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Protein

Glycogen synthase

Gene

glgA

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Synthesizes alpha-1,4-glucan chains using ADP-glucose.UniRule annotation

Catalytic activityi

ADP-glucose + (1,4-alpha-D-glucosyl)(n) = ADP + (1,4-alpha-D-glucosyl)(n+1).UniRule annotation

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei15 – 151ADP-glucoseUniRule annotation

GO - Molecular functioni

  1. starch synthase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

BioCyciANTHRA:GLGA-MONOMER.
BANT260799:GJAJ-4812-MONOMER.
BANT261594:GJ7F-4972-MONOMER.
UniPathwayiUPA00164.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Names & Taxonomyi

Protein namesi
Recommended name:
Glycogen synthaseUniRule annotation (EC:2.4.1.21UniRule annotation)
Alternative name(s):
Starch [bacterial glycogen] synthaseUniRule annotation
Gene namesi
Name:glgAUniRule annotation
Ordered Locus Names:BA_5120, GBAA_5120, BAS4758
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000000427: Chromosome, UP000000594: Chromosome, UP000005639: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 476476Glycogen synthasePRO_0000188590Add
BLAST

Interactioni

Protein-protein interaction databases

IntActiQ81K85. 9 interactions.
STRINGi198094.BA_5120.

Structurei

3D structure databases

ProteinModelPortaliQ81K85.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.UniRule annotation

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.

Sequencei

Sequence statusi: Complete.

Q81K85-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MNILFAVSEC VPFVKSGGLA DVAGALPKEL KKLGVEVRII LPNYSLIPQK
60 70 80 90 100
LRDGCTLHKV INVPLGWRNQ YCGILKGEQD GITYYLIDNE YYFKRDSLYG
110 120 130 140 150
HYDDGERFSY FSKAVLECIP HLDFEVDVLH SHDWHTAMVN FLLREKYQDN
160 170 180 190 200
PLYEHIKTVY TIHNLQFQGV FPPEVMYDLL ELGDEYFHSE QLEFYGNVNF
210 220 230 240 250
MKGGIIASDQ ITAVSPTYKE EIQYEFFGEK LDGLLRKYND KLSGIVNGID
260 270 280 290 300
TSVYNPETDS YITAQYDADS LYEKNENKRA LQRYFGLPEK EDTPIISMVT
310 320 330 340 350
RLTKQKGLDL VRTVFREIME EDVQCIILGS GDSEYEQFFE WMAYEYPEKV
360 370 380 390 400
KVYIGFNEEL AHQVYAGSDL FLMPSLFEPC GLGQLIALAY GTIPIVRETG
410 420 430 440 450
GLNDTVQSYD EETGEGNGFS FTNFNAHDML HTVLRAIEFY HDKSVWEQLV
460 470
KQAMTEDYSW EKSALAYKKL YKSLME
Length:476
Mass (Da):54,945
Last modified:June 1, 2003 - v1
Checksum:i58D25B5B85F88E41
GO

Sequence cautioni

The sequence AAT57052.1 differs from that shown. Reason: Erroneous initiation. Curated

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28792.1.
AE017334 Genomic DNA. Translation: AAT34248.2.
AE017225 Genomic DNA. Translation: AAT57052.1. Different initiation.
RefSeqiNP_847306.1. NC_003997.3.
YP_021773.2. NC_007530.2.
YP_031002.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP28792; AAP28792; BA_5120.
AAT34248; AAT34248; GBAA_5120.
AAT57052; AAT57052; BAS4758.
GeneIDi1084436.
2819822.
2849958.
KEGGiban:BA_5120.
bar:GBAA_5120.
bat:BAS4758.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28792.1.
AE017334 Genomic DNA. Translation: AAT34248.2.
AE017225 Genomic DNA. Translation: AAT57052.1. Different initiation.
RefSeqiNP_847306.1. NC_003997.3.
YP_021773.2. NC_007530.2.
YP_031002.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81K85.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ81K85. 9 interactions.
STRINGi198094.BA_5120.

Protein family/group databases

CAZyiGT5. Glycosyltransferase Family 5.

Protocols and materials databases

DNASUi1084436.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP28792; AAP28792; BA_5120.
AAT34248; AAT34248; GBAA_5120.
AAT57052; AAT57052; BAS4758.
GeneIDi1084436.
2819822.
2849958.
KEGGiban:BA_5120.
bar:GBAA_5120.
bat:BAS4758.

Phylogenomic databases

eggNOGiCOG0297.
HOGENOMiHOG000294940.
KOiK00703.
OMAiPFWRPDI.
OrthoDBiEOG6JTC6Z.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciANTHRA:GLGA-MONOMER.
BANT260799:GJAJ-4812-MONOMER.
BANT261594:GJ7F-4972-MONOMER.

Family and domain databases

HAMAPiMF_00484. Glycogen_synth.
InterProiIPR001296. Glyco_trans_1.
IPR011835. Glycogen/starch_synth.
IPR013534. Starch_synth_cat_dom.
[Graphical view]
PfamiPF08323. Glyco_transf_5. 1 hit.
PF00534. Glycos_transf_1. 1 hit.
[Graphical view]
TIGRFAMsiTIGR02095. glgA. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
    Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J.
    , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
    Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames / isolate Porton.
  2. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Ames ancestor.
  3. "Complete genome sequence of Bacillus anthracis Sterne."
    Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
    Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Sterne.

Entry informationi

Entry nameiGLGA_BACAN
AccessioniPrimary (citable) accession number: Q81K85
Secondary accession number(s): Q6HRN6, Q6KL02
Entry historyi
Integrated into UniProtKB/Swiss-Prot: January 16, 2004
Last sequence update: June 1, 2003
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.