
JTAQ01000023 Genomic DNA. Translation: KGZ49251.1.
JTAS01000029 Genomic DNA. Translation: KGZ55419.1.
JSZP01000042 Genomic DNA. Translation: KGZ61173.1.
JSZR01000029 Genomic DNA. Translation: KGZ64440.1.
JSZQ01000035 Genomic DNA. Translation: KGZ69554.1.
JSZT01000044 Genomic DNA. Translation: KGZ76861.1.
JSZU01000032 Genomic DNA. Translation: KGZ80821.1.
JSZW01000041 Genomic DNA. Translation: KGZ96778.1.
JSZY01000046 Genomic DNA. Translation: KHA02160.1.
JSZV01000017 Genomic DNA. Translation: KHA04286.1.
JTAB01000055 Genomic DNA. Translation: KHA12736.1.
JTAC01000072 Genomic DNA. Translation: KHA15636.1.
JTAA01000006 Genomic DNA. Translation: KHA18450.1.
JTAD01000010 Genomic DNA. Translation: KHA32746.1.
JTAE01000013 Genomic DNA. Translation: KHA36100.1.
JTAF01000023 Genomic DNA. Translation: KHA41377.1.
RefSeqiNP_847113.1. NC_003997.3.
YP_021558.1. NC_007530.2.
YP_030807.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81KS5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi198094.BA_4915.

Protocols and materials databases

DNASUi1086714.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP28599; AAP28599; BA_4915.
AAT34033; AAT34033; GBAA_4915.
AAT56857; AAT56857; BAS4560.
GeneIDi1086714.
2816817.
2848558.
KEGGiban:BA_4915.
bar:GBAA_4915.
bat:BAS4560.

Phylogenomic databases

HOGENOMiHOG000229981.
KOiK01895.
OMAiCYWQTET.
OrthoDBiEOG68WR2H.

Enzyme and pathway databases

BioCyciANTHRA:ACSA-MONOMER.
BANT260799:GJAJ-4617-MONOMER.
BANT261594:GJ7F-4774-MONOMER.

Family and domain databases

InterProiIPR025110. AMP-bd_C.
IPR020845. AMP-binding_CS.
IPR000873. AMP-dep_Synth/Lig.
[Graphical view]
PfamiPF00501. AMP-binding. 1 hit.
PF13193. AMP-binding_C. 1 hit.
[Graphical view]
PROSITEiPS00455. AMP_BINDING. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate PortonImported.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.
  5. Tong Y.G., Huang Y., An X.P., Li S.S., Mi Z.Q., Pei G.Q., Zhang Z.Y., Fan H.
    Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Cvac02Imported.
  6. "Complete Genome Sequence of Bacillus anthracis HYU01, Isolated from Soil Samples in the Korean Peninsula."
    Kim S.K., Chung W.H., Kim S.H., Jung K.H., Kim N., Chai Y.G.
    Genome Announc. 2:e00769-14(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HYU01Imported.
  7. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: A.Br.003Imported, Smith 1013Imported and Zimbabwe 89Imported.
  8. "Draft Genome Sequence of Bacillus anthracis STI."
    Okinaka R.T., Challacombe J.F., Drees K., Birdsell D.N., Janke N., Naumann A., Seymour M., O'Neill H.H., Schupp J., Sahl J., Foster J.T., Pearson T., Keim P.
    Submitted (MAY-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: STI-1Imported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BFVImported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Delta SterneImported.
  11. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031027Imported.
  12. "Centers for Disease Control and Prevention Bacillus anthracis whole genome sequencing."
    Hoffmaster A.R., Marston C.K., Gee J., Tiller R., Beesley C.A., Bell M., Elrod M., France M., Sammons S., Rodriguez-R L.M., Weigand M.R., Konstantinidis K.T.
    Submitted (NOV-2014) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031006Imported, 2000031023Imported, 2000031031Imported, 2000031038Imported, 2000031039Imported, 2000031075Imported, 2000031709Imported, 2000031765Imported, 2000032819Imported, 2000032879Imported, 2000032951Imported, 2000032967Imported, 2000032968Imported, 2000032975Imported, 2000032979Imported and 2000032989Imported.

Entry informationi

Entry nameiQ81KS5_BACAN
AccessioniPrimary (citable) accession number: Q81KS5
Secondary accession number(s): E9QVY1
, E9QVY2, Q6HS81, Q6KLI0
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: February 4, 2015
This is version 89 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.