Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Superoxide dismutase [Mn] 2

Gene

sodA2

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

Destroys superoxide anion radicals which are normally produced within the cells and which are toxic to biological systems.

Catalytic activityi

2 superoxide + 2 H+ = O2 + H2O2.

Cofactori

Mn2+By similarityNote: Binds 1 Mn2+ ion per subunit.By similarity

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Metal bindingi28ManganeseBy similarity1
Metal bindingi83ManganeseBy similarity1
Metal bindingi165ManganeseBy similarity1
Metal bindingi169ManganeseBy similarity1

GO - Molecular functioni

GO - Biological processi

  • removal of superoxide radicals Source: TIGR

Keywordsi

Molecular functionOxidoreductase
LigandManganese, Metal-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Superoxide dismutase [Mn] 2 (EC:1.15.1.1)
Gene namesi
Name:sodA2
Synonyms:sodA-2
Ordered Locus Names:BA_5696, GBAA_5696, BAS5300
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome
  • UP000000427 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001600131 – 208Superoxide dismutase [Mn] 2Add BLAST208

Interactioni

Subunit structurei

Homodimer.By similarity

Protein-protein interaction databases

STRINGi260799.BAS5300

Structurei

Secondary structure

1208
Legend: HelixTurnBeta strandPDB Structure known for this area
Show more details
Feature keyPosition(s)DescriptionActionsGraphical viewLength
Turni13 – 19Combined sources7
Helixi22 – 30Combined sources9
Helixi32 – 44Combined sources13
Helixi48 – 50Combined sources3
Helixi55 – 60Combined sources6
Helixi62 – 64Combined sources3
Turni67 – 69Combined sources3
Helixi70 – 88Combined sources19
Helixi100 – 110Combined sources11
Helixi113 – 125Combined sources13
Beta strandi129 – 138Combined sources10
Beta strandi141 – 148Combined sources8
Helixi153 – 156Combined sources4
Beta strandi159 – 165Combined sources7
Helixi168 – 170Combined sources3
Helixi172 – 175Combined sources4
Helixi179 – 186Combined sources8
Helixi187 – 189Combined sources3
Helixi192 – 202Combined sources11

3D structure databases

Select the link destinations:
PDBei
RCSB PDBi
PDBji
Links Updated
PDB entryMethodResolution (Å)ChainPositionsPDBsum
1XREX-ray1.80A/B1-208[»]
ProteinModelPortaliQ81JK8
SMRiQ81JK8
ModBaseiSearch...
MobiDBiSearch...

Miscellaneous databases

EvolutionaryTraceiQ81JK8

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

eggNOGiENOG4105CK4 Bacteria
COG0605 LUCA
HOGENOMiHOG000013583
KOiK04564
OMAiFGTGWVW

Family and domain databases

Gene3Di1.10.287.990, 1 hit
2.40.500.20, 1 hit
InterProiView protein in InterPro
IPR001189 Mn/Fe_SOD
IPR019833 Mn/Fe_SOD_BS
IPR019832 Mn/Fe_SOD_C
IPR019831 Mn/Fe_SOD_N
IPR036324 Mn/Fe_SOD_N_sf
IPR036314 SOD_C_sf
PfamiView protein in Pfam
PF02777 Sod_Fe_C, 1 hit
PF00081 Sod_Fe_N, 1 hit
PIRSFiPIRSF000349 SODismutase, 1 hit
PRINTSiPR01703 MNSODISMTASE
SUPFAMiSSF46609 SSF46609, 1 hit
SSF54719 SSF54719, 1 hit
PROSITEiView protein in PROSITE
PS00088 SOD_MN, 1 hit

Sequencei

Sequence statusi: Complete.

Q81JK8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSSFQLPKLS YDYDELEPYI DSNTLSIHHG KHHATYVNNL NAALENYSEL
60 70 80 90 100
HNKSLEELLC NLETLPKEIV TAVRNNGGGH YCHSLFWEVM SPRGGGEPNG
110 120 130 140 150
DVAKVIDYYF NTFDNLKDQL SKAAISRFGS GYGWLVLDGE ELSVMSTPNQ
160 170 180 190 200
DTPLQEGKIP LLVIDVWEHA YYLKYQNRRP EFVTNWWHTV NWDRVNEKYL

QAIQSQKH
Length:208
Mass (Da):24,023
Last modified:June 1, 2003 - v1
Checksum:i870D8FF1C721FD73
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA Translation: AAP29328.1
AE017334 Genomic DNA Translation: AAT34855.1
AE017225 Genomic DNA Translation: AAT57587.1
RefSeqiNP_847842.1, NC_003997.3
WP_000094049.1, NZ_NRJB01000010.1
YP_031537.1, NC_005945.1

Genome annotation databases

EnsemblBacteriaiAAP29328; AAP29328; BA_5696
AAT34855; AAT34855; GBAA_5696
AAT57587; AAT57587; BAS5300
GeneIDi1085438
2853067
KEGGiban:BA_5696
bar:GBAA_5696
bat:BAS5300
PATRICifig|198094.11.peg.5658

Similar proteinsi

Entry informationi

Entry nameiSODM2_BACAN
AccessioniPrimary (citable) accession number: Q81JK8
Secondary accession number(s): Q6HQ51, Q6KJJ4
Entry historyiIntegrated into UniProtKB/Swiss-Prot: August 29, 2003
Last sequence update: June 1, 2003
Last modified: April 25, 2018
This is version 103 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

3D-structure, Complete proteome, Reference proteome
UniProt is an ELIXIR core data resource
Main funding by: National Institutes of Health