SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q81J01

- GLMS_BACCR

UniProt

Q81J01 - GLMS_BACCR

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Glutamine--fructose-6-phosphate aminotransferase [isomerizing]

Gene
glmS, BC_0190
Organism
Bacillus cereus (strain ATCC 14579 / DSM 31)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source By similarity.UniRule annotation

Catalytic activityi

L-glutamine + D-fructose 6-phosphate = L-glutamate + D-glucosamine 6-phosphate.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei2 – 21Nucleophile; for GATase activity By similarity
Active sitei595 – 5951For Fru-6P isomerization activity By similarity

GO - Molecular functioni

  1. carbohydrate binding Source: InterPro
  2. glutamine-fructose-6-phosphate transaminase (isomerizing) activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. carbohydrate biosynthetic process Source: InterPro
  2. glutamine metabolic process Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminotransferase, Transferase

Enzyme and pathway databases

BioCyciBCER226900:GJEU-192-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine--fructose-6-phosphate aminotransferase [isomerizing] (EC:2.6.1.16)
Alternative name(s):
D-fructose-6-phosphate amidotransferase
GFAT
Glucosamine-6-phosphate synthase
Hexosephosphate aminotransferase
L-glutamine--D-fructose-6-phosphate amidotransferase
Gene namesi
Name:glmS
Ordered Locus Names:BC_0190
OrganismiBacillus cereus (strain ATCC 14579 / DSM 31)
Taxonomic identifieri226900 [NCBI]
Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesBacillaceaeBacillusBacillus cereus group
ProteomesiUP000001417: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Initiator methioninei1 – 11Removed By similarity
Chaini2 – 600599Glutamine--fructose-6-phosphate aminotransferase [isomerizing]UniRule annotationPRO_0000135295Add
BLAST

Proteomic databases

PRIDEiQ81J01.

Interactioni

Subunit structurei

Homodimer By similarity.UniRule annotation

Protein-protein interaction databases

STRINGi226900.BC0190.

Structurei

3D structure databases

ProteinModelPortaliQ81J01.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini2 – 217216Glutamine amidotransferase type-2Add
BLAST
Domaini283 – 422140SIS 1Add
BLAST
Domaini452 – 590139SIS 2Add
BLAST

Sequence similaritiesi

Contains 2 SIS domains.

Keywords - Domaini

Glutamine amidotransferase, Repeat

Phylogenomic databases

eggNOGiCOG0449.
KOiK00820.
OMAiSVFETQT.
OrthoDBiEOG6KT2Q1.

Family and domain databases

Gene3Di3.60.20.10. 1 hit.
HAMAPiMF_00164. GlmS.
InterProiIPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view]
PANTHERiPTHR10937:SF0. PTHR10937:SF0. 1 hit.
PfamiPF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view]
SUPFAMiSSF56235. SSF56235. 1 hit.
TIGRFAMsiTIGR01135. glmS. 1 hit.
PROSITEiPS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q81J01-1 [UniParc]FASTAAdd to Basket

« Hide

MCGIVGFIGE QDAKEILLKG LEKLEYRGYD SAGIAVQAEN GVVVYKEKGR    50
IAKLREIVDE NVAASVGIGH TRWATHGVPS KVNAHPHQST SKRFTLVHNG 100
VIENYELVKK EYLQDVTFVS ETDTEVIVQL MEQQVSTGLS VEEAFRNTLS 150
LLHGSYAIGL LDAENPNMIY VAKNKSPLLV GVGDNFNVVA SDAMAMLQVT 200
DQFIELMDKE IVIVTKESIT IKNLQGETIE RAPFTAELDA SDIEKGTYPH 250
FMLKEIDEQP LVIRNIIQKY QDENGEIELN QDIRNAILDS DRIYIIACGT 300
SYHAGLVGKQ FIEKFAKMPV EVHVASEFSY NMPLLTERPF FIYISQSGET 350
ADSRAVLVQT NEMGHKALTI TNVPGSTLSR EADYTLPLYA GPEIAVASTK 400
AYTAQLAVLS ILAADIAKAK GEVLDFDLTH ELGLVANAMI ELCDQKEEMD 450
ALAKQFLATT RNCFFIGRSV DFYVGLEGAL KLKEISYIQA EGFAGGELKH 500
GTIALIENGT PVIALATQEH VNLGIRGNVK EVVARGANPC IISMKGLEME 550
GDSFVLPTVH EALAPLVAVI PLQLISYYAA LHRECDVDKP RNLAKSVTVE 600
Length:600
Mass (Da):65,822
Last modified:January 23, 2007 - v3
Checksum:i4B09F34374ED1F88
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016877 Genomic DNA. Translation: AAP07259.1.
RefSeqiNP_830058.1. NC_004722.1.

Genome annotation databases

EnsemblBacteriaiAAP07259; AAP07259; BC_0190.
GeneIDi1202543.
KEGGibce:BC0190.
PATRICi32595994. VBIBacCer54481_0181.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
AE016877 Genomic DNA. Translation: AAP07259.1 .
RefSeqi NP_830058.1. NC_004722.1.

3D structure databases

ProteinModelPortali Q81J01.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 226900.BC0190.

Proteomic databases

PRIDEi Q81J01.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai AAP07259 ; AAP07259 ; BC_0190 .
GeneIDi 1202543.
KEGGi bce:BC0190.
PATRICi 32595994. VBIBacCer54481_0181.

Phylogenomic databases

eggNOGi COG0449.
KOi K00820.
OMAi SVFETQT.
OrthoDBi EOG6KT2Q1.

Enzyme and pathway databases

BioCyci BCER226900:GJEU-192-MONOMER.

Family and domain databases

Gene3Di 3.60.20.10. 1 hit.
HAMAPi MF_00164. GlmS.
InterProi IPR017932. GATase_2_dom.
IPR000583. GATase_dom.
IPR005855. GlmS_trans.
IPR029055. Ntn_hydrolases_N.
IPR001347. SIS.
[Graphical view ]
PANTHERi PTHR10937:SF0. PTHR10937:SF0. 1 hit.
Pfami PF00310. GATase_2. 1 hit.
PF01380. SIS. 2 hits.
[Graphical view ]
SUPFAMi SSF56235. SSF56235. 1 hit.
TIGRFAMsi TIGR01135. glmS. 1 hit.
PROSITEi PS51278. GATASE_TYPE_2. 1 hit.
PS51464. SIS. 2 hits.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 14579 / DSM 31.

Entry informationi

Entry nameiGLMS_BACCR
AccessioniPrimary (citable) accession number: Q81J01
Entry historyi
Integrated into UniProtKB/Swiss-Prot: August 30, 2005
Last sequence update: January 23, 2007
Last modified: June 11, 2014
This is version 81 of the entry and version 3 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi