Q81JU4 (Q81JU4_BACAN) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Methionine aminopeptidase RuleBase RU003653
EC=3.4.11.18 RuleBase RU003653

Gene names

Name:	maP3 EMBL AAP29242.1
Ordered Locus Names:	BA_5601, GBAA_5601 EMBL AAT34747.2

Organism

Bacillus anthracis

Taxonomic identifier

1392 [NCBI]

Taxonomic lineage

Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group

Protein attributes

Sequence length	264 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Removes the N-terminal methionine from nascent proteins By similarity. RuleBase RU003653
Catalytic activity	Release of N-terminal amino acids, preferentially methionine, from peptides and arylamides. RuleBase RU003653
Cofactor	Binds 2 cobalt ions per subunit By similarity. RuleBase RU003653
Sequence similarities	Belongs to the peptidase M24A family. RuleBase RU003653

Ontologies

Keywords
Ligand	Cobalt RuleBase RU003653 Metal-binding RuleBase RU003653
Molecular function	Aminopeptidase RuleBase RU003653 EMBL AAP29242.1 Hydrolase Protease
Technical term	Complete proteome Reference proteome
Gene Ontology (GO)
Biological process	cellular process Inferred from electronic annotation. Source: InterPro proteolysis Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	aminopeptidase activity Inferred from electronic annotation. Source: UniProtKB-KW metal ion binding Inferred from electronic annotation. Source: UniProtKB-KW metalloexopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q81JU4 [UniParc]. Last modified June 1, 2003. Version 1. Checksum: AC21D93C604858DE	FASTA	264	28,912
	10 20 30 40 50 60 MIQSGKIYIR GRTVVFMIIR NEQDLEGLRK IGRIVALARE EMKKEAKPGM TTKELDLIGK 70 80 90 100 110 120 KVLDEHGAIS APEKEYDFPG VTCISVNEEV AHGIPGDRVL KEGDLVNVDV SAALDGYYAD 130 140 150 160 170 180 TGISFVLGED EAKEKLCQAA VDAFWAAMKK VKAGSKQNQI GRAVSNFAHK NGYNVIQNLT 190 200 210 220 230 240 GHGIGLSLHE APNHILSYFD PMDNALLKDG LVIAVEPFIS MKADHIIERG DDGWTFVTPD 250 260 KSLVAQCEHT VVVTRGEPII LTEI

References

[1]

"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M. Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton.

[2]

"Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor.

Cross-references

Sequence databases
EMBL GenBank DDBJ	AE016879 Genomic DNA. Translation: AAP29242.1. AE017334 Genomic DNA. Translation: AAT34747.2.
RefSeq	NP_847756.2. NC_003997.3. YP_022272.3. NC_007530.2.
3D structure databases
HSSP	HSSP built from PDB template 1C24 based on UniProtKB P07906.
ProteinModelPortal	Q81JU4.
ModBase	Search...
Protein-protein interaction databases
IntAct	Q81JU4. 7 interactions.
Protein family/group databases
MEROPS	M24.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
EnsemblBacteria	EBBACT00000008787; EBBACP00000008543; EBBACG00000008779. EBBACT00000015229; EBBACP00000014850; EBBACG00000015221.
GeneID	1085302. 2819259.
GenomeReviews	Gene locus BA_5601 in contig AE016879_GR. Gene locus GBAA_5601 in contig AE017334_GR.
KEGG	ban:BA_5601. bar:GBAA_5601.
PATRIC	18788826. VBIBacAnt69550_5559.
TIGR	BA_5601. GBAA5601.
Phylogenomic databases
GeneTree	EBGT00070000031874.
HOGENOM	HBG299384.
OMA	VFTVEPF.
ProtClustDB	PRK12896.
Family and domain databases
InterPro	IPR001714. Pept_M24_MAP. IPR000994. Pept_M24_structural-domain. IPR002467. Pept_M24A_MAP1. [Graphical view]
Gene3D	G3DSA:3.90.230.10. Peptidase_M24_cat_core. 1 hit.
KO	K01265.
Pfam	PF00557. Peptidase_M24. 1 hit. [Graphical view]
PRINTS	PR00599. MAPEPTIDASE.
SUPFAM	SSF55920. Peptidase_M24_cat_core. 1 hit.
TIGRFAMs	TIGR00500. Met_pdase_I. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q81JU4_BACAN

Accession

Primary (citable) accession number: Q81JU4
Secondary accession number(s): E9QTT6, Q6KJS1

Entry history

Integrated into UniProtKB/TrEMBL:	June 1, 2003
Last sequence update:	June 1, 2003
Last modified:	December 14, 2011
This is version 70 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)