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Q81JK8 (SODM2_BACAN) Reviewed, UniProtKB/Swiss-Prot

Last modified July 9, 2014. Version 79. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Superoxide dismutase [Mn] 2

EC=1.15.1.1
Gene names
Name:sodA2
Synonyms:sodA-2
Ordered Locus Names:BA_5696, GBAA_5696, BAS5300
OrganismBacillus anthracis [Reference proteome] [HAMAP]
Taxonomic identifier1392 [NCBI]
Taxonomic lineageBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group

Protein attributes

Sequence length208 AA.
Sequence statusComplete.
Protein existenceEvidence at protein level

General annotation (Comments)

Function

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activity

2 superoxide + 2 H+ = O2 + H2O2.

Cofactor

Binds 1 manganese ion per subunit By similarity.

Subunit structure

Homodimer By similarity.

Sequence similarities

Belongs to the iron/manganese superoxide dismutase family.

Ontologies

Keywords
   LigandManganese
Metal-binding
   Molecular functionOxidoreductase
   Technical term3D-structure
Complete proteome
Reference proteome
Gene Ontology (GO)
   Molecular_functionmetal ion binding

Inferred from electronic annotation. Source: UniProtKB-KW

superoxide dismutase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 208208Superoxide dismutase [Mn] 2
PRO_0000160013

Sites

Metal binding281Manganese By similarity
Metal binding831Manganese By similarity
Metal binding1651Manganese By similarity
Metal binding1691Manganese By similarity

Secondary structure

..................................... 208
Helix Strand Turn

Details...

Sequences

Sequence LengthMass (Da)Tools
Q81JK8 [UniParc].

Last modified June 1, 2003. Version 1.
Checksum: 870D8FF1C721FD73

FASTA20824,023
        10         20         30         40         50         60 
MSSFQLPKLS YDYDELEPYI DSNTLSIHHG KHHATYVNNL NAALENYSEL HNKSLEELLC 

        70         80         90        100        110        120 
NLETLPKEIV TAVRNNGGGH YCHSLFWEVM SPRGGGEPNG DVAKVIDYYF NTFDNLKDQL 

       130        140        150        160        170        180 
SKAAISRFGS GYGWLVLDGE ELSVMSTPNQ DTPLQEGKIP LLVIDVWEHA YYLKYQNRRP 

       190        200 
EFVTNWWHTV NWDRVNEKYL QAIQSQKH 

« Hide

References

[1]"The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria."
Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. expand/collapse author list , Brinkac L.M., Gwinn M.L., DeBoy R.T., Madpu R., Daugherty S.C., Durkin A.S., Haft D.H., Nelson W.C., Peterson J.D., Pop M., Khouri H.M., Radune D., Benton J.L., Mahamoud Y., Jiang L., Hance I.R., Weidman J.F., Berry K.J., Plaut R.D., Wolf A.M., Watkins K.L., Nierman W.C., Hazen A., Cline R.T., Redmond C., Thwaite J.E., White O., Salzberg S.L., Thomason B., Friedlander A.M., Koehler T.M., Hanna P.C., Kolstoe A.-B., Fraser C.M.
Nature 423:81-86(2003) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames / isolate Porton.
[2]"The complete genome sequence of Bacillus anthracis Ames 'Ancestor'."
Ravel J., Jiang L., Stanley S.T., Wilson M.R., Decker R.S., Read T.D., Worsham P., Keim P.S., Salzberg S.L., Fraser-Liggett C.M., Rasko D.A.
J. Bacteriol. 191:445-446(2009) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Ames ancestor.
[3]"Complete genome sequence of Bacillus anthracis Sterne."
Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H.
Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Sterne.
+Additional computationally mapped references.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
AE016879 Genomic DNA. Translation: AAP29328.1.
AE017334 Genomic DNA. Translation: AAT34855.1.
AE017225 Genomic DNA. Translation: AAT57587.1.
RefSeqNP_847842.1. NC_003997.3.
YP_022380.1. NC_007530.2.
YP_031537.1. NC_005945.1.

3D structure databases

PDBe
RCSB-PDB
PDBj
EntryMethodResolution (Å)ChainPositionsPDBsum
1XREX-ray1.80A/B1-208[»]
ProteinModelPortalQ81JK8.
SMRQ81JK8. Positions 3-203.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING198094.BA_5696.

Protocols and materials databases

DNASU1085438.
StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaAAP29328; AAP29328; BA_5696.
AAT34855; AAT34855; GBAA_5696.
AAT57587; AAT57587; BAS5300.
GeneID1085438.
2817089.
2853067.
KEGGban:BA_5696.
bar:GBAA_5696.
bat:BAS5300.

Phylogenomic databases

eggNOGCOG0605.
HOGENOMHOG000013583.
KOK04564.
OMAKIGIFNN.
OrthoDBEOG63NMNT.

Enzyme and pathway databases

BioCycANTHRA:SODA-2-MONOMER.
BANT260799:GJAJ-5373-MONOMER.
BANT261594:GJ7F-5549-MONOMER.

Family and domain databases

InterProIPR001189. Mn/Fe_SOD.
IPR019833. Mn/Fe_SOD_BS.
IPR019832. Mn/Fe_SOD_C.
IPR019831. Mn/Fe_SOD_N.
[Graphical view]
PANTHERPTHR11404. PTHR11404. 1 hit.
PfamPF02777. Sod_Fe_C. 1 hit.
PF00081. Sod_Fe_N. 1 hit.
[Graphical view]
PIRSFPIRSF000349. SODismutase. 1 hit.
PRINTSPR01703. MNSODISMTASE.
SUPFAMSSF46609. SSF46609. 1 hit.
SSF54719. SSF54719. 1 hit.
PROSITEPS00088. SOD_MN. 1 hit.
[Graphical view]
ProtoNetSearch...

Other

EvolutionaryTraceQ81JK8.

Entry information

Entry nameSODM2_BACAN
AccessionPrimary (citable) accession number: Q81JK8
Secondary accession number(s): Q6HQ51, Q6KJJ4
Entry history
Integrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: June 1, 2003
Last modified: July 9, 2014
This is version 79 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PDB cross-references

Index of Protein Data Bank (PDB) cross-references