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Protein

Glucose-1-phosphate adenylyltransferase

Gene

glgC

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalyzes the synthesis of ADP-glucose, a sugar donor used in elongation reactions on alpha-glucans.UniRule annotation

Catalytic activityi

ATP + alpha-D-glucose 1-phosphate = diphosphate + ADP-glucose.UniRule annotation

Pathwayi: glycogen biosynthesis

This protein is involved in the pathway glycogen biosynthesis, which is part of Glycan biosynthesis.UniRule annotation
View all proteins of this organism that are known to be involved in the pathway glycogen biosynthesis and in Glycan biosynthesis.

GO - Molecular functioni

  • ATP binding Source: UniProtKB-KW
  • glucose-1-phosphate adenylyltransferase activity Source: TIGR

GO - Biological processi

  • glycogen biosynthetic process Source: TIGR
Complete GO annotation...

Keywords - Molecular functioni

Nucleotidyltransferase, Transferase

Keywords - Biological processi

Carbohydrate metabolism, Glycogen biosynthesis, Glycogen metabolism

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciANTHRA:GLGC-MONOMER.
UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
Glucose-1-phosphate adenylyltransferaseUniRule annotation (EC:2.7.7.27UniRule annotation)
Alternative name(s):
ADP-glucose pyrophosphorylaseUniRule annotation
Short name:
ADPGlc PPaseUniRule annotation
ADP-glucose synthaseUniRule annotation
Gene namesi
Name:glgCUniRule annotation
Ordered Locus Names:BA_5122, GBAA_5122, BAS4760
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001952751 – 376Glucose-1-phosphate adenylyltransferaseAdd BLAST376

Interactioni

Protein-protein interaction databases

IntActiQ81K83. 1 interactor.
STRINGi198094.BA_5122.

Structurei

3D structure databases

ProteinModelPortaliQ81K83.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105CNB. Bacteria.
COG0448. LUCA.
HOGENOMiHOG000278603.
KOiK00975.
OMAiFGCIDSD.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
HAMAPiMF_00624. GlgC. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR023049. GlgC_bac.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q81K83-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MAQKQKCVAM LLAGGKGSRL SALTKNLAKP AVPFGGKYRI IDFTLSNCAN
60 70 80 90 100
SGIETVGILT QYQPLELHNY IGIGNAWDLD RVSGGVTVLP PYAESSGVKW
110 120 130 140 150
YTGTASAIYQ NLNYLSQYEP EYVLILSGDH IYKMDYSKML DYHIEKEADV
160 170 180 190 200
SISVIEVPWD EASRFGIMNT NEEMEIVEFE EKPQFPRSNL ASMGIYIFNW
210 220 230 240 250
AILKEYLEMD ARNPESSNDF GKDVLPLLLD EGKKLMAYPF EGYWKDVGTV
260 270 280 290 300
KSLWEANMDL LRDETSLNLN DRDWRIYSVN PNEPPQYIAE KAKVEESLIN
310 320 330 340 350
EGCVIEGDVK HSVLFQGVTV EEGSMVIDSV VMPGAKIGKN VVIERAIVGS
360 370
EMVIEDGTII RPEKNVDDVV LIAEGK
Length:376
Mass (Da):42,034
Last modified:June 1, 2003 - v1
Checksum:iE786DB45B97B398E
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28794.1.
AE017334 Genomic DNA. Translation: AAT34250.1.
AE017225 Genomic DNA. Translation: AAT57054.1.
RefSeqiNP_847308.1. NC_003997.3.
WP_000057611.1. NZ_LHUO01000017.1.
YP_031004.1. NC_005945.1.

Genome annotation databases

EnsemblBacteriaiAAP28794; AAP28794; BA_5122.
AAT34250; AAT34250; GBAA_5122.
AAT57054; AAT57054; BAS4760.
GeneIDi1084437.
2849401.
KEGGiban:BA_5122.
bar:GBAA_5122.
bat:BAS4760.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA. Translation: AAP28794.1.
AE017334 Genomic DNA. Translation: AAT34250.1.
AE017225 Genomic DNA. Translation: AAT57054.1.
RefSeqiNP_847308.1. NC_003997.3.
WP_000057611.1. NZ_LHUO01000017.1.
YP_031004.1. NC_005945.1.

3D structure databases

ProteinModelPortaliQ81K83.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ81K83. 1 interactor.
STRINGi198094.BA_5122.

Protocols and materials databases

DNASUi1084437.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiAAP28794; AAP28794; BA_5122.
AAT34250; AAT34250; GBAA_5122.
AAT57054; AAT57054; BAS4760.
GeneIDi1084437.
2849401.
KEGGiban:BA_5122.
bar:GBAA_5122.
bat:BAS4760.

Phylogenomic databases

eggNOGiENOG4105CNB. Bacteria.
COG0448. LUCA.
HOGENOMiHOG000278603.
KOiK00975.
OMAiFGCIDSD.

Enzyme and pathway databases

UniPathwayiUPA00164.
BioCyciANTHRA:GLGC-MONOMER.

Family and domain databases

Gene3Di3.90.550.10. 2 hits.
HAMAPiMF_00624. GlgC. 1 hit.
InterProiIPR005836. ADP_Glu_pyroP_CS.
IPR011831. GlgC.
IPR023049. GlgC_bac.
IPR005835. NTP_transferase_dom.
IPR029044. Nucleotide-diphossugar_trans.
IPR011004. Trimer_LpxA-like.
[Graphical view]
PfamiPF00483. NTP_transferase. 1 hit.
[Graphical view]
SUPFAMiSSF51161. SSF51161. 1 hit.
SSF53448. SSF53448. 2 hits.
TIGRFAMsiTIGR02091. glgC. 1 hit.
PROSITEiPS00808. ADP_GLC_PYROPHOSPH_1. 1 hit.
PS00809. ADP_GLC_PYROPHOSPH_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiGLGC_BACAN
AccessioniPrimary (citable) accession number: Q81K83
Secondary accession number(s): Q6HRN4, Q6KL00
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: June 1, 2003
Last modified: November 2, 2016
This is version 91 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.