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Protein

Ribonuclease P protein component

Gene

rnpA

Organism
Bacillus anthracis
Status
Reviewed-Annotation score: -Protein inferred from homologyi

Functioni

RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.UniRule annotation

Catalytic activityi

Endonucleolytic cleavage of RNA, removing 5'-extranucleotides from tRNA precursor.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionEndonuclease, Hydrolase, Nuclease, RNA-binding
Biological processtRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
Ribonuclease P protein componentUniRule annotation (EC:3.1.26.5UniRule annotation)
Short name:
RNase P proteinUniRule annotation
Short name:
RNaseP proteinUniRule annotation
Alternative name(s):
Protein C5UniRule annotation
Gene namesi
Name:rnpAUniRule annotation
Ordered Locus Names:BA_5737, GBAA_5737, BAS5340
OrganismiBacillus anthracis
Taxonomic identifieri1392 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
Proteomesi
  • UP000000594 Componenti: Chromosome
  • UP000000427 Componenti: Chromosome

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001984171 – 119Ribonuclease P protein componentAdd BLAST119

Interactioni

Subunit structurei

Consists of a catalytic RNA component (M1 or rnpB) and a protein subunit.UniRule annotation

Protein-protein interaction databases

STRINGi260799.BAS5340

Structurei

3D structure databases

ProteinModelPortaliQ81JH0
SMRiQ81JH0
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the RnpA family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4105M7T Bacteria
COG0594 LUCA
HOGENOMiHOG000266301
KOiK03536
OMAiFEACIRR

Family and domain databases

Gene3Di3.30.230.10, 1 hit
HAMAPiMF_00227 RNase_P, 1 hit
InterProiView protein in InterPro
IPR020568 Ribosomal_S5_D2-typ_fold
IPR014721 Ribosomal_S5_D2-typ_fold_subgr
IPR000100 RNase_P
IPR020539 RNase_P_CS
PANTHERiPTHR33992 PTHR33992, 1 hit
PfamiView protein in Pfam
PF00825 Ribonuclease_P, 1 hit
ProDomiView protein in ProDom or Entries sharing at least one domain
PD003629 Ribonuclease_P, 1 hit
SUPFAMiSSF54211 SSF54211, 1 hit
TIGRFAMsiTIGR00188 rnpA, 1 hit
PROSITEiView protein in PROSITE
PS00648 RIBONUCLEASE_P, 1 hit

Sequencei

Sequence statusi: Complete.

Q81JH0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKKKHRIKKN DEFQTVFQKG KSNANRQFVV YQLDKEEQPN FRIGLSVSKK
60 70 80 90 100
IGNAVVRNRI KRMIRQSITE LKDEIDSGKD FVIIARKPCA EMTYEELKKS
110
LIHVFKRSGM KRIKSSVRK
Length:119
Mass (Da):14,027
Last modified:June 1, 2003 - v1
Checksum:i87D7F53F280111D5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AE016879 Genomic DNA Translation: AAP29368.1
AE017334 Genomic DNA Translation: AAT34898.1
AE017225 Genomic DNA Translation: AAT57627.1
RefSeqiNP_847882.1, NC_003997.3
WP_000726628.1, NZ_PPES01000006.1
YP_031577.1, NC_005945.1

Genome annotation databases

EnsemblBacteriaiAAP29368; AAP29368; BA_5737
AAT34898; AAT34898; GBAA_5737
AAT57627; AAT57627; BAS5340
GeneIDi1085509
2847955
KEGGiban:BA_5737
bar:GBAA_5737
bat:BAS5340
PATRICifig|198094.11.peg.5698

Similar proteinsi

Entry informationi

Entry nameiRNPA_BACAN
AccessioniPrimary (citable) accession number: Q81JH0
Secondary accession number(s): Q6HQ11, Q6KJF6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: March 29, 2004
Last sequence update: June 1, 2003
Last modified: May 23, 2018
This is version 99 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

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