Q81JE6 (MURG2_BACAN) Reviewed, UniProtKB/Swiss-Prot
Last modified
November 16, 2011.
Version 76.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2 EC=2.4.1.227 Alternative name(s): Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase 2 | ||||||
| Gene names |
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| Organism | Bacillus anthracis | ||||||
| Taxonomic identifier | 1392 [NCBI] | ||||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 352 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Function | Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc-(pentapeptide)GlcNAc (lipid intermediate II) By similarity. HAMAP MF_00033 |
| Catalytic activity | UDP-N-acetylglucosamine + Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol = UDP + GlcNAc-(1->4)-Mur2Ac(oyl-L-Ala-gamma-D-Glu-L-Lys-D-Ala-D-Ala)-diphosphoundecaprenol. HAMAP MF_00033 |
| Pathway | Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00033 |
| Subcellular location | Cell membrane; Peripheral membrane protein By similarity HAMAP MF_00033. |
| Sequence similarities | Belongs to the glycosyltransferase 28 family. MurG subfamily. |
Ontologies
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 352 | 352 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase 2 HAMAP MF_00033 | PRO_0000109139 | |||
Sequences
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References
| [1] | "The genome sequence of Bacillus anthracis Ames and comparison to closely related bacteria." Read T.D., Peterson S.N., Tourasse N.J., Baillie L.W., Paulsen I.T., Nelson K.E., Tettelin H., Fouts D.E., Eisen J.A., Gill S.R., Holtzapple E.K., Okstad O.A., Helgason E., Rilstone J., Wu M., Kolonay J.F., Beanan M.J., Dodson R.J. Fraser C.M.Nature 423:81-86(2003) [PubMed: 12721629] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames / isolate Porton. |
| [2] | "Bacillus anthracis comparative genomics." Ravel J., Rasko D.A., Shumway M.F., Jiang L., Cer R.Z., Federova N.B., Wilson M., Stanley S., Decker S., Read T.D., Salzberg S.L., Fraser C.M. Submitted (MAY-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Ames ancestor. |
| [3] | "Complete genome sequence of Bacillus anthracis Sterne." Brettin T.S., Bruce D., Challacombe J.F., Gilna P., Han C., Hill K., Hitchcock P., Jackson P., Keim P., Longmire J., Lucas S., Okinaka R., Richardson P., Rubin E., Tice H. Submitted (JAN-2004) to the EMBL/GenBank/DDBJ databases Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Sterne. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE016879 Genomic DNA. Translation: AAP28188.1. AE017334 Genomic DNA. Translation: AAT33595.1. AE017225 Genomic DNA. Translation: AAT56455.1. |
| RefSeq | NP_846702.1. NC_003997.3. YP_021120.1. NC_007530.2. YP_030404.1. NC_005945.1. |
3D structure databases | |
| ProteinModelPortal | Q81JE6. |
| ModBase | Search... |
Protein family/group databases | |
| CAZy | GT28. Glycosyltransferase Family 28. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000012750; EBBACP00000012506; EBBACG00000012742. EBBACT00000017253; EBBACP00000016874; EBBACG00000017244. EBBACT00000022062; EBBACP00000021547; EBBACG00000022053. |
| GeneID | 1087934. 2816755. 2853063. |
| GenomeReviews | Gene locus BA_4477 in contig AE016879_GR. Gene locus BAS4155 in contig AE017225_GR. Gene locus GBAA_4477 in contig AE017334_GR. |
| KEGG | ban:BA_4477. bar:GBAA_4477. bat:BAS4155. |
| TIGR | BA_4477. GBAA_4477. |
Phylogenomic databases | |
| GeneTree | EBGT00050000001194. |
| HOGENOM | HBG617076. |
| OMA | HICGKGN. |
| ProtClustDB | PRK12446. |
Enzyme and pathway databases | |
| BioCyc | BANT260799:BAS4155-MONOMER. BANT261594:GBAA4477-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00033. MurG. [Tree] |
| InterPro | IPR006009. GlcNAc_MurG. IPR004276. Glyco_trans_28. IPR007235. Glyco_trans_28_C. [Graphical view] |
| KO | K02563. |
| PANTHER | PTHR21015:SF22. PTHR21015:SF22. 1 hit. |
| Pfam | PF04101. Glyco_tran_28_C. 1 hit. PF03033. Glyco_transf_28. 1 hit. [Graphical view] |
| TIGRFAMs | TIGR01133. MurG. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | MURG2_BACAN | ||||||||
| Accession | Primary (citable) accession number: Q81JE6 Secondary accession number(s): Q6HTD4, Q6KMM6 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

Clusters with