Q81JT1 (SPEB_BACAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 64.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Agmatinase EC=3.5.3.11 Alternative name(s): Agmatine ureohydrolase Short name=AUH | ||||
| Gene names |
| ||||
| Organism | Bacillus anthracis | ||||
| Taxonomic identifier | 1392 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 290 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Catalyzes the formation of putrescine from agmatine By similarity. |
| Catalytic activity | Agmatine + H2O = putrescine + urea. |
| Cofactor | Manganese By similarity. |
| Pathway | |
| Sequence similarities | Belongs to the arginase family. Agmatinase subfamily. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Polyamine biosynthesis Putrescine biosynthesis Spermidine biosynthesis |
| Ligand | Manganese Metal-binding |
| Molecular function | Hydrolase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | putrescine biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW spermidine biosynthetic processInferred from electronic annotation. Source: UniProtKB-KW |
| Molecular function | agmatinase activity Inferred from electronic annotation. Source: EC metal ion bindingInferred from electronic annotation. Source: UniProtKB-KW |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||||
Molecule processing | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Chain | 1 – 290 | 290 | Agmatinase | PRO_0000173725 | |||||
Sites | |||||||||
| Metal binding | 112 | 1 | Manganese By similarity | ||||||
| Metal binding | 135 | 1 | Manganese By similarity | ||||||
| Metal binding | 137 | 1 | Manganese By similarity | ||||||
| Metal binding | 139 | 1 | Manganese By similarity | ||||||
| Metal binding | 216 | 1 | Manganese By similarity | ||||||
| Metal binding | 218 | 1 | Manganese By similarity | ||||||
Sequences
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References
| [1] | "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. Fraser C.M.Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton. |
| [2] | "Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor. |
| [3] | "Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne. |
| + | Additional computationally mapped references. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE016879 Genomic DNA. Translation: AAP29255.1. AE017334 Genomic DNA. Translation: AAT34764.1. AE017225 Genomic DNA. Translation: AAT57507.1. |
| RefSeq | NP_847769.1. NC_003997.3. YP_022289.1. NC_007530.2. YP_031457.1. NC_005945.1. |
3D structure databases | |
| ProteinModelPortal | Q81JT1. |
| ModBase | Search... |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000008654; EBBACP00000008410; EBBACG00000008646. EBBACT00000014000; EBBACP00000013621; EBBACG00000013992. EBBACT00000020632; EBBACP00000020117; EBBACG00000020623. |
| GeneID | 1085325. 2817842. 2848265. |
| GenomeReviews | Gene locus BA_5617 in contig AE016879_GR. Gene locus BAS5218 in contig AE017225_GR. Gene locus GBAA_5617 in contig AE017334_GR. |
| KEGG | ban:BA_5617. bar:GBAA_5617. bat:BAS5218. |
| TIGR | BA_5617. GBAA_5617. |
Phylogenomic databases | |
| GeneTree | EBGT00050000001627. |
| HOGENOM | HBG391953. |
| OMA | REMLLGF. |
| ProtClustDB | CLSK888062. |
Enzyme and pathway databases | |
| BioCyc | BANT260799:BAS5218-MONOMER. BANT261594:GBAA5617-MONOMER. |
Family and domain databases | |
| InterPro | IPR005925. Agmatinase-rel. IPR006035. Ureohydrolase. IPR023696. Ureohydrolase_domain. IPR020855. Ureohydrolase_Mn_BS. [Graphical view] |
| Gene3D | G3DSA:3.40.800.10. Ureohydrolase. 1 hit. |
| KO | K01480. |
| PANTHER | PTHR11358. Ureohydrolase. 1 hit. |
| Pfam | PF00491. Arginase. 1 hit. [Graphical view] |
| PIRSF | PIRSF036979. Arginase. 1 hit. |
| TIGRFAMs | TIGR01230. Agmatinase. 1 hit. |
| PROSITE | PS01053. ARGINASE_1. 1 hit. PS51409. ARGINASE_2. 1 hit. [Graphical view] |
| ProtoNet | Search... |
Entry information
| Entry name | SPEB_BACAN | ||||||||
| Accession | Primary (citable) accession number: Q81JT1 Secondary accession number(s): Q6HQD1, Q6KJQ8 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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