Q81IQ1 (PUR5_BACCR) Reviewed, UniProtKB/Swiss-Prot
Last modified
January 25, 2012.
Version 62.
History...
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order
Names·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize orderNames and origin
| Protein names | Recommended name: Phosphoribosylformylglycinamidine cyclo-ligase EC=6.3.3.1 Alternative name(s): AIR synthase AIRS Phosphoribosyl-aminoimidazole synthetase | ||||
| Gene names |
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| Organism | Bacillus cereus (strain ATCC 14579 / DSM 31) | ||||
| Taxonomic identifier | 226900 [NCBI] | ||||
| Taxonomic lineage | Bacteria › Firmicutes › Bacillales › Bacillaceae › Bacillus › Bacillus cereus group |
Protein attributes
| Sequence length | 346 AA. |
| Sequence status | Complete. |
| Protein existence | Inferred from homology |
General annotation (Comments)
| Catalytic activity | ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole. HAMAP MF_00741_B |
| Pathway | Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole from N(2)-formyl-N(1)-(5-phospho-D-ribosyl)glycinamide: step 2/2. HAMAP MF_00741_B |
| Subcellular location | Cytoplasm By similarity HAMAP MF_00741_B. |
| Sequence similarities | Belongs to the AIR synthase family. |
Ontologies
| Keywords | |
|---|---|
| Biological process | Purine biosynthesis |
| Cellular component | Cytoplasm |
| Ligand | ATP-binding Nucleotide-binding |
| Molecular function | Ligase |
| Technical term | Complete proteome Reference proteome |
| Gene Ontology (GO) | |
| Biological process | 'de novo' IMP biosynthetic process Inferred from electronic annotation. Source: InterPro |
| Cellular component | cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell |
| Molecular function | ATP binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoribosylformylglycinamidine cyclo-ligase activityInferred from electronic annotation. Source: EC |
| Complete GO annotation... | |
Sequence annotation (Features)
| Feature key | Position(s) | Length | Description | Graphical view | Feature identifier | ||
Molecule processing | |||||||
|---|---|---|---|---|---|---|---|
| Chain | 1 – 346 | 346 | Phosphoribosylformylglycinamidine cyclo-ligase HAMAP MF_00741_B | PRO_0000148195 | |||
Sequences
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References
| [1] | "Genome sequence of Bacillus cereus and comparative analysis with Bacillus anthracis." Ivanova N., Sorokin A., Anderson I., Galleron N., Candelon B., Kapatral V., Bhattacharyya A., Reznik G., Mikhailova N., Lapidus A., Chu L., Mazur M., Goltsman E., Larsen N., D'Souza M., Walunas T., Grechkin Y., Pusch G. Kyrpides N.C.Nature 423:87-91(2003) [PubMed: 12721630] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 14579 / DSM 31. |
Cross-references
Sequence databases | |
|---|---|
| EMBL GenBank DDBJ | AE016877 Genomic DNA. Translation: AAP07371.1. |
| RefSeq | NP_830170.1. NC_004722.1. |
3D structure databases | |
| ProteinModelPortal | Q81IQ1. |
| SMR | Q81IQ1. Positions 13-341. |
| ModBase | Search... |
Protein-protein interaction databases | |
| STRING | Q81IQ1. |
Proteomic databases | |
| PRIDE | Q81IQ1. |
Protocols and materials databases | |
| StructuralBiologyKnowledgebase | Search... |
Genome annotation databases | |
| EnsemblBacteria | EBBACT00000035403; EBBACP00000034609; EBBACG00000035394. |
| GeneID | 1202684. |
| GenomeReviews | Gene locus BC_0331 in contig AE016877_GR. |
| KEGG | bce:BC0331. |
| PATRIC | 32596292. VBIBacCer54481_0303. |
Phylogenomic databases | |
| eggNOG | COG0150. |
| GeneTree | EBGT00050000002660. |
| HOGENOM | HBG531222. |
| OMA | GIDMIAM. |
| PhylomeDB | Q81IQ1. |
| ProtClustDB | PRK05385. |
Enzyme and pathway databases | |
| BioCyc | BCER226900:BC_0331-MONOMER. |
Family and domain databases | |
| HAMAP | MF_00741_B. AIRS_B. [Tree] |
| InterPro | IPR000728. AIR_synth. IPR010918. AIR_synth_C. IPR004733. PurM_cligase. IPR016188. PurM_N-like. [Graphical view] |
| KO | K01933. |
| Pfam | PF00586. AIRS. 1 hit. PF02769. AIRS_C. 1 hit. [Graphical view] |
| SUPFAM | SSF56042. AIR_synth_C. 1 hit. SSF55326. PurM_N-like. 1 hit. |
| TIGRFAMs | TIGR00878. PurM. 1 hit. |
| ProtoNet | Search... |
Entry information
| Entry name | PUR5_BACCR | ||||||||
| Accession | Primary (citable) accession number: Q81IQ1 | ||||||||
| Entry history |
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| Entry status | Reviewed (UniProtKB/Swiss-Prot) | ||||||||
| Annotation program | Prokaryotic Protein Annotation Program | ||||||||
Relevant documents
| PATHWAY comments Index of metabolic and biosynthesis pathways |
| SIMILARITY comments Index of protein domains and families |

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