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Q81KC6

- Q81KC6_BACAN

UniProt

Q81KC6 - Q81KC6_BACAN

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Protein
Submitted name:

Bis(5'-nucleosyl)-tetraphosphatase

Gene

BA_5075

Organism
Bacillus anthracis
Status
Unreviewed - Annotation score: 1 out of 5- Experimental evidence at protein leveli

Functioni

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Metal bindingi216 – 2161MagnesiumImported
Metal bindingi219 – 2191MagnesiumImported
Metal bindingi221 – 2211MagnesiumImported

GO - Molecular functioni

  1. diacylglycerol kinase activity Source: InterPro
  2. metal ion binding Source: UniProtKB-KW
  3. NAD+ kinase activity Source: InterPro

GO - Biological processi

  1. protein kinase C-activating G-protein coupled receptor signaling pathway Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

KinaseImported, Transferase

Keywords - Ligandi

MagnesiumImported, Metal-bindingImported

Enzyme and pathway databases

BioCyciBANT260799:GJAJ-4767-MONOMER.
BANT261594:GJ7F-4929-MONOMER.

Names & Taxonomyi

Protein namesi
Submitted name:
Bis(5'-nucleosyl)-tetraphosphataseImported
Submitted name:
BmrU proteinImported
Submitted name:
Diacylglycerol kinase family proteinImported
Submitted name:
Putative lipid kinase BmrUImported
Gene namesi
Ordered Locus Names:BA_5075Imported, BAS4713Imported, GBAA_5075Imported
ORF Names:BACvac02_5197Imported, BAHan_5323Imported, DJ42_2297Imported, DJ43_4167Imported, DJ44_3157Imported, DJ45_976Imported, DJ48_4902Imported, DJ49_72Imported, HYU01_24710Imported
OrganismiBacillus anthracisImported
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

Interactioni

Protein-protein interaction databases

STRINGi198094.BA_5075.

Structurei

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
EntryMethodResolution (Å)ChainPositionsPDBsum
3S40X-ray2.10A/B/C/D1-300[»]
3T5PX-ray2.50A/B/C/D/E/F/G/H/I/J/K/L1-300[»]
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains DAGKc domain.SAAS annotation

Phylogenomic databases

HOGENOMiHOG000261395.
KOiK07029.
OMAiEHIKPVD.
OrthoDBiEOG613098.

Family and domain databases

Gene3Di3.40.50.10330. 1 hit.
InterProiIPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR005218. Diacylglycerol/lipid_kinase.
IPR001206. Diacylglycerol_kinase_cat_dom.
[Graphical view]
PfamiPF00781. DAGK_cat. 1 hit.
[Graphical view]
SMARTiSM00046. DAGKc. 1 hit.
[Graphical view]
SUPFAMiSSF111331. SSF111331. 1 hit.
TIGRFAMsiTIGR00147. TIGR00147. 1 hit.
PROSITEiPS50146. DAGK. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81KC6 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTKTKFEKVL LIVNPKAGQG DLHTNLTKIV PPLAAAFPDL HILHTKEQGD
60 70 80 90 100
ATKYCQEFAS KVDLIIVFGG DGTVFECTNG LAPLEIRPTL AIIPGGTCND
110 120 130 140 150
FSRTLGVPQN IAEAAKLITK EHVKPVDVAK ANGQHFLNFW GIGLVSEVSN
160 170 180 190 200
NIDAEEKAKL GKIGYYLSTI RTVKNAETFP VKITYDGQVY EDEAVLVMVG
210 220 230 240 250
NGEYLGGIPS FIPNVKCDDG TLDIFVVKST GIQAFKDYIG KKLFEDSNEN
260 270 280 290 300
DIFHVKAKSI HIETEEEKEV DTDGESSLHT PCQIELLQGH FTMIYNPAVV
Length:300
Mass (Da):32,853
Last modified:June 1, 2003 - v1
Checksum:i63CBE1FD016F4140
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP28751.1.
AE017334 Genomic DNA. Translation: AAT34198.1.
AE017225 Genomic DNA. Translation: AAT57007.1.
CP008846 Genomic DNA. Translation: AIF58971.1.
CP007618 Genomic DNA. Translation: AIK33383.1.
CP008752 Genomic DNA. Translation: AIK54576.1.
CP007704 Genomic DNA. Translation: AIK57743.1.
CP008853 Genomic DNA. Translation: AIM08735.1.
CP008854 Genomic DNA. Translation: AIM14231.1.
JNOD01000014 Genomic DNA. Translation: KFJ80405.1.
JMPV01000008 Genomic DNA. Translation: KFL65654.1.
JMPU01000016 Genomic DNA. Translation: KFL72074.1.
RefSeqiNP_847265.1. NC_003997.3.
YP_021723.1. NC_007530.2.
YP_030957.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP28751; AAP28751; BA_5075.
AAT34198; AAT34198; GBAA_5075.
AAT57007; AAT57007; BAS4713.
GeneIDi1084361.
2815233.
2851502.
KEGGiban:BA_5075.
bar:GBAA_5075.
bat:BAS4713.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016879 Genomic DNA. Translation: AAP28751.1 .
AE017334 Genomic DNA. Translation: AAT34198.1 .
AE017225 Genomic DNA. Translation: AAT57007.1 .
CP008846 Genomic DNA. Translation: AIF58971.1 .
CP007618 Genomic DNA. Translation: AIK33383.1 .
CP008752 Genomic DNA. Translation: AIK54576.1 .
CP007704 Genomic DNA. Translation: AIK57743.1 .
CP008853 Genomic DNA. Translation: AIM08735.1 .
CP008854 Genomic DNA. Translation: AIM14231.1 .
JNOD01000014 Genomic DNA. Translation: KFJ80405.1 .
JMPV01000008 Genomic DNA. Translation: KFL65654.1 .
JMPU01000016 Genomic DNA. Translation: KFL72074.1 .
RefSeqi NP_847265.1. NC_003997.3.
YP_021723.1. NC_007530.2.
YP_030957.1. NC_005945.1.

3D structure databases

Select the link destinations:
PDBe
RCSB PDB
PDBj
Links Updated
Entry Method Resolution (Å) Chain Positions PDBsum
3S40 X-ray 2.10 A/B/C/D 1-300 [» ]
3T5P X-ray 2.50 A/B/C/D/E/F/G/H/I/J/K/L 1-300 [» ]
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 198094.BA_5075.

Protocols and materials databases

DNASUi 1084361.
Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP28751 ; AAP28751 ; BA_5075 .
AAT34198 ; AAT34198 ; GBAA_5075 .
AAT57007 ; AAT57007 ; BAS4713 .
GeneIDi 1084361.
2815233.
2851502.
KEGGi ban:BA_5075.
bar:GBAA_5075.
bat:BAS4713.

Phylogenomic databases

HOGENOMi HOG000261395.
KOi K07029.
OMAi EHIKPVD.
OrthoDBi EOG613098.

Enzyme and pathway databases

BioCyci BANT260799:GJAJ-4767-MONOMER.
BANT261594:GJ7F-4929-MONOMER.

Family and domain databases

Gene3Di 3.40.50.10330. 1 hit.
InterProi IPR017438. ATP-NAD_kinase_dom_1.
IPR016064. ATP-NAD_kinase_PpnK-typ.
IPR005218. Diacylglycerol/lipid_kinase.
IPR001206. Diacylglycerol_kinase_cat_dom.
[Graphical view ]
Pfami PF00781. DAGK_cat. 1 hit.
[Graphical view ]
SMARTi SM00046. DAGKc. 1 hit.
[Graphical view ]
SUPFAMi SSF111331. SSF111331. 1 hit.
TIGRFAMsi TIGR00147. TIGR00147. 1 hit.
PROSITEi PS50146. DAGK. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

« Hide 'large scale' publications
  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: AmesImported and Ames / isolate PortonImported.
  2. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: SterneImported.
  3. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames AncestorImported and Ames ancestorImported.
  4. Joardar V., Shrivastava S., Brinkac L.M., Harkins D.M., Durkin A.S., Sutton G.
    Submitted (OCT-2009) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: AmesImported.
  5. "The crystal structure of a diacylglycerol kinases from Bacillus anthracis str. Sterne."
    Tan K., Zhang R., Xu X., Cui H., Peterson S., Savchenko A., Anderson W.F., Joachimiak A.
    Submitted (MAY-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.10 ANGSTROMS).
  6. "Crystal structure of a putative diacylglycerol kinase from Bacillus anthracis str. Sterne."
    Center for Structural Genomics of Infectious Diseases (CSGID)
    Hou J., Zheng H., Chruszcz M., Cooper D.R., Onopriyenko O., Grimshaw S., Savchenko A., Anderson W.F., Minor W.
    Submitted (JUL-2011) to the PDB data bank
    Cited for: X-RAY CRYSTALLOGRAPHY (2.50 ANGSTROMS) IN COMPLEX WITH MAGNESIUM.
  7. Tong Y.G., Huang Y., An X.P., Li S.S., Mi Z.Q., Pei G.Q., Zhang Z.Y., Fan H.
    Submitted (JAN-2013) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Cvac02Imported and HanImported.
  8. "Complete Genome Sequence of Bacillus anthracis HYU01, Isolated from Soil Samples in the Korean Peninsula."
    Kim S.K., Chung W.H., Kim S.H., Jung K.H., Kim N., Chai Y.G.
    Genome Announc. 2:e00769-14(2014) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE.
    Strain: HYU01Imported.
  9. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: 2000031021Imported, A.Br.003Imported, Smith 1013Imported and Zimbabwe 89Imported.
  10. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: BFVImported.
  11. Cited for: NUCLEOTIDE SEQUENCE.
    Strain: Delta SterneImported.

Entry informationi

Entry nameiQ81KC6_BACAN
AccessioniPrimary (citable) accession number: Q81KC6
Secondary accession number(s): E9RA50
, E9RA51, Q6HRT1, Q6KL39
Entry historyi
Integrated into UniProtKB/TrEMBL: June 1, 2003
Last sequence update: June 1, 2003
Last modified: October 29, 2014
This is version 90 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

3D-structureImported, Complete proteome, Reference proteomeImported

External Data

Dasty 3